Protective effect of Spirulina platensis against aluminium-induced nephrotoxicity and DNA damage in rats

The protective effect of Spirulina platensis (SP) powder against aluminium-induced nephrotoxicity and DNA damage in rats was studied. Male rats receiving daily 40 mg/kg b.wt. aluminium chloride (AlCl₃) orally had increased serum levels of urea and creatinine, up regulated kidney injury molecule-1 and tissue inhibitor of metalloproteinase-1 genes, down regulated catalase and glutathione peroxidase genes, and increased all parameters of kidney DNA damage using comet assay. Treatment with SP alleviated all AlCl₃-induced effects of toxicity, especially when the animals were pre-treated.     

Enhancement of the daily performance of solar still by exhaust gases under hot and cold climate conditions

Environmental Science and Pollution Research - A study is presented on the enhancement of solar still (SS) performance by using chimney exhaust gases (EGs) passing through chimney channels under...     

Binding of aluminum to human serum transferrin,human serum albumin and rat serum proteins

Abstract

Human serum transferrin (HSTF), human serum albumin (HSA) and rat serum were compared for their interaction with AlCl₃ , in a Tris‐HCl buffer solutions (pH 7.4). The AlCl₃ was tested in series of concentrations in the range of 50 μM up to 500 μM . HSTF, HSA and their 1:1 mixture and rat serum were incubated at 37°C with series of AlCl₃ concentrations. The protein profile of the incubated solutions were compared to control using SDS‐PAGE and FPLC tests. The results indicated that HSTF was more specifically responsive to AlCl₃showing a characteristic increase in its UV absorption, peak and area dimensions. Simultaneously, HSA was less affected, but it showed a significant shift with an increase in molecular weight accompanied with a change in its profile. The respective bands of transferrin and albumin in rat serum behaved similarly. The SDS‐PAGE and FPLC data coincided and confirmed the preferential affinity of HSTF to bind with Al³⁺ . These results support the suggestion of using HSTF for monitoring levels of Al³⁺ in human blood samples of exposed population. The importance of further developing such a biomarker is the increased demand for early detection of the hazardous levels of Al³⁺ in relation to its long term neurotoxic adverse effects.     

A comparative study of the length-weight equation and the condition factor of Tilapia zillii from Lake Mariut,Egypt

The length-weight relationship of Tilapia zillii Gerv., seasonally collected from Lake Mariut (a brackish-water lake), Egypt, has been studied. It was found that mature fishes are fatter than spent individuals, and that this mainly affects the exponent n (W=a L ⁿ). While the females are nearly of equal fatness to the males, a higher value of the exponent n is recorded for the females; this is due to the higher weight of the gonads. The smaller fish are more fecundite than the larger, elder individuals; this is revealed by comparison of the condition factor K and GSI (gonadosomatic index) for ripo and spent fish, respectively.     

Groundwater-dependent irrigation costs and benefits for adaptation to global change

The effects of a 1.5 °C global change on irrigation costs and carbon emissions in a groundwater-dependent irrigation system were assessed in the northwestern region of Bangladesh and examined at the global scale to determine possible global impacts and propose necessary adaptation measures. Downscaled climate projections were obtained from an ensemble of eight general circulation models (GCMs) for three representative concentration pathways (RCPs), RCP2.6, RCP4.5, and RCP8.5 and were used to generate the 1.5 °C warming scenarios. A water balance model was used to estimate irrigation demand, a support vector machine (SVM) model was used to simulate groundwater levels, an energy-use model was used to estimate carbon emissions from the irrigation pump, and a multiple linear regression (MLR) model was used to simulate the irrigation costs. The results showed that groundwater levels would likely drop by only 0.03 to 0.4 m under a 1.5 °C temperature increase, which would result in an increase in irrigation costs and carbon emissions ranging from 11.14 to 148.4 Bangladesh taka (BDT) and 0.3 to 4% CO₂ emissions/ha, respectively, in northwestern Bangladesh. The results indicate that the impacts of climate change on irrigation costs for groundwater-dependent irrigation would be negligible if warming is limited to 1.5 °C; however, increased emissions, up to 4%, from irrigation pumps can have a significant impact on the total emissions from agriculture. This study revealed that similar impacts from irrigation pumps worldwide would result in an increase in carbon emissions by 4.65 to 65.06 thousand tons, based only on emissions from groundwater-dependent rice fields. Restricting groundwater-based irrigation in regions where the groundwater is already vulnerable, improving irrigation efficiency by educating farmers and enhancing pump efficiency by following optimum pumping guidelines can mitigate the impacts of climate change on groundwater resources, increase farmers’ profits, and reduce carbon emissions in regions with groundwater-dependent irrigation.     

