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81.
The presence of fetal cells in the maternal circulation during pregnancy has been suggested by repeated observations of small numbers of cells containing Y chromatin or a Y chromosome in the blood of pregnant women. With the fluorescence-activitated cell sorter (FACS), we have used antibodies to a paternal cell surface (HLA) antigen, not present in the mother, to select fetal cells from the lymphocyte fractions of a series of maternal blood samples, collected as early as 15 weeks of gestation. These sorted cells have been examined for a second paternal genetic marker, Y chromatin. Y chromatin-containing cells were found among the sorted cells from prenatal maternal blood specimens in 8 pregnancies subsequently producing male infants whose lymphocytes reacted with the same antibodies to paternal antigen used for sorting with the FACS. In each of 17 pregnancies resulting in male infants who failed to inherit the antigen detected by the antibodies used for cell sorting, Y chromatin-containing cells were not found prenatally. The use of two paternal genetic markers, a cell surface antigen and nuclear Y chromatin, to identify fetal cells in maternal blood permits us to conclude that these cells are present in the mother's circulation, as early as 15 weeks gestation. Further development of the techniques reported here could lead to widespread screening of maternal blood samples during pregnancy for detection of fetal genetic abnormalities. 相似文献
82.
83.
Douglas W. Kuehl Edward N. Leonard Brian C. Butterworth Kenneth L. Johnson 《Environment international》1983,9(4):293-299
Over 50 non-PCB polyhalogenated organic chemicals have been identified by GC/MS in fish from the Great Lakes and other major watersheds near the Great Lakes. p,p′-DDE, hexachlorobenzene, and components of tech-chlordane were the most frequently found chemicals. Also described are advances in sample preparation methodology which allow the identification of many frequently occuring unusual chemicals. Several chemicals not previously reported in environmental samples are identified. 相似文献
84.
Leonard Champney 《Journal of the American Water Resources Association》1979,15(6):1602-1607
ABSTRACT: A general model of the policy implementation process is utilized to facilitate a discussion of the way Section 208 of PL 92-500 is being carried out on an areawide basis. A study of four “208 areas” in the “New York-Philadelphia corridor” highlights the operation of several variables used in the model. The varying political and socioeconomic conditions in geographic areas which have similar water quality problems are leading to the evolution of vastly different implementing structures, or institutional arrangements. The analysis suggests that these differences may have important implications for the success of the program in each of these areas. A major underlying theme is that such problems are characteristic of the 208 process nationwide and reflect general difficulties associated with managing water quality in a federal system. 相似文献
85.
86.
Ming Yang Faisal I. Khan Leonard Lye 《Process Safety and Environmental Protection》2013,91(5):333-342
Due to a scarcity of data, the estimate of the frequency of a rare event is a consistently challenging problem in probabilistic risk assessment (PRA). However, the use of precursor data has been shown to help in obtaining more accurate estimates. Moreover, the use of hyper-priors to represent prior parameters in the hierarchical Bayesian approach (HBA) generates more consistent results in comparison to the conventional Bayesian method. This study proposes a framework that uses a precursor-based HBA for rare event frequency estimation. The proposed method is demonstrated using the recent BP Deepwater Horizon accident in the Gulf of Mexico. The conventional Bayesian method is also applied to the same case study. The results show that the proposed approach is more effective with regards to the following perspectives: (a) using the HBA in the proposed framework provides an opportunity to take full advantage of the sparse data available and add information from indirect but relevant data; (b) the HBA is more sensitive to changes in precursor data than the conventional Bayesian method; and (c) using hyper-priors to represent prior parameters, the HBA is able to model the variability that can exist among different sources of data. 相似文献
87.
This paper examines the ability of civil society actors to champion environmental justice in an industrial risk society in South Africa by way of mobilisation and protest action. This paper presents viewpoints from key stakeholders at the Durban city level and three local case study sites to examine social capital relations to achieve environmental justice. It explores how civil society engages in social capital for mobilisation with itself and subsequent protest actions to engage with government and industry. The paper highlights that social actor response to engage in social capital for mobilisation and protests is best understood in relation to the socio-economic and political positioning of individuals or organisations. 相似文献
88.
Summary Helping-at-the-nest has been studied in a number of avian species. In many cases helping appears to enhance the reproductive success of the breeders. Because assistance is often provided to kin, this help also indirectly affects the success of the helper. In our study we examined the ways in which juvenile moorhens (Gallinula chloropus) assist their parents. We also conducted a removal experiment to determine whether the help provided increases reproductive success independently of parental and territory quality. Juvenile moorhens assist their parents by feeding younger sibs and by territory and predator defense. However, the results of our removal experiment suggest that this help has little effect on reproductive success (Table 2). Thus the helping effect originally reported in this population may be confounded by parental and territory quality. 相似文献
89.
Steven Leonard 《Environmental management》2009,44(3):430-440
Fire is widely used in conservation management of native grasslands. Burning is often carried out under conditions that are
marginal for sustained fire spread, and therefore it would be useful to be able to predict fire sustainability. There is currently
no model allowing such prediction in temperate grasslands. This study aims to identify the environmental variables that determine
whether fires will sustain in native grasslands in Tasmania, Australia, and develop a model for predicting fire sustainability
in this vegetation. Fuel characteristics and weather conditions were recorded for 111 test fires. Logistic regression modeling
identified dead fuel moisture content, fuel load, and percentage dead fuel as predictors of fire sustainability. Classification
tree modeling identified dead fuel moisture and fuel load threshold values for sustaining fires. There was also evidence indicating
a percentage dead fuel threshold. The logistic regression model and a model combining the results of the classification tree
and the percentage dead fuel threshold accurately predicted the outcomes of a small set of experimental fires. These models
are likely to have utility in predicting fire sustainability in Tasmanian grasslands and are also likely to be applicable
to similar grasslands elsewhere. 相似文献
90.
Safety belt effectiveness in preventing fatalities to drivers is examined versus a number factors (vehicle, accident, and environmental) by applying the double-pair comparison method to appropriate subsets of the Fatal Accident Reporting System (FARS) data. For each of 13 factors studied, safety belt effectiveness (the percent of fatally injured unbelted drivers who would not have been killed if they had been wearing safety belts) is estimated, as is an associated standard error of the estimate. The results, which are presented graphically, provide no evidence that safety belt effectiveness is systematically influenced by most of the factors investigated, including car mass and model year. The absence of any systematic relationship with car mass is in agreement with an earlier finding based on the pedestrian fatality exposure method; this agreement adds plausibility to the assumptions used for both the earlier and the present methods. Safety belt effectiveness is greater for single-car crashes (62 ± 5) % than for crashes involving two cars (30 ± 8) % , this difference being statistically significant at p<.02. The results suggest weakly that safety belt effectiveness is greater for two-door (48 ± 6) % than for four-door (38 ± 10) % cars, and is greater for striking (44 ± 6) % cars than for struck (27 ± 12)% cars. The above differences probably reflect higher effectiveness in frontal (or rollover) crashes than in side impacts. 相似文献