Pediatric pedestrian trauma study: a pilot project

OBJECTIVE: To evaluate the implementation of the WalkSafe Program, a school based educational injury prevention program for children grades Kindergarten through 5. METHODS: A randomized comparative design was used for this study. The study was conducted in two high-risk urban school districts, which were chosen based on the geographic areas with the highest pedestrian injury and fatality rates. Four elementary schools (two in each district) were identified as potential study sites. Two intervention schools, one in each school district, were randomly chosen to receive the WalkSafe program; the other two schools served as controls, and received no intervention. The data was collected within the classroom setting for both the intervention and control schools. All elementary school children were administered the same pedestrian safety questionnaire as a pre-test, post-test and at three months following the intervention. RESULTS: A total of 2300 children participated in the WalkSafe program. The intervention (I) schools showed significant improvement in post-test scores then the control (C) schools (p = 0.012), and the (I) schools were able to maintain their test scores as reflected in a three-month follow-up evaluation (p = 0.47). Grades 3-5 of the (I) schools showed significant improvement in their test scores over grades K-2 (p < 0.0001). CONCLUSION: The WalkSafe program was shown to improve the pedestrian safety knowledge of elementary school children. Future research will include implementing the WalkSafe program at each elementary school within a single high-risk district.     

Outdoor versus indoor contributions to indoor particulate matter (PM) determined by mass balance methods

This study compares an indoor-outdoor air-exchange mass balance model (IO model) with a chemical mass balance (CMB) model. The models were used to determine the contribution of outdoor sources and indoor resuspension activities to indoor particulate matter (PM) concentrations. Simultaneous indoor and outdoor measurements of PM concentration, chemical composition, and air-exchange rate were made for five consecutive days at a single-family residence using particle counters, nephelometers, and filter samples of integrated PM with an aerodynamic diameter of less than or equal to 2.5 microm (PM2.5) and PM with an aerodynamic diameter of less than or equal to 5 microm (PM5). Chemical compositions were determined by inductively coupled plasma mass-spectrometry. During three high-activity days, prescribed activities, such as cleaning and walking, were conducted over a period of 4-6 hr. For the remaining two days, indoor activities were minimal. Indoor sources accounted for 60-89% of the PM2.5 and more than 90% of the PM5 for the high-activity days. For the minimal-activity days, indoor sources accounted for 27-47% of PM2.5 and 44-60% of the PM5. Good agreement was found between the two mass balance methods. Indoor PM2.5 originating outdoors averaged 53% of outdoor concentrations.     

Second trimester maternal serum analytes in triploid pregnancies: correlation with phenotype and sex chromosome complement

Second trimester maternal serum alpha-fetoprotein (MS-AFP), human chorionic gonadotrophin (hCG), unconjugated estiol (uE3), and inhibin-A (INH-A) levels were evaluated in pregnancies complicated by triploidy. In addition to seven new triploid pregnancies, the results for 67 published cases were reviewed. All cases appear to fall into two major groups. First, those identifiable as screen-positive for both Down syndrome and an open neural tube defect (ONTD) with elevated MS-AFP, grossly elevated hCG, low/normal uE3, and probably elevated INH-A. Pregnancies in the second group are identifiable as screen-positive for trisomy 18 with low/normal MS-AFP, and very low hCG, uE3 and INH-A. Triploid pregnancies with high maternal serum hCG nearly always show a placenta with partial mole (25/27 or 93%), a high frequency of ONTDs or ventral wall defects (VWDs) (8/28 or 29%) and have either an XXX or XXY karyotype (observed ratio 6:10, respectively). Low hCG is infrequently associated with a molar placenta (1/11 or 9%), does not appear to be associated with ONTDs or VWDs (0/29 or 0%), and shows an excess of XXX over XXY karyotypes (observed ratio 17:2). There were 16 cases with either a molar placenta, an ONTD or a VWD that received the MS-AFP and hCG tests. All 16 were screen-positive for an ONTD (MS-AFP≥2 multiples of the median). In addition, all 31 cases that received MS-AFP, hCG, uE3 (and where available INH-A) were screen-positive for either Down syndrome or trisomy 18. The findings are discussed in the context of expected differences between digynic and diandric triploidy. It is suggested that the sex chromosome complement in triploidy is an important factor in determining risk for partial mole development and in utero survival. Copyright © 2001 John Wiley & Sons, Ltd.     

