Interaction effects of lead on bioavailability and pharmacokinetics of arsenic in the rat

Arsenic (As) and lead (Pb) are common contaminants found in mine waste materials. For an evidence-based risk assessment, it is important to better understand the potential interaction of mixed contaminants; and this interaction study was investigated in an in vivo rat model. Following co-administration of a fixed dose of As^V as in sodium arsenate and different doses of Pb as lead acetate to Sprague–Dawley rats, blood arsenic concentration and bioavailability decreased. A decrease in As blood concentration when lead was co-administered was observed with increasing lead doses. Pharmacokinetic parameters for As in the blood showed faster absorption and elimination of this metalloid in the presence of Pb. The elimination half-life of As decreased from 67 days in As solo group to 27–30 with doses of Pb. Bioavailability of As was also decreased by 30–43 % in the presence of Pb. Decreased urinary excretion of Pb and tissue accumulation were also observed. It indicates lower absorption of As when co-administered with Pb. A probable explanation for these findings is that As co-administration with Pb could have resulted in the formation of less soluble lead arsenate. However, such an interaction between As and Pb could only explain about one-third of the variation when real mine waste materials containing both of these elements were administered to rats. This suggests that other effects from physical and chemical parameters could contribute to the bioavailability of arsenic in complex real environmental samples.     

The flight of<Emphasis Type="Italic"> Archaeopteryx</Emphasis>

The origin of avian flight is often equated with the phylogeny, ecology, and flying ability of the primitive Jurassic bird, Archaeopteryx. Debate persists about whether it was a terrestrial cursor or a tree dweller. Despite broad acceptance of its arboreal life style from anatomical, phylogenetic, and ecological evidence, a new version of the cursorial model was proposed recently asserting that a running Archaeopteryx could take off from the ground using thrust and sustain flight in the air. However, Archaeopteryx lacked both the powerful flight muscles and complex wing movements necessary for ground takeoff. Here we describe a flight simulation model, which suggests that for Archaeopteryx, takeoff from a perch would have been more efficient and cost-effective than from the ground. Archaeopteryx may have made short flights between trees, utilizing a novel method of phugoid gliding.     

An assessment of attraction toward affirmative action organizations: investigating the role of individual differences

Our study investigated applicant characteristics in response to organizations incorporating an affirmative action policy (AAP) statement in recruitment material. Study participants (N = 217; White upper‐level management students) randomly received recruitment material containing one of three statements (e.g., affirmative action, equal employment opportunity (EEO), or no statement regarding affirmative action or EEO) and were asked to evaluate the attractiveness of the organization publicizing the designated policy. Results indicated that individuals responded negatively to AAPs in recruitment material because of prejudice attitudes, the perceived unfairness of such programs (which we relate to equity sensitivity), or in an attempt to protect their own self‐interest (which we relate to general self‐efficacy). Additionally, individuals' equity sensitivity and general self‐efficacy both moderated the relationship between racial prejudice and organizational attractiveness. Specifically, the negative relationships between participants' prejudice attitudes and the attractiveness of organizations publicizing an affirmative action policy were stronger for benevolents (persons tolerant of situations where they are under‐rewarded) and for persons low in self‐efficacy. Implications of our findings for organizational recruitment practices are discussed. Copyright © 2006 John Wiley & Sons, Ltd.     

Leader–member social exchange (LMSX): development and validation of a scale

In the last 10 years, research devoted to the construct of leader–member exchange (LMX) has increasingly relied on the tenets of social exchange as a theoretical foundation to propose and test relationships between supervisor‐subordinate dyads and variables of significant consequence. Despite the theory underpinning such relationships, researchers continue to measure LMX with scales developed to assess vertical dyad linkage (VDL), not social exchange. To address this concern, we investigated the content validity of LMX7 (the most widely cited measure of LMX) and LMX‐MDM (a popular multidimensional measure of LMX). Findings from content validity assessments by 25 LMX experts revealed LMX7 and LMX‐MDM items are not representative of the construct of social exchange. As such, we undertook a series of studies to develop a new scale we label, leader–member social exchange (LMSX). Results indicate LMSX is able to assess different, as well as the same, components of the supervisor–subordinate relationship as previous scales while being more theoretically consistent with the notion of social exchange. Copyright © 2007 John Wiley & Sons, Ltd.     

