Assessment of reverse-phase chromatographic methods for determining partition coefficients

The possibility of using reverse-phase High Performance Liquid Chromatography (HPLC) and Thin Layer Chromatography (TLC) for determining partition coefficients is assessed. Whereas HPLC has been adequately validated and is recommended, TLC requires further validation. A method of calculating partition coefficients from molecular fragmental constants is also noted as being useful in certain cases.     

Groundwater Exploitation Management Under Land Subsidence Constraint: Empirical Evidence from the Hangzhou–Jiaxing–Huzhou Plain, China

Land subsidence caused by extensive groundwater pumping has become a factor which cannot be ignored in the sustainable exploitation of groundwater resources. The Hangzhou–Jiaxing–Huzhou Plain is one of the locations with China’s most severe land subsidence problems; the region has experienced dramatic land subsidence since the 1960s. Historical records of groundwater extraction, hydraulic head, and land subsidence show the latter to be the result of continual and excessive extraction of groundwater from deep confined aquifers. This study reconstructs land subsidence using an integrated regional groundwater flow and land subsidence model. The model is calibrated using land subsidence and groundwater level measurements from 1996 to 2007. Simulation results reproduce the cones of depression for groundwater heads and nadirs of land subsidence reasonably well. The calibrated model is used to evaluate the efficacy of land subsidence prevention plans from 2008 to 2010, and to predict future land subsidence over the next decade considering several groundwater exploitation scenarios. The results show the main cause of land subsidence to be inelastic compaction of the aquifer system resulting from continuously declining water levels. The model reveals that while the area of land subsidence will continue to extend, the rate of this extension may be significantly decreased by reduction of groundwater extraction. If the current land subsidence prevention and reclamation plans are continued and surface water diversion projects implemented, though land subsidence cannot be halted, the rate at which it is occurring can be effectively reduced.     

Reducing public participation in a formal procedure: Limits of public meetings concerning the installation of the dams of the Madeira River (Brazilian Amazon)

This article examines and discusses problems faced by proposals to increase participation by members of the public in the public debate process related to environmental policies. The analysis is based on an examination of the processes followed to develop several public meetings, which were ostensibly aimed at democratizing the process of implementing hydroelectric installations in the Madeira River in the Brazilian Amazon at the beginning of the twenty‐first century. The analysis concluded that the invitation to the public to participate in discussions regarding the construction of the dams was a mere formality. Not only did members of the public not have access to information that could have helped them understand the real social and environmental impacts of this large‐scale economic development project, but the public was restricted from interfering in its construction. As a consequence, the region is today dealing with a number of difficulties which could have been avoided if the voice of the community had been heard in the public meetings.     

Adaptation to climate change in the Northeast United States: opportunities, processes, constraints

Scientific evidence accumulating over the past decade documents that climate change impacts are already being experienced in the US Northeast. Policy-makers and resource managers must now prepare for the impacts from climate change and support implementing such plans on the ground. In this paper we argue that climate change challenges the region to maintain its economic viability, but also holds some opportunities that may enhance economic development, human well-being, and social justice. To face these challenges and seize these opportunities effectively we must better understand adaptation capacities, opportunities and constraints, the social processes of adaptation, approaches for engaging critical players and the broader public in informed debate, decision-making, and conscious interventions in the adaptation process. This paper offers a preliminary qualitative assessment, in which we emphasize the need for (1) assessing the feasibility and side effects of technological adaptation options, (2) increasing available resources and improving equitable access to them, (3) increasing institutional flexibility, fit, cooperation and decision-making authority, (4) using and enhancing human and social capital, (5) improving access to insurance and other risk-spreading mechanisms, and (6) linking scientific information more effectively to decision-makers while engaging the public. Throughout, we explore these issues through illustrative sectoral examples. We conclude with a number of principles that may guide the preparation of future adaptation plans for the Northeast.     

An integrated climate change assessment for the Northeast United States

The papers in this Special Issue are the primary technical underpinnings for the Northeast Climate Impacts Assessment (NECIA), an integrated regional-scale assessment of projected climate change, impacts and options for mitigation and adaptation across the US Northeast. The consequences of future pathways of greenhouse gas emissions on projected climate and impacts across climate-sensitive sectors is assessed by using downscaled projections from three global climate models under both higher (Alfi) and lower (B1) emissions scenarios. The findings illustrate that near-term reductions in emissions can greatly reduce the extent and severity of regionally important impacts on natural and managed ecosystems and public health in the latter half of this century, and increase the feasibility that those impacts which are now unavoidable can be successfully managed through adaptation.     