Local vulnerability as an advantage: mangrove forest management in Pará state,north Brazil,under conditions of illegality

When ecosystems are threatened or scientific knowledge of the effects of human action is uncertain, legislative prohibition is often adopted. This paper examines how the criminalization of mangrove tree use affects ecosystem management outcomes. We explore the biological, economic and social sustainability effects of the legal ban on mangrove use on the coast of Bragança, Pará, north Brazil. There are two main categories of mangrove users in this area: firstly, local subsistence users who also derive some financial incomes from mangrove sale. Their mangrove use is intertwined with household livelihood strategies and they display self-initiated planning and action towards sustainable management; secondly, more mobile, purely commercial users who are responsible for most commercial mangrove exploitation and who employ regionally sequential, predatory resource exploitation strategies. These users are typically based at some distance from the exploited areas and share neither local livelihood strategies nor sustainability agendas. The current outright ban on any utilization of mangrove flora seems to undermine biological sustainability, is economically inefficient and generates normative insecurity, conflict and social polarization. The ineffectiveness of the outright legal prohibition of mangrove tree use in terms of sustainable coastal management leads us to investigate alternative management options. We suggest that the legalization of local mangrove utilization and the strengthening of local users rights and responsibilities to control outsiders in a co-management framework, as proposed in the Brazilian extractive reserves (RESEX) approach, is most likely to advance ecologically, economically and socially sustainable mangrove management. It is demonstrated that a legal recognition of local entitlements to mangrove trees would reduce social vulnerability and therefore move forest management outcomes into more desirable directions.

Introduced species and management of a Nothofagus/Austrocedrus forest

Isla Victoria (Nahuel Huapi National Park, Argentina), a large island dominated by native Nothofagus and Austrocedrus forest, has old plantations of many introduced tree species, some of which are famed invaders of native ecosystems elsewhere. There are also large populations of introduced deer and shrubs that may interact in a complex way with the introduced trees, as well as a recently arrived population of wild boar. Long-standing concern that the introduced trees will invade and transform native forest may be unwarranted, as there is little evidence of progressive invasion, even close to the plantations, despite over 50 years of opportunity. Introduced and native shrubs allow scattered introduced trees to achieve substantial size in abandoned pastures, but in almost all areas neither the trees nor the shrubs appear to be spreading beyond these sites. These shrub communities may be stable rather than successional, but the technology for restoring them to native forest is uncertain and probably currently impractical. Any attempt to remove the exotic tree seedlings and saplings from native forest would probably create the very conditions that would favor colonization by exotic plants rather than native trees, while simply clear-cutting the plantations would be unlikely to lead to regeneration of Nothofagus or Austrocedrus. The key to maintaining native forest is preventing catastrophic fire, as several introduced trees and shrubs would be favored over native dominant trees in recolonization. Deer undoubtedly interact with both native and introduced trees and shrubs, but their net effect on native forest is not yet clear, and specific management of deer beyond the current hunting by staff is unwarranted, at least if preventing tree invasion is the goal. The steep terrain and shallow soil make the recently arrived boar a grave threat to the native forest. Eradication is probably feasible and should be attempted quickly.     

Evaluation of an Infiltration Best Management Practice Utilizing Pervious Concrete1

Abstract: A pervious concrete infiltration basin was installed on the campus of Villanova University in August 2002. A study was undertaken to determine what contaminants, if any, were introduced to the soils underlying the site as a result of this best management practice (BMP). The average infiltration rate at the site is approximately 10^?4 cm/s. The drainage area (5,208 m²) consists of grassy surfaces (36%), standard concrete/asphalt (30%), and roof surfaces (30%) that directly connect to the infiltration beds via downspouts and storm sewers. Composite samples of infiltrated stormwater were collected from the vadose zone using soil moisture suction devices. Discrete samples were collected from a port within an infiltration bed and a downspout from a roof surface. Samples from 17 storms were analyzed for pH, conductivity, and concentrations of suspended solids, dissolved solids, chloride, copper, and total nitrogen. Copper and chloride were the two constituents of concern at this site. Copper was introduced to the system from the roof, while chloride was introduced from deicing practices. Copper was not found in porewater beneath 0.3 m and the chloride was not significant enough to impact the ground water. This research indicates that with proper siting, an infiltration BMP will not adversely impact the ground water.     

