内蒙古呼和浩特市大气TSP和PM_(10)中PAHs的健康风险评价

于2012—2013年6月和12月采集了内蒙古呼和浩特市大气颗粒物样品,用GC-MS分析测定其中16种PAHs的浓度,并用苯并(a)芘(Ba P)致癌、致突变等效浓度、终身致癌超额危险度和预期寿命损失3个指标评价了内蒙古呼和浩特市大气颗粒物TSP和PM_(10)中PAHs的人群健康风险。结果显示:内蒙古呼和浩特市大气颗粒物TSP和PM_(10)中PAHs对成人、儿童的日均暴露剂量范围分别为0.71×10~(-6)~2.01×10~(-6)、0.45×10~(-6)~1.28×10~(-6)和0.31×10~(-6)~2.41×10~(-6)、0.19×10~(-6)~1.15×10~(-6)mg·kg~(-1)·d~(-1);TSP和PM_(10)中PAHs对成人和儿童的终身致癌超额危险度范围分别为2.21×10~(-6)~6.24×10~(-6)、1.41×10~(-6)~3.97×10~(-6)和0.95×10~(-6)~7.47×10~(-6)、0.60×10~(-6)~4.75×10~(-6),终身致癌超额危险度均处于可接受水平范围内(10-4~10~(-6))。TSP和PM_(10)中PAHs对成人和儿童的预期寿命损失范围分别为13.74~38.78、8.752~24.70和5.88~46.39、3.74~29.54 min。     

Effects of pulse current electromagnetic fields on human peripheral lymphocytes

The effects of pulsed current electromagnetic fields (PCEMF) on human peripheral lymphocytes sister chromatid exchanges (SCE), and micronuclei (MN) frequencies were investigated. PCEMF were produced by 8/20 μs pulsed current generation with two model types, a long straight wire and a solenoid. Human peripheral lymphocyte samples were exposed to PCEMF (a pulse per min, and continuing for 1 h). SCE and MN assays were used to evaluate the genotoxic effects. The results indicated that SCE and MN incidences correlated positively with B _m and dB/dt. For the long straight wire model, as B _m reached 8.48 × 10^?2 T and dB/dt = 1.06 × 10⁴ T s^?1, the effect was significant. As B _m reached 1.70 × 10^?1 T and dB/dt = 2.13 × 10⁴ T s^?1, the effect was marked. For the solenoid model, the conditions of significant effect were B _m = 0.264 T and dB/dt = 3.30 × 10³ T s^?1 and B _m = 1.32 T and dB/dt = 1.650 × 10⁴ T s^?1. Data indicated that dB/dt was an important factor in increasing the frequencies of MN and SCE in human peripheral lymphocytes.     

The evolution of pollution profile and health risk assessment for three groups SVOCs pollutants along with Beijiang River,China

Three important groups of semi-volatile organic compounds (SVOCs), polycyclic aromatic hydrocarbons (PAHs), organic chlorinated pesticides (OCPs) and phthalate esters (PAEs), were produced by various human activities and entered the water body. In this study, the pollution profiles of three species including 16 PAHs, 20 OCPs and 15 PAEs in water along the Beijiang River, China were investigated. The concentrations of Σ₁₆PAHs in the dissolved and particulate phases were obtained as 69–1.5 × 10² ng L^?1 and 2.3 × 10³–8.6 × 10⁴ ng g^?1, respectively. The levels of Σ₂₀OCPs were 23–66 ng L^?1 (dissolved phase) and 19–1.7 × 10³ ng g^?1 (particulate phase). Nevertheless, higher levels of PAEs were found both in the dissolved and particulate phases due to abuse use of plastic products. Furthermore, non-cancer and cancer risks caused by these SVOCs through the ingestion absorption and dermal absorption were also assessed. There was no non-cancer risk existed through two kinds of exposure of them at current levels, whereas certain cancer risk existed through dermal absorption of PAHs in the particulate phase in some sampling sites. The results will show scientific insights into the evaluation of the status of combined pollution in river basins, and the determination of strategies for incident control and pollutant remediation.     