Evaluation of Land Condition Trend Analysis for Birds on a Kansas Military Training Site

/ Land condition trend analysis (LCTA) is a long-term monitoring program used on military training lands to identify ecological changes that result from training and management activities. We initiated LCTA at the Kansas Army National Guard Training Facility (KANGTF) in Saline County, Kansas, in March 1998. This paper evaluates the LCTA methodology for birds by comparing LCTA results with a modified methodology designed to place sampling transects in field-identified rather than satellite-identified land-cover types. In the satellite-identified land-cover types developed at the site, grassland habitats included a large component of woody vegetation, which resulted in poor resolution of bird assemblages associated with the different land-cover types. Using these cover classes, mixed grass prairie included five grass/forb (g/f) and 10 woody-dependent species; old-field included four g/f and four woody-dependent species; and riparian included one g/f and six woody-dependent species. LCTA sampling was too limited in the ecologically important riparian woodland habitat with the result that bird species were not adequately sampled there. In the alternate sampling strategy, we identified three land-cover classes (grassland, hedgerow, and riparian woodland) by field reconnaissance and increased sampling in the riparian woodland. Grassland included six g/f and three woody-dependent species; hedgerow included six g/f and 20 woody-dependent species, and riparian included two g/f and 19 woody-dependent species. The modifications greatly improved the resolution of bird assemblages associated with land-cover classes at the KANGTF. Use of the alternative sampling method should improve the ability to detect long-term trends in the bird communities.     

Snowblower injuries in Vermont, 1981–1984

The Vermont Department of Health carried out two studies of snowblower injuries in Vermont during the winters of 1982–1983 and 1983–1984. The first was a case-control study in which we assessed risk factors that predisposed operators to injury during snowblower use. We found 20 persons who had been injured by snowblowers and matched 28 controls to these by neighborhood. In this study, owning a snowblower for 1 year or less and having operated a snowblower for 10 days or less in one's lifetime were significantly associated with injury. The second study was population-based. We estimated that approximately 1.5% of Vermont residents owned snowblowers during the winter of 1982–1983 and that, among snowblower owners, injuries occurred at a rate of 1.3/1,000 person-years of ownership (0.1% chance of injury).     

可持续性与消费

<正>当大自然被逾越某种极限并且发生不良变化时,环境条件即转变为环境问题;如果是由于人类的活动导致这些环境变化,并且应对这些问题需要调整社会、经济或者个人的行为,那么这些环境问题则转变为环境     

Empirical Estimation of Stream Discharge Using Channel Geometry in Low‐Gradient,Sand‐Bed Streams of the Southeastern Plains

Manning's equation is used widely to predict stream discharge (Q) from hydraulic variables when logistics constrain empirical measurements of in‐bank flow events. Uncertainty in Manning's roughness (n_M) is the major source of error in natural channels, and sand‐bed streams pose difficulties because flow resistance is affected by flow‐dependent bed configuration. Our study was designed to develop and validate models for estimating Q from channel geometry easily derived from cross‐sectional surveys and available GIS data. A database was compiled consisting of 484 Q measurements from 75 sand‐bed streams in Alabama, Georgia, South Carolina, North Carolina (Southeastern Plains), and Florida (Southern Coastal Plain), with six New Zealand streams included to develop statistical models to predict Q from hydraulic variables. Model error characteristics were estimated with leave‐one‐site‐out jackknifing. Independent data of 317 Q measurements from 55 Southeastern Plains streams indicated the model (Q = A_cR_H^0.6906S^0.1216; where A_c is the channel area, R_H is the hydraulic radius, and S is the bed slope) best predicted Q, based on Akaike's information criterion and root mean square error. Models also were developed from smaller Q range subsets to explore if subsets increased predictive ability, but error fit statistics suggested that these were not reasonable alternatives to the above equation. Thus, we recommend the above equation for predicting in‐bank Q of unbraided, sandy streams of the Southeastern Plains.     

Removal of PFOS, PFOA and other perfluoroalkyl acids at water reclamation plants in South East Queensland Australia

This paper examines the fate of perfluorinated sulfonates (PFSAs) and carboxylic acids (PFCAs) in two water reclamation plants in Australia. Both facilities take treated water directly from WWTPs and treat it further to produce high quality recycled water. The first plant utilizes adsorption and filtration methods alongside ozonation, whilst the second uses membrane processes and advanced oxidation to produce purified recycled water. At both facilities perfluorooctane sulfonate (PFOS), perfluorohexane sulfonate (PFHxS), perfluorohexanoic acid (PFHxA) and perfluorooctanoic acid (PFOA) were the most frequently detected PFCs. Concentrations of PFOS and PFOA in influent (WWTP effluent) ranged up to 3.7 and 16 ng L⁻¹ respectively, and were reduced to 0.7 and 12 ng L⁻¹ in the finished water of the ozonation plant. Throughout this facility, concentrations of most of the detected perfluoroalkyl compounds (PFCs) remained relatively unchanged with each successive treatment step. PFOS was an exception to this, with some removal following coagulation and dissolved air flotation/sand filtration (DAFF). At the second plant, influent concentrations of PFOS and PFOA ranged up to 39 and 29 ng L⁻¹. All PFCs present were removed from the finished water by reverse osmosis (RO) to concentrations below detection and reporting limits (0.4-1.5 ng L⁻¹). At both plants the observed concentrations were in the low parts per trillion range, well below provisional health based drinking water guidelines suggested for PFOS and PFOA.