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101.
102.
This study was designed to determine the protective effects of zinc (Zn) using liver marker enzymes in the serum and liver along with hepatic elemental profile in lead (Pb)-treated protein-deficient (PD) Sprague–Dawley male rats. Zn in the form of zinc sulfate at a dose of 227?mg?L?1 in drinking water was administrated to control, PD as well as Pb-treated PD rats for 8 weeks. Pb treatment was given orally as lead acetate at a dose level of 100?mg?kg?1 body weight to control and PD rats. The effects of different treatments were studied on the activities of enzymes that included alkaline phosphatase (ALP), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in serum. The status of different elements (Cl, K, Mn, Fe, Cu, Zn, Se, Rb, Pb) in liver was also studied. Rats given PD diet and Pb showed significant inhibition in serum ALP activity associated with significant elevation in both AST and ALT activities. Serum ALP activity showed a significant inhibition week 1 until week 8 in Pb-treated PD rats. In contrast, serum AST activity was elevated both at 3 and 8 weeks while serum ALT activity was elevated at 8 weeks in Pb-treated PD rats. Pb treatment to PD rats elevated hepatic ALP, AST and ALT activities but depressed hepatic AST. Zn supplementation to Pb-treated PD rats restored the altered enzyme activities. The levels of K, Fe, Cu, Zn, Se and Rb were altered in protein deficiency. Furthermore, treatment with Pb to these animals depressed the Cu levels. Zn treatment to Pb-treated PD animals tended to restore the levels of altered elements. Hence, the present study clearly suggests that Zn plays an important role in regulating the liver marker enzymes and essential elements under conditions of Pb toxicity and protein deficiency. 相似文献
103.
Kumar Pankaj Mishra Vandana Yadav Shalu Yadav Archana Garg Shafali Poria Pankaj Farooqi Furqan Dumée Ludovic F. Sharma Radhey Shyam 《Environmental science and pollution research international》2022,29(40):60212-60231
Environmental Science and Pollution Research - A sectorial approach for assessing heavy metal pollution in rivers neglects the inter-relationship between its environmental compartments and thus... 相似文献
104.
Goyal Shivam Garg Dixit Luthra Sunil 《Environment, Development and Sustainability》2022,24(4):5195-5224
Environment, Development and Sustainability - Scarcity of natural resources and increasing level of pollution have put the survival of human in trouble. This situation has compelled the world to... 相似文献
105.
Ali Anwer Garg Utsav Khan Kashif Ullah Azim Yasser 《Journal of Polymers and the Environment》2022,30(10):4435-4451
Journal of Polymers and the Environment - The synthesis of an efficient catalytic system with a safe catalysis approach has always been the concern of researchers to eradicate the problems arising... 相似文献
106.
Kalita Biman Baruah Anupal J. Handique Anurag Sarma Arup Kumar 《Environmental Fluid Mechanics》2022,22(4):743-761
Environmental Fluid Mechanics - Mixing layers and associated large-scale turbulent structures are some of the most common features of turbulent shallow water flow. Due to their... 相似文献