We characterized by microdissection and fluorescence in situ hybridization (FISH) two marker chromosomes: (1) a de novo, acrocentric marker chromosome detected in 88 per cent of the amniotic fluid cells of one of two physically and developmentally normal twins; and (2) a metacentric marker chromosome present in a phenotypically normal female. Analysis of FISH probes developed from the marker chromosomes indicated that the marker chromosomes in cases 1 and 2 were del(14)(q11) and a derivative chromosome from a Robertsonian translocation, respectively. Microdissection in combination with FISH may prove to be a valuable technique in determining the chromosomal origin of de novo marker chromosomes and unbalanced structural rearrangements detected during prenatal diagnosis. 相似文献
Environmental Chemistry Letters - The rise of bacterial resistance to common clinical antibiotics is calling for alternative techniques to synthesize antibacterial drugs with high biodegradability.... 相似文献
Objective: The objective of this study was to describe demographic and injury characteristics of hospitalized injured patients involved in e-bike and motorized scooter accidents at a national level in Israel divided by different road user groups: riders and pedestrians.
Methods: This was a retrospective study based on data from the National Trauma Registry, between January 1, 2013, and December 31, 2015. All hospitalized casualties due to the involvement of an e-bike or motorized scooter were included. The type of hospitalized road user was further categorized and described by different variables.
Results: During the study period, the Israel Trauma Registry identified 795 hospitalized patients due to an e-bike or motorized scooter accident, with a dramatic 6-fold increase from 2013 to 2015. Although the majority of the injured patients were riders, 8% were pedestrians. Among the total casualties, 33% were children aged 0–14 years and among pedestrians 42% were children and 33% were seniors (ages 60+). Five persons died in hospital, 3 riders and 2 pedestrians.
Conclusions: E-bike and motorized scooter riders represent the majority of patients hospitalized due to related traffic incident. This finding questions the social and economic advantages of electric-powered 2-wheeled vehicles. 相似文献
Daily compensation irradiation for net photosynthetic rates (ΣIcomp) of Skeletonema costatum (Greville) Cleve, Chaetoceros ceratosporum Ostenfeld, Nitzschia sp., Thalassiosira nordenskiöldii Cleve, and Chroomonas salina (Wislouch) Butcher were measured during 1979 to obtain values for use in ecological models describing compensation and critical depths of marine phytoplankton. Batch cultures of these unicellular algae were exposed to temperatures and photoperiods varying from 6° to 15°C and 8.4 to 16.0 h, conditions typical of surface water in Saanich Inlet, a fjord in Vancouver Island, British Columbia, Canada. Results obtained with S. costatum and T. nordenskiöldii provided estimates of ΣIcomp varying between 1.8 and 13 J cm-2 d-1, from which a mean value of 7.0 J cm-2 d-1 was calculated for use in ecological models with neritic phytoplankton. No seasonal variation in compensation irradiation was noted because photosynthetic efficiencies, which increased as division rates increased, were balanced by respiration rates, which increased as temperature increased. Results obtained with Chaetoceros ceratosporum, Nitzschia sp., and Chroomonas salina were difficult to interpret, because respiration rates were stimulated and depressed by light, respectively, for the first two species and the last one. This light effect was greatest when cells grew under conditions of low temperature and short photoperiod. Also, under winter and spring conditions, cells of Nitzschia sp. appeared to fix CO2 in the dark and with low irradiances by mechanisms other than photosynthesis. 相似文献