Biological responses of workplace particles and their association with adverse health effects on miners

Epidemiological research has demonstrated the relationship between exposure to quartz dust and an elevated risk of pneumoconiosis and possible elevated risk of cancer. The current study was designed to evaluate the biological responses of workplace particles containing crystalline silica using an in vitro cell test. Respirable particle samples were sampled from four tin mines, where the standardized mortality ratio (SMR) for pneumoconiosis was 51.6 and SMR for lung cancer was 2.2 in dust-exposed miners. Alveolar macrophages (AM) are considered as the target cells for primary dust effects. The samples were then measured at 15, 30, 60 and 120 microg particle per 10(6) AM for cytoxicity with the release of glucuronidase, lactate dehydrogenase, for reactive oxygen damage with H(2)O(2) release, and for ability to induce fibrosis using the secretion of tumor necrosis factor-alpha (TNF-alpha). Pure quartz (DQ12) and corundum were used as controls. The results showed the samples from tin mines caused a higher cytoxicity when compared to corundum, yet lower when compared to quartz. However, reactive oxygen species release (148-177 nmol/3 x 10(5) AM in high concentration of 120 microg/10(6) AM) induced by the samples were significantly higher than that induced by quartz (57 nmol/3 x 10(5) AM) and corundum (62 nmol/3 x 10(5) AM). Furthermore, particle samples induced higher TNF-alpha secretion than corundum, the samples from Limu tin mine induced much higher TNF-alpha levels than that induced by DQ12 quartz. The results from the in vitro tests help elucidate the degree of hazard of dust particles in tin mines. The in vitro reaction patterns of AM also constitute a powerful tool to monitor biological and pathogenic responses of humans following dust particle exposure.     

Does the Temporal Resolution of Precipitation Input Influence the Simulated Hydrological Components Employing the SWAT Model?

This study aimed to evaluate the influence of sub‐daily precipitation time steps on model performance and hydrological components by applying the Green and Ampt infiltration method using the Soil and Water Assessment Tool (SWAT). Precipitation was measured at a resolution of 0.1 mm and aggregated to 5‐, 15‐, 30‐, and 60‐min time steps. Daily discharge data over a 10‐year period were used to calibrate and validate the model. Following a global sensitivity analysis, relevant parameters were optimized through an automatic calibration procedure using SWAT‐CUP for each time step. Daily performance statistics were almost equal among all four time steps (NSE ≈ 0.47). Discharge mainly consisted of groundwater flow (55%) and tile flow (42%), in reasonable proportions for the investigated catchment. In conclusion, model outputs were almost identical, showing simulations responded nearly independently of the chosen precipitation time step. This held true for (1) the selection of sensitive parameters, (2) performance statistics, (3) the shape of the hydrographs, and (4) flow components. However, a scenario analysis revealed that the precipitation time step becomes important when saturated hydraulic conductivities are low and curve numbers are high. The study suggests that there is no need in using precipitation time steps <1 h for lowland catchments dominated by soils with a low surface runoff potential if daily flow values are being considered. Editor's note : This paper is part of the featured series on SWAT Applications for Emerging Hydrologic and Water Quality Challenges. See the February 2017 issue for the introduction and background to the series.     

Initial Changes in Refilled Lysimeters Built with Metal Polluted Topsoil and Acidic or Calcareous Subsoils as Indicated by Changes in Drainage Water Composition

Soil translocation for recultivation of soil removed from construction sites and for the preparation of refilled lysimeters inevitably involves disturbance of soil structure, and, if intermediate storage is included, also drying and rewetting of the soil. We report on an experiment with model forest ecosystems, where uncontaminated forest subsoils were covered with non-contaminated or freshly heavy metal (mainly Zn and Cu) contaminated topsoil in large lysimeters. Monitoring of the chemical composition of the drainage water revealed two distinct soil conditioning phases. During an initial phase of about a year strongly elevated nitrate and sulfate concentrations occurred that were attributed to a mineralisation flush caused by the increased accessability of mineralisable nitrogen and sulfur in destroyed aggregates. These effects were significantly larger in lysimeters with calcareous subsoil than in those with acidic subsoil. The second phase was characterised by a gradual decrease in dissolved organic carbon and sulfate concentrations, in particular in the acidic subsoil. This decrease may be attributed to the depletion of pools made accessible during aggregate destruction or the formation of new aggregates. These chemical changes had only little effects on the concentrations of copper and zinc in the drainage water. Based on our results, it can be concluded that large refilled lysimeters can be used for many purposes without risk of compromised results, if a conditioning phase of about 1 year with sufficiently moist soil conditions is respected. Nevertheless, gradual changes in soil chemical characteristics still occur after this initial phase. Implications for the recultivation of sites using relocated soils are discussed.     

A model for estimation of potential generation of waste electrical and electronic equipment in Brazil

Sales of electrical and electronic equipment are increasing dramatically in developing countries. Usually, there are no reliable data about quantities of the waste generated. A new law for solid waste management was enacted in Brazil in 2010, and the infrastructure to treat this waste must be planned, considering the volumes of the different types of electrical and electronic equipment generated.This paper reviews the literature regarding estimation of waste electrical and electronic equipment (WEEE), focusing on developing countries, particularly in Latin America. It briefly describes the current WEEE system in Brazil and presents an updated estimate of generation of WEEE. Considering the limited available data in Brazil, a model for WEEE generation estimation is proposed in which different methods are used for mature and non-mature market products.The results showed that the most important variable is the equipment lifetime, which requires a thorough understanding of consumer behavior to estimate. Since Brazil is a rapidly expanding market, the “boom” in waste generation is still to come. In the near future, better data will provide more reliable estimation of waste generation and a clearer interpretation of the lifetime variable throughout the years.     

Ein Moosbiomonitoring zur Ermittlung atmosph?rischer Elementeintr?ge in die Euroregion Nei?e (D, PL, CZ)

Zusammenfassung  Durch ein Moosbiomonitoring sollte die H?he und die Verteilung der atmosph?rischen Deposition von 37 Elementen in der Euroregion Nei?e (ERN) nach den politischen und wirtschaftlichen Ver?nderungen erfasst und mit anderen Regionen verglichen werden. Weiterhin sollten die Akkumulationseigenschaften vonPleurozium schreberi undPolytrichum formosum, den in dieser Studie verwendeten Moosarten, miteinander verglichen werden. Bis Anfang der 90er Jahre war diese Region Teil des “Schwarzen Dreiecks”, das sich durch eine extrem hohe atmosph?rische Staubbelastung auszeichnete. Durch die Schlie?ung zahlreicher Betriebe, der Ausrüstung der Kraftwerke mit Filteranlagen, der abnehmenden Bedeutung der Braunkohle als h?uslicher Energietr?ger ver?nderte sich die Situation drastisch. Die Elementkonzentrationen in den Moosen der ERN lassen sich heute mit denen der alten Bundesl?nder vergleichen. Lediglich für Fe und Ti konnten deutlich h?here Gehalte ermittelt werden. Dies ist auf den h?heren Anteil der Braunkohle als Energietr?ger zurückzuführen. In der Region um Katowice in Oberschlesien konnten für einige Elemente mehr als 10 fach h?here Gehalte in den Moosen als in der ERN ermittelt werden. Das Oberschlesische Industrierevier weist eine derart hobe atmosph?rische Belastungen auf, dass hier ein dringender Handlungsbedarf besteht. Online-First: 21. Juni 2000