Hepatitis A Virus: State of the Art

Hepatitis A is the most common among all hepatitis worldwide in spite of an efficient vaccine and improved hygiene. Shellfish-borne outbreaks are still of major concern causing hundreds of cases and huge economical losses in the present context of global food trade. Hepatitis A virus (HAV) is a unique picornavirus with many differences in its molecular biology including both its incapacity to induce the inhibition of the cellular protein synthesis and a highly biased and deoptimized codon usage with respect the cell. The final goal of this intriguing strategy seems to be the need for a fine-tuning control of the translation kinetics, particularly at the capsid coding region, and the underlying mechanism is the use of a right combination of common and rare codons to allow a regulated ribosome traffic rate thus ensuring the proper protein folding. Capsid folding is critical to warrant a high environmental stability for a virus transmitted through the fecal–oral route with long extracorporeal periods.     

On international equity in reducing emissions from deforestation

Reducing emissions from deforestation and forest degradation (REDD) can be an effective and efficient means of mitigating climate change. However, the perceived equity in the distribution of financial incentives for REDD could also emerge as a critical issue in international negotiations. The design of reference levels, which provide the benchmark for crediting emissions reductions, affects the economic incentives for national participation in a REDD mechanism and thus the overall willingness to reach an agreement on REDD. This paper compares the equity impacts of five proposed reference level designs using a partial-equilibrium model. Tradeoffs among equity, environmental effectiveness and cost-efficiency indicate the proposals trigger similar aggregate emissions reductions but lead to different outcomes in efficiency and alternative measures of equity. If equity across countries is measured as the financial incentive provided relative to a country's forest carbon stock, then a REDD mechanism compensating a uniform share of at-risk carbon stocks is the most equitable. On the other hand, if equity is evaluated as the financial incentive relative to the opportunity costs of participating in REDD, then the most equitable approach would be compensating emissions reductions but withholding a part of the payments to compensate for carbon stocks, which also encourages broader country participation under our model.     

Ovarian fluid of receptive females enhances sperm velocity

The females of several internal fertilizers are able to store sperm for a long time, reducing the risk of sperm limitation. However, it also means that males can attempt to mate outside females’ receptive period, potentially increasing the level of sperm competition and exacerbating sexual conflict over mating. The guppy (Poecilia reticulata), an internally fertilizing fish, is a model system of such competition and conflict. Female guppies accept courtship and mate consensually only during receptive periods of the ovarian cycle but receive approximately one (mostly forced) mating attempt per minute both during and outside their sexually receptive phase. In addition, females can store viable sperm for months. We expected that guppy females would disfavour sperm received during their unreceptive period, possibly by modulating the quality and/or quantity of the components present in the ovarian fluid (OF) over the breeding cycle. Ovarian fluid has been shown to affect sperm velocity, a determinant of sperm competition success in this and other fishes. We found that in vitro sperm velocity is slower in OF collected from unreceptive females than in OF from receptive females. Visual stimulation with a potential partner prior to collection did not significantly affect in vitro sperm velocity. These results suggest that sperm received by unreceptive females may be disfavoured as sperm velocity likely affects the migration process and the number of sperm that reach storage sites.     

Metacommunity organization of soil microorganisms depends on habitat defined by presence of Lobelia siphilitica plants

We tested regional-scale spatial patterns in soil microbial community composition for agreement with species sorting and dispersal limitation, two alternative mechanisms behind different models of metacommunity organization. Furthermore, we tested whether regional metacommunity organization depends on local habitat type. We sampled from sites across Ohio and West Virginia hosting populations of Lobelia siphilitica, and compared the metacommunity organization of soil microbial communities under L. siphilitica to those in adjacent areas at each site. In the absence of L. siphilitica, bacterial community composition across the region was consistent with species sorting. However, under L. siphilitica, bacterial community composition was consistent with dispersal limitation. Fungal community composition remained largely unexplained, although fungal communities under L. siphilitica were both significantly different in composition and less variable in composition than in adjacent areas. Our results show that communities in different local habitat types (e.g., in the presence or absence of a particular plant) may be structured on a regional scale by different processes, despite being separated by only centimeters at the local scale.