Ecological and health risks of DDTs and HCHs in surface water from the upper reaches of the Huaihe River

Based on the available toxicity data and the concentrations of DDTs and HCHs in surface water from the upper reaches of the Huaihe River, overlapping areas of probability density and margin of safety (MOS₁₀) were used to estimate the risk levels of DDTs and HCHs to aquatic organisms. The overlapping areas of α-HCH, γ-HCH, p,p′-DDE, p,p′-DDD, and p,p′-DDT were found to be 9.3 × 10^?5, 4.6 × 10^?3, 4.3 × 10^?2, 2.2 × 10^?2, and 4.2 × 10^?2, respectively. The risks from DDTs were higher than those from HCHs, the risk from α-HCH being the smallest. The MOS₁₀ values of α-HCH, γ-HCH, p,p′-DDE, p,p′-DDD, and p,p′-DDT were 2.6 × 10³, 97, 5.9, 15, and 8.6, respectively, i.e. greater than 1.0, indicating limited overlaps between the distributions of exposure concentrations and of toxicity data, and thus minimal ecological risk. Health risk calculations based on incremental lifetime risks for HCHs and DDTs were conducted to evaluate human cancer risk and non-carcinogenic hazard. The total cancer risks from organochlorine pesticides (OCPs) in the studied area were in the range of 10^?8–10^?7, lower than the baseline value of acceptable risk (10^?6). Non-carcinogenic hazard indices of OCPs ranging from 10^?6 to 10^?5 were much lower than the threshold values (1.0). These results suggest that the water from the upper reaches of the Huaihe River does not pose any health risk for local residents using river water as a source for drinking water.     

4种甲氧基丙烯酸酯类杀菌剂对拟澳洲赤眼蜂成蜂的急性毒性及安全性评价

为甲氧基丙烯酸酯类杀菌剂合理使用提供科学依据,本研究采用试管药膜法测定了啶氧菌酯、吡唑醚菌酯、嘧菌酯和醚菌酯等4种药剂的原药及其制剂对拟澳洲赤眼蜂成蜂的急性毒性,并进行了安全性评价。对比原药结果发现,啶氧菌酯原药和醚菌酯原药毒性很高,LR50依次是2.66×10-4及7.32×10-4mg a.i.·cm~(-2),均属于高风险;而吡唑醚菌酯原药及嘧菌酯原药毒性较低,LR50分别为3.01×10-3和3.47×10-3mg a.i.·cm~(-2),均为中等风险药剂。对比制剂结果发现,啶氧菌酯悬浮剂毒性最高,LR50为5.02×10-5mg a.i.·cm~(-2),为极高风险药剂;其次是吡唑醚菌酯悬浮剂及乳油,LR50分别为3.78×10-3和5.80×10-3mg a.i.·cm~(-2),均为中等风险药剂;最低的是嘧菌酯水分散粒剂、悬浮剂和醚菌酯水分散粒剂,LR50均大于4.0×10-2mg a.i.·cm~(-2),均为低风险药剂。部分甲氧基丙烯酸酯类杀菌剂对天敌赤眼蜂存在较高风险,特别是啶氧菌酯,应避免田间使用,或通过避开赤眼蜂释放期来减少对赤眼蜂的伤害。     

Polybrominated diphenyl ethers in plastic products,indoor dust,sediment and fish from informal e-waste recycling sites in Vietnam: a comprehensive assessment of contamination,accumulation pattern,emissions, and human exposure

Residue concentrations of polybrominated diphenyl ethers (PBDEs) in different kinds of samples including consumer products, indoor dust, sediment and fish collected from two e-waste recycling sites, and some industrial, urban and suburban areas in Vietnam were determined to provide a comprehensive assessment of the contamination levels, accumulation pattern, emission potential and human exposure through dust ingestion and fish consumption. There was a large variation of PBDE levels in plastic parts of obsolete electronic equipment (from 1730 to 97,300 ng/g), which is a common result observed in consumer plastic products reported elsewhere. PBDE levels in indoor dust samples collected from e-waste recycling sites ranged from 250 to 8740 ng/g, which were markedly higher than those in industrial areas and household offices. Emission rate of PBDEs from plastic parts of disposed electronic equipment to dust was estimated to be in a range from 3.4 × 10^?7 to 1.2 × 10^?5 (year^?1) for total PBDEs and from 2.9 × 10^?7 to 7.2 × 10^?6 (year^?1) for BDE-209. Some fish species collected from ponds in e-waste recycling villages contained elevated levels of PBDEs, especially BDE-209, which were markedly higher than those in fish previously reported. Overall, levels and patterns of PBDE accumulation in different kinds of samples suggest significant emission from e-waste sites and that these areas are potential sources of PBDE contamination. Intakes of PBDEs via fish consumption were generally higher than those estimated through dust ingestion. Intake of BDE-99 and BDE-209 through dust ingestion contributes a large proportion due to higher concentrations in dust and fish. Body weight normalized daily intake through dust ingestion estimated for the e-waste recycling sites (0.10–3.46 ng/day/kg body wt.) were in a high range as compared to those reported in other countries. Our results highlight the potential releases of PBDEs from informal recycling activities and the high degree of human exposure and suggest the need for continuous investigations on environmental pollution and toxic impacts of e-waste-related hazardous chemicals.     

