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221.
Ahmed T Pathak R Mustafa MD Kar R Tripathi AK Ahmed RS Banerjee BD 《Environmental monitoring and assessment》2011,179(1-4):293-299
Endosulfan, malathion, and phosphamidon are widely used pesticides. Subchronic exposure to these contaminants commonly affects the central nervous system, immune, gastrointestinal, renal, and reproductive system. There effects have been attributed to increased oxidative stress. This study was conducted to examine the role of oxidative stress in genotoxicity following pesticide exposure using peripheral blood mononuclear cells (PBMC) in vitro. Further possible attenuation of genotoxicity was studied using N-acetylcysteine (NAC) and curcumin as known modulators of oxidative stress. Cultured mononuclear cells was isolated from peripheral blood of healthy volunteers, and exposed to varying concentrations of different pesticides: endosulfan, malathion, and phosphamidon for 6, 12, and 24 h. Lipid peroxidation was assessed by cellular malondialdehyde (MDA) level and DNA damage was quantified by measuring 8-hydroxy-2'-deoxyguanosine (8-OH-dG) using ELISA. Both MDA and 8-OH-dG were significantly increased in a dose-dependent manner following treatment with these pesticides. There was a significant decrease in MDA and 8-OH-dG levels in PBMC when co-treated with NAC or/and curcumin as compared to pesticide alone. These results indicate that pesticide-induced oxidative stress is probably responsible for the DNA damage, and NAC or curcumin attenuate this effect by counteracting the oxidative stress. 相似文献
222.
Gur Cihan Kandemir Fatih Mehmet Darendelioglu Ekrem Caglayan Cuneyt Kucukler Sefa Kandemir Ozge Ileriturk Mustafa 《Environmental science and pollution research international》2021,28(36):49808-49819
Environmental Science and Pollution Research - The presented study investigates the effects of morin against toxicity induced by acrylamide (ACR) in the brains of Sprague Dawley rats. In this... 相似文献
223.
Assar Doaa H. Asa Samah Abou El-Abasy Moshira A. Elbialy Zizy I. Shukry Mustafa Latif Amera Abd El BinMowyna Mona N. Althobaiti Norah A. El-Magd Mohammed A. 《Environmental science and pollution research international》2022,29(46):69798-69817
Environmental Science and Pollution Research - Ochratoxin A (OTA) is one of the most dangerous and that pollute agricultural products, inducing a variety of toxic effects in humans and animals. The... 相似文献
224.
Pekdemir Sibel Özen Öner Ecem Pekdemir Mustafa Ersin Dalkılıç Semih Kadıoğlu Dalkılıç Lütfiye 《Journal of Polymers and the Environment》2022,30(9):3645-3655
Journal of Polymers and the Environment - Poly ε-caprolactone (PCL) synthesized by ring-opening polymerization method, and then it blended with polylactic acid (PLA). The blend was loaded with... 相似文献
225.
Cemile Temur Osman Tiryaki Oguzhan Uzun Mustafa Basaran 《Journal of environmental science and health. Part. B》2013,48(9):842-850
This study was carried out to develop and validate a reliable analytical procedure for trifluralin analysis in wind-eroded sediments. Soil sediments trapped in BEST sediment traps were subjected to QuEChERS extraction method, incorporating a simple simultaneous cleanup step, followed by trifluralin analysis with GC-ECD. Results revealed that QuEChERS method offered a potential alternative technique for pesticide extraction from soil samples. The validity of analytical method was performed by the method-performance criteria such as, recovery, LOD, LOQ repeatability, precision, and all found to be within the required limits. It was also observed in this study that herbicide concentrations in the wind-eroded sediment did not vary with the time and trap height. Trifluralin concentrations of surface soil after four erosion events were higher (626.05 μg/kg) than wind-eroded soil (450.08 μg/kg). 相似文献
226.
Mehmet Tufekci Volkan Numan Bulut Hamide Elvan Duygu Ozdes Mustafa Soylak Celal Duran 《Environmental monitoring and assessment》2013,185(2):1107-1115
A new, simple, and rapid separation and preconcentration procedure, for determination of Pb(II), Cd(II), Zn(II), and Co(II) ions in environmental real samples, has been developed. The method is based on the combination of coprecipitation of analyte ions by the aid of the Mo(VI)–diethyldithiocarbamate–(Mo(VI)-DDTC) precipitate and flame atomic absorption spectrometric determinations. The effects of experimental conditions like pH of the aqueous solution, amounts of DDTC and Mo(VI), standing time, centrifugation rate and time, sample volume, etc. and also the influences of some foreign ions were investigated in detail on the quantitative recoveries of the analyte ions. The preconcentration factors were found to be 150 for Pb(II), Zn(II) and Co(II), and 200 for Cd(II) ions. The detection limits were in the range of 0.1–2.2 μg L?1 while the relative standard deviations were found to be lower than 5 % for the studied analyte ions. The accuracy of the method was checked by spiked/recovery tests and the analysis of certified reference material (CRM TMDW-500 Drinking Water). The procedure was successfully applied to seawater and stream water as liquid samples and baby food and dried eggplant as solid samples in order to determine the levels of Pb(II), Cd(II), Zn(II), and Co(II) ions. 相似文献