Power and Sample Size Calculations for Linear Hypotheses Associated with Mixtures of Many Components using Fixed-Ratio Ray Designs

Response surface methodology, often supported by factorial designs, is the classical experimental approach that is widely accepted for detecting and characterizing interactions among chemicals in a mixture. In an effort to reduce the experimental effort as the number of compounds under study is increased, ray designs have been proposed to study combinations of chemicals. When interest is restricted to relevant mixing ratios, we are only interested in making inference along the specific rays of interest, as opposed to methods which use designs that require more experimental effort to support the estimation of a response surface over a broader experimental region. Methods have been developed for the test of additivity along multiple fixed-ratio rays. Of primary importance is the detection of interactions with reasonable power. The objective of this paper is to address power and sample size issues related to the hypothesis of no interaction.     

Validating the enchytraeid reproduction test: organisation and results of an international ringtest

In this paper the experiences concerning the organisation and results of the enchytraeid reproduction test (ERT) ringtest are summarised (for details see J. R?mbke, T. Moser, Organisation and Performance of an International Ringtest for the Validation of the Enchytraeid Reproduction Test, vols. I and II. UBA-Texte 4/99, 1999, 150, 223 pp). The performance of this ringtest was in line with requirements published by OECD. It was sponsored by the German Federal Environmental Agency (Umweltbundesamt; UBA, Berlin). The UBA was also actively engaged (together with the European Chemicals Bureau, Ispra) in a scientific task force, which consisted of seven scientists experienced in terrestrial ecology and ecotoxicology. 29 institutions (mainly from universities and contract research laboratories) from 15 countries of Europe and North America participated actively in the ringtest. The co-ordinating laboratory centrally distributed the test chemicals, guidance papers and test organisms to all participants. In addition, several training courses were organised. Most participants performed two tests with the fungicide Carbendazim and two with 4-nitrophenol. For each chemical, one test was designed according to an ECx approach and the other according to an NOEC approach. Several aspects of the test protocol were modified based on the experiences gained during the ringtest. A major aspect of the project was the detailed statistical evaluation of the test results (for details see A. Weyers, J. R?mbke, T. Moser, T. Ratte, Results of and statistical implications from the enchytraeid reproduction ringtest, 2001, submitted), leading to recommendations for an optimised ecotoxicological test design. A total of 92 tests were performed according to the protocol which is among the highest number ever performed in a ringtest. About 72% met the validity criteria (control mortality < 20%, > 25 juveniles per 10 adults). The effects of the two test chemicals on enchytraeid reproduction were in the range expected from data in the literature on oligochaete toxicity. However, statistical evaluation of the data was sometimes difficult as a result of the high variability in the number of juveniles. This variability was caused by several reasons, including hormesis effects or lack of experience of some participants. Comparison of the data from the NOEC and ECx approaches pointed to a clear advantage in favour of the latter. In most cases EC10 values were lower than the NOEC values determined in the same test. For details see A. Weyers et al. (loc. cit.). Reproducibility of the test data and practicability of the ERT ringtest were of the same order of magnitude as other ringtests recently performed. As a result of the ringtest, the ERT draft guideline was significantly improved. The new version is currently being standardised by OECD, ISO and ASTM.     

Determination of polychlorinated dibenzo-p-dioxins and dibenzo-furans in solid residues from wood combustion by HRGC/HRMS

PCDD/PCDF were determined in solid samples from wood combustion. The samples included grate ashes, bottom ashes, furnace ashes as well as fly and cyclone ashes. The solid waste samples were classified into bottom and fly ash from native wood and bottom and fly ash from waste wood. For each of the four classes concentration distribution patterns from individual congeners, the sums of PCDD/PCDF and the international toxicity equivalents (I-TEQ) values are given. The I-TEQ levels of fly ash from waste wood burning can be approximately up to two thousand times higher than the values from fly ashes of natural wood. The I-TEQ levels in bottom ashes from waste wood combustion systems are as low as the corresponding ashes from the combustion of native wood. Grate ash samples from waste wood combustion systems with low carbon burnout show high levels of PCDD/PCDF.