Solar-induced generation of singlet oxygen and hydroxyl radical in sewage wastewaters

Singlet oxygen (¹O₂) and hydroxyl radical (·OH) play an important role in the degradation of pollutants in surface waters. However, the mechanism underlying the photochemical generation of ¹O₂ and ·OH in wastewaters is poorly known. Here we studied the photo-induced generation of ¹O₂ and ·OH in different sewage treatment plant units. The correlation between the generation of ¹O₂ and ·OH and the water constituents was discussed. Our results show that in sewage units the ¹O₂ formation rate ranges from 2.19 × 10^?8 to 6.74 × 10^?8 mol L^?1 s^?1, and the ·OH formation rate ranges from 1.7 × 10^?11 to 3.06 × 10^?10 mol L^?1 s^?1. The average ¹O₂ formation rates in the various sewage units are similar to those in wetland and estuarine waters containing rich dissolved organic matter and 2–4 times higher than those in lake and seawater samples. The average ·OH formation rates of the sewage units are 5–50 times higher than for other water samples reported. The ·OH generation rate increased with the iron content with a correlation coefficient of 0.85, which indicates that the photo-Fenton reaction plays a dominant role in ·OH generation in sewage wastewater.     

Study on degradation process of famotidine hydrochloride in aqueous samples

The kinetics of famotidine (FAM) transformation under the influence of various factors, important from the environmental point of view, was investigated in aqueous solutions. The degradation processes using UV, H₂O₂, UV/H₂O₂, H₂O₂/Fe²⁺, and UV/H₂O₂/Fe²⁺ were studied. Direct photolysis and H₂O₂-assisted photolysis showed a pseudo-first-order kinetics, while the Fenton and the photo-Fenton processes fit second-order kinetics. The provided experiments proved a high resistance of FAM to direct photolysis. Its stability depends highly on the pH of the reaction solutions. The rate of FAM direct photolysis in acidic solutions was almost negligible. The reaction rate of FAM photolysis at pH 8–9 was 3.7 × 10^?3 min^?1 with DT₅₀ about 3 h 7 min. It was found that the presence of H₂O₂ in the reaction environment enhances the rate of photolysis of FAM. The observed rates of reaction were 5.1 × 10^?3 min^?1 and 3.7 × 10^?3 min^?1 in acidic and basic solutions, respectively. The used Fenton systems appeared to be the most efficient in FAM removal. The rate of reaction depends on concentration of Fe²⁺ and H₂O₂. It was observed that the presence of UV-light enhances the reaction rate by two to six times in comparison to the classical Fenton system. Additionally, FAM behavior in natural water under solar irradiation was examined. The irradiation experiments were carried out in batch experiments with simulated sunlight.     

全氟辛基磺酸及其替代产品的内分泌干扰效应评价

为研究全氟辛基磺酸(PFOS)及其替代品的内分泌干扰效应,将重组人雌激素/雄激素/孕激素/甲状腺激素/维甲酸受体基因的双杂交酵母暴露于不同浓度的PFOS及替代品中,并结合体外代谢活化技术检测直接和间接的类/抗激素活性。结果表明,被替代品PFOS表现为雄激素受体、甲状腺受体和维甲酸受体拮抗剂,且在代谢活化后新增了雌激素受体拮抗效应,其半数效应浓度(EC₅₀)在3.0×10^-4～4.8×10^-3 g·L^-1之间;同时,4种替代化学品没有任何效应检出,说明不会通过与核受体结合干扰天然激素的正常功能。研究结果说明,与原化学品相比,替代产品的应用在内分泌干扰效应方面可能具有更低的环境风险。     

