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51.
K. Savolainen L. Pylkkänen H. Norppa G. Falck H. Lindberg T. Tuomi M. Vippola H. Alenius K. Hämeri J. Koivisto D. Brouwer D. Mark D. Bard M. Berges E. Jankowska M. Posniak P. Farmer R. Singh F. Krombach P. Bihari M. Seipenbusch 《Safety Science》2010,48(8):957-963
The significance of engineered nanomaterials (ENM) and nanotechnologies grows rapidly. Nanotechnology applications may have a positive marked impact on many aspects of on human every day life, for example by providing means for the production of clean energy and pure drinking water. Hundreds of consumer nano-based products are already on the market. However, very little is known of the risks of ENM to occupational safety and health (OSH), even though workers are likely to be at extra risk, as compared with other potentially exposed groups of people, because the levels of exposure are usually higher at workplaces than in other environments. However, knowledge of the exposure to, or effects of, ENM on human health and safety in occupational environments is limited and does not allow reliable assessment of risks of ENM on workers’ health. Several issues related to ENM in the workplaces require marked attention. The most topical issues include: (1) improved understanding of ENM metrics associated with ENM toxicity; (2) development of monitoring devices for ENM exposure assessment; (3) understanding the changes of ENM structure and state of agglomeration at different concentrations in aerosols; (4) understanding translocation of ENM in the human body; (5) identifying the key health effects of ENM including pulmonary toxicity, genotoxicity, carcinogenic effects, and effects on circulation; (6) development of tiered approaches for testing of safety of ENM; and (7) utilizing these data for health risk assessment, with a special emphasis on occupational environment. Available data on several ENM – ability to enter the body and reach almost any organ, to cause pulmonary inflammation and fibrosis, and even to cause increased risk of mesotheliomas in animal models, call for immediate action. It is crucial to identify those ENM that may cause occupational health and safety risks from those ENM which are innocent, hence allowing prioritization of regulatory and preventive actions at workplaces at national, regional and global levels. 相似文献
52.
Lindberg S. E. Brooks S. Lin C-J. Scott K. Meyers T. Chambers L. Landis M. Stevens R. 《Water, Air, & Soil Pollution: Focus》2001,1(5-6):295-302
We have measured total gaseous mercury concentrations(Hg°) at Point Barrow, Alaska since September 1998 in aneffort to determine the geographic extent and reaction mechanismof the so-called mercury depletion events (MDE) previouslyreported in the high Arctic at Alert, Canada. Hg° has beensampled now for nearly 2 years at Barrow. In September, 1999, webegan making the first automated measurements of reactive gaseousmercury (RGM) attempted in the Arctic, along with measurements ofHg accumulation in snowpack to determine the fate of the depleted Hg°. During the fall and early winter, Hg°and RGM exhibit only minor variation, Hg° remaining within10% of global background, near 1.6–1.8 ng m-3. The MDEperiods are quite different, however; within days of Arcticsunrise in January, Hg° exhibits major variations from themean, rapidly dropping as low as 0.05 ng m-3 and then cyclingback to typical levels, sometimes exceeding global background. These events continue throughout Arctic spring, then end abruptlyfollowing snowmelt, in early June. Prior to Arctic sunrise, RGMremains near detection (<2 pg m-3), but after sunriseincreases dramatically (to levels as high as 900 pg/m3) insynchrony with the depletion of Hg°. Both phenomenaexhibit a strong diel cycle, in parallel with UV-B. We concludethat MDE's involve rapid in-air oxidation of Hg° to aspecies of RGM by photochemically-driven reactions, probablyinvolving the same reactive bromine and chlorine compoundsinvolved in ozone destruction. Sharp increases in Hg in thesurface snowpack after sunrise coincident with periods of peakRGM suggest surface accumulation of the RGM by dry deposition. 相似文献
53.
Choices of where to carry out everyday activities in large-scale environments were conceptualized as a process of forming ‘travel plans’, and, to test a model of how such plans are formed, three experimental simulations of a planning task were performed in the laboratory. In Experiment 1, subjects (high school students) were found to choose a shortest route to travel between a number of actual, familiar locations in a town by first choosing the order between the locations that minimized straight-line (Euclidean) distances, then choosing the shortest paths between the locations in the constrained order. The order choices were, in Experiment 2, found to be made by minimizing distance locally rather than globally, except in some cases when ‘spatial configurations’ of the locations were discovered. Both the results of this experiment and of Experiment 3 suggested that such discoveries were facilitated by a simultaneous representation of the locations which was possible when they were positions on a display, committed to short-term memory or available for perceptual inspection, but to a less extent when they were actual locations. 相似文献
54.
Franke Alastair Falk Knud Hawkshaw Kevin Ambrose Skip Anderson David L. Bente Peter J. Booms Travis Burnham Kurt K. Ekenstedt Johan Fufachev Ivan Ganusevich Sergey Johansen Kenneth Johnson Jeff A. Kharitonov Sergey Koskimies Pertti Kulikova Olga Lindberg Peter Lindström Berth-Ove Mattox William G. McIntyre Carol L. Mechnikova Svetlana Mossop Dave Møller Søren Nielsen Ólafur K. Ollila Tuomo Østlyngen Arve Pokrovsky Ivan Poole Kim Restani Marco Robinson Bryce W. Rosenfield Robert Sokolov Aleksandr Sokolov Vasiliy Swem Ted Vorkamp Katrin 《Ambio》2020,49(3):762-783
Ambio - The peregrine falcon (Falco peregrinus) and the gyrfalcon (Falco rusticolus) are top avian predators of Arctic ecosystems. Although existing monitoring efforts are well established for both... 相似文献
55.
There is an urgent need to develop sustainable solutions to convert solar energy into energy carriers used in the society. In addition to solar cells generating electricity, there are several options to generate solar fuels. This paper outlines and discusses the design and engineering of photosynthetic microbial systems for the generation of renewable solar fuels, with a focus on cyanobacteria. Cyanobacteria are prokaryotic microorganisms with the same type of photosynthesis as higher plants. Native and engineered cyanobacteria have been used by us and others as model systems to examine, demonstrate, and develop photobiological H(2) production. More recently, the production of carbon-containing solar fuels like ethanol, butanol, and isoprene have been demonstrated. We are using a synthetic biology approach to develop efficient photosynthetic microbial cell factories for direct generation of biofuels from solar energy. Present progress and advances in the design, engineering, and construction of such cyanobacterial cells for the generation of a portfolio of solar fuels, e.g., hydrogen, alcohols, and isoprene, are presented and discussed. Possibilities and challenges when introducing and using synthetic biology are highlighted. 相似文献