Air concentrations and urinary metabolites of polycyclic aromatic hydrocarbons among paving and remixing workers

The exposure of paving workers to polycyclic aromatic hydrocarbons (PAH) during stone mastic asphalt (SMA) paving and remixing was evaluated. The effects on the workers' PAH exposure were also evaluated during the use of an industrial by-product, coal fly ash (CFA), instead of limestone as the filler in the SMA. The PAH exposure was measured by personal air sampling and by analysing the levels of urinary naphthols, phenanthrols and 1-hydroxypyrene (1-OHP) in the workers' pre- and post-shift urine samples. The respiratory PAH exposure of the paving workers (geometric mean (GM) 5.7 microg m(-3)) was about ten-fold that of the traffic controllers (GM 0.43 microg m(-3)). The levels of PAH metabolites were significantly higher (p < 0.05) in the post-shift urine samples than in the pre-shift urine samples, and the levels of metabolites in the post-shift urine of paving workers were significantly higher than in that of the controls (p < 0.01). Urinary 1-naphthol correlated well with the airborne concentrations of the two- to three-ring PAHs (r = 0.544, p = 0.003) and naphthalene (r = 0.655, p < 0.001), when non-smoking paving workers were tested. A good correlation was observed between urinary 1-OHP and the airborne concentrations of the four- to six-ring PAHs (r = 0.524, p = 0.003) as well as total PAHs (r = 0.575, p = 0.001). The concentrations of 1-OHP and phenanthrols in the urine of the pavers were significantly higher (p < 0.01) during remixing than during SMA paving. The CFA in the asphalt had no effect on the airborne PAH exposure or on the concentrations of the PAH metabolites in the paving workers' urine.     

The impact of ozone depletion on skin cancer incidence: An assessment of the Netherlands and Australia

Evidence indicates that the concentration of stratospheric ozone has already decreased globally over the past several years and additional decreases are to be expected over the coming decades. A further depletion of the ozone layer would lead to an increase in the amount of ultraviolet (UV) radiation. One of the adverse effects of particularly UV-B radiation on human health would be an increase in the incidence of skin cancer. In this study an integrated model is presented to assist in assessing the changes in skin cancer incidences in relation to changes in the amount of stratospheric ozone, for the Netherlands and Australia. Although surrounded by large uncertainties, model results show that, in view of the several delay mechanisms and, additionally, the ageing of the population, future increases in skin cancer incidence cannot be reversed.     

Estimating residential air pollution exposure among citizens in Oslo 1974-1998 using a geographical information system

Annual concentration fields of SO2 and NOx for the period 1974-1998 are calculated for a 22 x 18 km2-grid in Oslo. In a study of lung cancer and air pollution in Oslo, 16209 men living in Oslo have been followed from 1972/73 to 1998. This paper presents a method for estimating their annual residential air pollution exposure for SO2 and NOx. In the exposure assessment the National Population Register provided information on home addresses. Each participant was given an annual average air pollutant concentration outdoors of the address he lived the largest part of that year. Persons living close to streets with high traffic were given an additional concentration, and persons who moved outside Oslo were given a region value for each year. Due to regulations of the sulfur content in fuel oil and a general change of local heating systems to electricity or distant heating, the SO2-concentrations in Central Oslo were reduced during the period from about 60 microg m(-3) in 1974-75 to about 4 microg m(-3) in 1997-98. Due to the increasing traffic the NOx-concentrations have increased slowly, from about 40 microg m(-3) in 1974-84 to about 60 microg m(-3) in 1989. After the introduction of catalyst cars the concentrations were reduced to about 45 microg m(-3) in 1997-98.