贵阳市西郊水厂所供管网末梢水重金属污染物季节性特征及潜在健康风险评价

以贵阳市西郊水厂2014年3月和7月所供管网末梢水中10种重金属污染物检测数据为基础,进行了季节性特征分析,并采用美国环保局(USEPA)推荐的健康风险评价模型进行了潜在健康风险评价。结果表明,贵阳市西郊水厂所供管网末梢水中10种重金属的浓度均符合国家饮用水卫生标准;重金属污染物的浓度随季节呈现出不同的特征,汞、锌、硒、钼和钡5种重金属的平均浓度呈现枯水期高于丰水期的特征,而铅、铜、锰和镍4种重金属正好相反,砷浓度的季节性特征不显著;成年人的年平均致癌风险显著大于儿童,但两者年平均非致癌风险接近;儿童和成年人2类人群经口暴露途径的健康风险值均大于皮肤暴露,其中致癌风险分别在2.49×10-6~9.16×10-6和3.26×10-8~9.59×10-8之间,非致癌风险在2.29×10-8~3.20×10-8和1.85×10-10~4.14×10-10之间,且致癌风险均大于非致癌风险。贵阳市西郊水厂所供管网末梢水中10种重金属污染物致癌风险和非致癌风险均未超过最大可接受水平,未对该供水区居民的健康造成威胁。     

Evaluation of greenhouse gas emissions from wetland and agriculture ecosystems in Sanjiang Plain

Carbon dioxide (CO₂), nitrous oxide (N₂O) and methane (CH₄) are important greenhouse gases (GHGs). The objective of this study is to quantify the aggregate GHG (CH₄, N₂O and CO₂) emissions and estimate economic losses of three ecosystems (marsh, paddy field and upland) in the Sanjiang Plain, excluding the Muling-Xiangkai Plain, south of Wanda Mountain. The results indicate the economic losses from GHG emissions of marshes were from 6.40 to 7.75?×?10⁹ CNY (Chinese Yuan), those of paddy fields were from 1.41 to 3.20?×?10⁹ CNY; and from uplands were from 0.26 to 0.49?×?10⁹ CNY. Using linear trend analysis, the economic losses through GHG emissions of marshes fell between 1982 and 2005, but those from paddy fields and uplands increased. In our study, the sequence in magnitude of the economic losses from GHG emissions was: marshes > paddy fields > uplands. In fact, the economic value of GHG emissions was negative because of these adverse impacts on the environment. This article could provide a reference for calculation of GHG exchange. The results suggest that improvement of fertiliser use efficiency for more precise agricultural management and returning straw to cropland could mitigate GHG emissions and would help to achieve sustainable development.     

敌草快对藻类和溞类的急性毒性及其水中含量测定

敌草快是一种非选择性、广谱的联吡啶类触杀性除草剂,主要通过干扰植物细胞膜、破坏光合作用而快速发挥效果。为探究敌草快对水生生物的毒性,测定了该化合物对羊角月芽藻和大型溞的急性毒性,并建立了高效液相色谱法测定水中敌草快含量的方法。结果表明:检测方法在1.00×10-2~3.00×10-2mg a.i.·L-1范围内的线性相关系数为0.99995,添加回收率在90.3%~109%之间,相对标准偏差(RSD)为1.10%~10.3%,保留时间在7.2 min左右。按实测浓度和理论浓度分别计算敌草快对羊角月芽藻的72 h的半数效应浓度EyC50(72 h-EyC50),分别为3.16×10-2mg a.i.·L-1和3.32×10-2mg a.i.·L-1,均为高毒;对大型溞48 h的半数效应浓度EC50(48 h-EC50)分别为1.18×10-2mg a.i.·L-1和1.33×10-2mg a.i.·L-1,均为剧毒。     

Are barnacle larvae able to escape from the threat of UV?

Earlier laboratory experiments suggested that environmental levels of UV-B radiation can damage the eyes of barnacle naupliar larvae and impair their phototactic behaviors. However, since barnacle larvae may avoid UV by migrating to deeper waters, it is not known whether such impairment would actually occur under field conditions. For the first time, this study provides both field and laboratory evidences to show that prevailing UV-B in the natural habitat of barnacle larvae could be an important environmental factor affecting natural barnacle populations. We here showed that although barnacle nauplii may avoid UV-B irradiation by downward migration, the amount of UV energy (9.8 × 10⁻⁶ J) received by a naupliar eye during downward migration in the natural water column is within the same order of magnitude as the total energy (7.5 × 10⁻⁶ J) sufficient to cause damages to naupliar eye and impair their phototactic responses. It is possible that solar UV-B prevailing at shallow waters would pose a similar threat to other zooplankton species over large geographic scale.     