Repeatability and heritability of sperm competition outcomes in males and females of <Emphasis Type="Italic">Tribolium castaneum</Emphasis>

Differences among males in their success in achieving fertilisations when females mate with more than one partner are now recognised as an important target of sexual selection. However, very few studies have attempted to determine whether particular males are consistently successful in sperm competition and whether success in sperm competition is a heritable trait. Additionally, the potential heritability of female traits that influence the outcome of sperm competition has received only limited attention. Using the polyandrous beetle Tribolium castaneum, we examined repeatability of male success in sperm competition by mating pairs of males carrying different visible genetic markers to a string of different females. Males showed consistency in their ability to successfully transfer sperm to females, but not in their success in sperm competition. Furthermore, when we independently compared success in sperm competition of fathers with their sons, we found no evidence for heritability of this trait. Similarly, females that exhibited high or low first male sperm precedence did not tend to have daughters that showed the same pattern. Our results suggest that we should be wary of assuming that success in sperm competition is heritable through either sex.     

Assessment of the role of thymol in combating chromium (VI)-induced oxidative stress in isolated rat erythrocytes in vitro

Thymol, the main phenolic compound in Thymus vulgaris, has been shown to have various biological effects. The main objective of this study was to investigate the efficacy of thymol on counteracting hexavalent chromium-induced oxidative damage in rat erythrocytes in vitro. The radical scavenging activity of thymol was examined using the 1, 1-diphenyl-2-picrylhydrazyl assay. Erythrocytes resistance to oxidative damage, lipid peroxidation, osmotic pressure, hemolysis as well as morphological alterations were evaluated in the presence of 2.5 µg thymol mL^?1 with or without 5 µmol hexavalent chromium mL^?1 of the incubation media. Results from the 1,1-diphenyl-2-picrylhydrazyl assay denoted good radical scavenging activity of thymol. Thymol caused a significant increase in superoxide dismutase and catalase activities and reduced glutathione content in erythrocytes intoxicated with hexavalent chromium. In contrast, the presence of thymol resulted in markedly less-elevated malondialdehyde levels, hemolysis, and destabilization of erythrocytes exposed to hexavalent chromium. Microscopically, thymol markedly reduced hexavalent chromium-induced morphological alterations in rat red blood cells. Conclusively, thymol counteracted hexavalent chromium-induced oxidative damage in rat erythrocytes.     

Health care system hazard vulnerability analysis: an assessment of all public hospitals in Abu Dhabi

Hazard vulnerability analysis (HVA) is used to risk‐stratify potential threats, measure the probability of those threats, and guide disaster preparedness. The primary objective of this project was to analyse the level of disaster preparedness in public hospitals in the Emirate of Abu Dhabi, utilising the HVA tool in collaboration with the Disaster Medicine Section at Harvard Medical School. The secondary objective was to review each facility's disaster plan and make recommendations based on the HVA findings. Based on the review, this article makes eight observations, including on the need for more accurate data; better hazard assessment capabilities; enhanced decontamination capacities; and the development of hospital‐specific emergency management programmes, a hospital incident command system, and a centralised, dedicated regional disaster coordination centre. With this project, HVAs were conducted successfully for the first time in health care facilities in Abu Dhabi. This study thus serves as another successful example of multidisciplinary emergency preparedness processes.     

Effect of dietary phytogenics (herbal mixture) supplementation on growth performance,nutrient utilization,antioxidative properties,and immune response in broilers

Environmental Science and Pollution Research - This experiment was conducted to study that effect of a phytogenics (herbal mixture) supplementation as alternative to antibiotics on the growth...