Spillover effects of trade and foreign direct investment on economic growth: an implication for sustainable development

Environment, Development and Sustainability - This paper explores the advantages of international trade and foreign direct investment (FDI), which can be the main factors of transferring technology...     

Antimony induces oxidative stress and cell death in normal hepatocytes

Antimony (Sb) accumulates in the liver which is one of the target organs for metal-mediated toxicity. Although toxicity of Sb was previously investigated, the precise mechanism of Sb-induced hepatotoxicity remains to be determined. The aim of this study was to examine the role of oxidative stress, and mitochondria in the induction of cell death by Sb. Our results showed that liver cell lysis induced by Sb is mediated by reactive oxygen species (ROS) formation, lipid peroxidation and decline of mitochondrial membrane potential (MMP). Antimony-induced ROS formation, lipid peroxidation and reduction of MMP were significantly diminished by antioxidants and ROS scavengers such as dimethyl sulfoxide and mannitol; mitochondrial permeability transition (MPT) pore sealing agents such as carnitine and trifluoperazine; and adenosine triphosphate (ATP) generator, L-glutamine. Antimony-induced ROS formation, lipid peroxidation and fall in MMP were potentiated by glutathione (GSH) depletion via n-bromoheptane. MPT pore sealing agents and ATP generator inhibited hepatotoxicity, indicating Sb-activated cell death via mitochondrial pathway. Pretreatment of hepatocytes with antioxidants and ROS scavengers also blocked cell death induced by Sb, whereas GSH depletion enhances Sb-induced cell death, suggesting that oxidative stress may be directly involved in the reduction of MMP. These findings contribute to a better understanding of the mechanisms that mediate Sb-induced cell death in isolated rat hepatocytes.     

Subsistence over symbolism: the role of transnational municipal networks on cities’ climate policy innovation and adoption

Urban areas account for the majority of global greenhouse gas emissions, and increasingly, it is city governments that are adopting and implementing climate mitigation policies. Many municipal governments have joined two different global city networks that aim to promote climate policy development at the urban scale, and there is qualitative evidence that such networks play an important role in motivating cities to adopt climate policies and helping them to implement them. Our study objective is to test this proposition quantitatively, making use of a global database on cities’ environmental policy adoption, and also taking into account a large number of other factors that could play a role in climate policy adoption. Controlling for these other factors, we find that network membership does make a significant difference in the number of different measures that city governments adopt. We also find that there are significant differences between the two different networks, suggesting that the nature of the services that such networks offer their members can play an important role. Our findings lead to the provision of a set of global mitigation strategies: First of all, joining the city networks can lead to a generation of global strategies which can result into climate mitigation benefits. However, cities are required to select the network which provides proper tailor made policies. Second, in the absence of concrete international commitments at the local level, city networks lay the ground for global governance and enable cities to adopt policies independently and proactively. Third, consideration of co-benefits of climate policies can optimize the development of global strategies.     

A Solvent-Free Approach for Production of Films from Pectin and Fungal Biomass

Self-binding ability of the pectin molecules was used to produce pectin films using the compression molding technique, as an alternative method to the high energy-demanding and solvent-using casting technique. Moreover, incorporation of fungal biomass and its effects on the properties of the films was studied. Pectin powder plasticized with 30% glycerol was subjected to heat compression molding (120 °C, 1.33 MPa, 10 min) yielding pectin films with tensile strength and elongation at break of 15.7 MPa and 5.5%, respectively. The filamentous fungus Rhizopus oryzae was cultivated using the water-soluble nutrients obtained from citrus waste and yielded a biomass containing 31% proteins and 20% lipids. Comparatively, the same strain was cultivated in a semi-synthetic medium resulting in a biomass with higher protein (60%) and lower lipid content (10%). SEM images showed addition of biomass yielded films with less debris compared to the pectin films. Incorporation of the low protein content biomass up to 15% did not significantly reduce the mechanical strength of the pectin films. In contrast, addition of protein-rich biomass (up to 20%) enhanced the tensile strength of the films (16.1–19.3 MPa). Lastly, the fungal biomass reduced the water vapor permeability of the pectin films.     

Discovering and characterizing farm households’ resilience under water scarcity

Water scarcity at an alarming rate has been a limiting factor for sustainable agriculture in arid and semi-arid environments of the world. It has resulted in a number of problems such as poverty and food insecurity among farm households. Therefore, building and improving resilience, as a way to mitigate the impacts of water scarcity, is important for farm households. But one of the significant steps for planning to improve farm households’ resilience under water scarcity is investigation of the current level of resilience of these households and understanding their variances. Therefore, this study offers a classification of farm households’ diversity based on resilience. Primary data were collected from 260 randomly selected farm households in 21 villages around Parishan wetland, Iran. Farm Household Resilience Scale was used to measure resilience. Cluster analysis suggested three groups: highly, medium-, and low-resilient farm households. The results of comparing three groups revealed that highly resilient farm households characterize with higher risk management, more agricultural water security, more positive psychological traits, and better knowledge management. Also, they had better water quality, attended more agricultural extension activities, and used modern irrigation systems. Farm households’ resilience map using GIS software illustrated that there is a relationship between resilience and farm location from the wetland. The findings of this study could be used by planner and policy-makers to improve farm households’ resilience in arid and semi-arid environments. Improvement in knowledge management system is recommended as one of the most effective policy instruments in building resilience.     

Analytical solutions of nonlinear and variable-parameter transport equations for verification of numerical solvers

All numerical codes developed to solve the advection–diffusion-reaction (ADR) equation need to be verified before they are moved to the operational phase. In this paper, we initially provide four new one-dimensional analytical solutions designed to help code verification; these solutions are able to handle the challenges of the scalar transport equation including nonlinearity and spatiotemporal variability of the velocity and dispersion coefficient, and of the source term. Then, we present a solution of Burgers’ equation in a novel setup. Proposed solutions satisfy the continuity of mass for the ambient flow, which is a crucial factor for coupled hydrodynamics-transport solvers. By the end of the paper, we solve hypothetical test problems for each of the solutions numerically, and we use the derived analytical solutions for code verification. Finally, we provide assessments of results accuracy based on well-known model skill metrics.