In vitro kinetic characterization of inhibition of acetylcholinesterase by organophosphate and carbamate compounds in food animals

Organophosphate, dichlorvos (2,2-dichlorovinyldimethylphosphate, DDVP), and diazinon (DZN) as well as carbamates are currently found in contaminated water, dust, soil, agricultural waste, and elsewhere in the environment, and can be harmful after accidental or deliberate exposure. Intoxication by these compounds causes a generalized cholinergic crisis due to the inhibition of acetylcholinesterase (AChE), whose major physiological role in mammalian tissues is in nervous transmission. The half-maximal inhibitory concentration (IC₅₀) was found to be higher for carbaryl than DDVP and DZN, about 3–4 times in liver and about 4–6 times in muscles. The half time (t _1/2) of inhibition (8?µmol?L^?1 DDVP or DZN; 40?µmol?L^?1 carbaryl) ranged between 4 and 16?min and decreased as follows: pig?>?cattle?>?sheep for liver tissue, and cattle?>?sheep?>?pig for muscle. Rate constants of inhibition (k _i) ranged between 43?×?10^?3 and 168?×?10^?3?min^?1 for liver and from 46?×?10^?3 to 115?×?10^?3?min^?1 for muscles. Very little residual AChE activity (<6.1%) was seen in liver, but more was seen in muscle (<17%).     

Photolytical property of L(+)-α-phenylglycine in aqueous solution

A wide range of pharmaceutical compounds have been identified in the environment, and their existence is a topic of growing concern, both for human and ecological health. The work described here has investigated the photolytic properties of L(+)-α-phenylglycine (L-α-PG-H) in aqueous solution as it can be degraded by photo-catalysis. In 266 nm laser flash photolysis of aqueous solution of L-α-PG-H saturated with nitrogen, two transient absorption bands are observed at 280–330 nm and 450–800 nm, respectively, due to L-α-PG-H radical cation and hydrated electrons (e_aq⁻). Then e_aq⁻ reacts with L-α-PG-H to form the L-α-PG-H radical anion. Decaying rate constants of e_aq⁻ observed at 720 nm is to be 8.9 × 10⁸ dm³ mol⁻¹ s⁻¹. The rate constant for oxidation of L-α-PG-H by SO₄ ⁻ is calculated as 4.5 × 10⁸ and 4.3 × 10⁸ s⁻¹ mol⁻¹ dm³, respectively. The dissociation constants (pKa) of L-α-PG-H is 3. Excited triplet of L-α-PG-H in solution is formed by laser flash photolysis. The quench rate constant of L-α-PG-H excited triplet (k _s) is determined to be 1.3 × 10⁷ dm³ mol⁻¹ s⁻¹ and k ₀ is equal to 1.7 × 10⁵ s⁻¹.     

Radiocarbon in food: a non-problem of health effects

Recently it has come to our attention that a paper was published in this journal entitled “recycling greenhouse gas fossil fuel emissions into low radiocarbon food products to reduce human genetic damage” (Williams in Environ Chem Lett 5:197–202, 2007). In this article, it is argued that food grown in a greenhouse is healthier for people, when the greenhouse is fertilised with CO₂ prepared from fossil fuels. In this comment, however, we argue that the effect on human health is completely negligible.     

Quality of tube well water intended for irrigation and human consumption with special emphasis on arsenic contamination at the area of Punjab,Pakistan

In the present study, the tube well water quality and the associated health risks, emphasizing on arsenic contamination, were investigated in rural and urban samples from Tehsil Mailsi located in Punjab, Pakistan. Arsenic concentrations (μg/L) were ranged from 12 to 448.5 and which exceeded the WHO recommended limit (10 μg/L) in all cases. The calculated average daily dose (3.3 × 10^?0.4 to 1.2 × 10^?0.2 mg/kg day) and hazard quotient (1.1–40) reflected the potential health risk to local population due to tube well water consumption as drinking purpose. Sodium percent (Na%), sodium absorption ratio, residual sodium carbonate, Kelly’s index and magnesium absorption ratio were also determined to assess the suitability of tube well water for irrigation purpose. The resulting piper plot revealed the Na–Ca–HCO₃ type water chemistry of the area and generally alkaline environment. The spatial distribution of arsenic in the tube well waters pinpoints the significant contribution of anthropogenic activities to arsenic pollution. Nevertheless, different statistical tools, including principal component analysis, hierarchical cluster analysis and correlation matrices, revealed the contribution of both natural and anthropogenic activities and alkaline type of aquifers toward the high level of arsenic contamination.     

The Influence of Varying Algal Biomass On Contaminant Exposure in Benthic-Planktonic Mesocosms: Copper (Ii)

Abstract

A series of mesocosms was exposed to a suite of light treatments and nutrient enrichment in order to generate algal communities of varying biomass. the influence of this biomass on the speciation of copper (II) was studied. Distribution coefficients ( _Kd,Lkg?1) were relatively high (log _Kd = 5 to 7), indicative of robust trace metal sequestration, and were likely controlled by the particulate organic carbon content (foc). Differences in _Kd over time and among treatments were significant, as was the relationship between _Kd and foc. Fluorescence quenching was used to determine binding capacities ( _Lt , M) and their associated binding constants ( _Kcond ,M^?1) in order to model the solid phase copper speciation. the _Kcond ranged between 2.1 and 5.2 × 10¹²M^?1, indicating a very strong copper-ligand complex, and was higher in mesocosms that received more light. the light _Lt increased over time, dramatically after the nutrient enrichment, but did not vary systematically among light treatments. _Lt ranged from 7.2 × 10? 7 to 4.9 × 10? 5 M. the large magnitudes of _Kd , _Kcond and _Lt ensured that greater than 97% of total copper in the mesocosms was complexed by organic matter. the total copper concentration ([Cu]_T, M) needed to reach a target dissolved copper concentration of 10^?12.5 M (pCu = 12.5) was determined for each mesocosm over time. [Cu]_T was between 8.02 × 10^?5 and 3.41 × 10^?2 M, and increased over time. the [Cu]_T normalized to the target pCu (Effective Dose Ratio, EDR) increased directly with increases in algal biomass, indicating a direct link between system productivity and copper exposure. Approximately 45% of the variance in EDR was explained by variance in total biomass, while the residual variance in EDR was due likely to differences in the strengths of particle associations and magnitude of binding capacities.     

Concentrations,input prediction and probabilistic biological risk assessment of polycyclic aromatic hydrocarbons (PAHs) along Gujarat coastline

A comprehensive investigation was conducted in order to assess the levels of PAHs, their input prediction and potential risks to bacterial abundance and human health along Gujarat coastline. A total of 40 sediment samples were collected at quarterly intervals within a year from two contaminated sites—Alang-Sosiya Shipbreaking Yard (ASSBRY) and Navlakhi Port (NAV), situated at Gulf of Khambhat and Gulf of Kutch, respectively. The concentration of ΣPAHs ranged from 408.00 to 54240.45 ng g^?1 dw, indicating heavy pollution of PAHs at both the contaminated sites. Furthermore, isomeric ratios and principal component analysis have revealed that inputs of PAHs at both contaminated sites were mixed-pyrogenic and petrogenic. Pearson co-relation test and regression analysis have disclosed Nap, Acel and Phe as major predictors for bacterial abundance at both contaminated sites. Significantly, cancer risk assessment of the PAHs has been exercised based on incremental lifetime cancer risks. Overall, index of cancer risk of PAHs for ASSBRY and NAV ranged from 4.11 × 10^?6–2.11 × 10^?5 and 9.08 × 10^?6–4.50 × 10^?3 indicating higher cancer risk at NAV compared to ASSBRY. The present findings provide baseline information that may help in developing advanced bioremediation and bioleaching strategies to minimize biological risk.     

Uranium quantification in groundwater and health risk from its ingestion in Haryana,India

Uranium is a naturally occurring radioactive element which may cause toxicological or radiological hazards to the public if present in drinking water. This study reports the quantification of uranium in groundwater of major towns of the district Fatehabad, Haryana, India. Uranium concentrations ranged between 0.3 and 48 μg L^?1. In 22% of the groundwater samples, uranium concentrations were higher than the World Health Organization maximum permissible limit of 30 µg L^?1. The radiological dose for males was found to be in the range of 4.8?×?10^?4–7.1?×?10^?2 mSv y^?1 and for females 3.5?×?10^?4–5.2?×?10^?2 mSv y^?1. The results showed that due to the ingestion of groundwater in the study area, radiological cancer risk is in the range of 9.1?×?10^?7–1.3?×?10^?4, lower than the risk limit. Uranium ingestion from groundwater varied from 0.02 to 3.5 µg kg^?1 day^?1, which is within acceptable limit.