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71.
We report a multiplex family with a GATA1 gene mutation responsible for a massive fetal cerebral hemorrhage occurring at 36 weeks. Two other stillbirth cousins presented with fetal hydrops and congenital hemochromatosis' phenotype at 37 and 12 weeks of gestation. Molecular screening revealed the presence of a c.613G>A pathogenic allelic variation in exon 4 of GATA1 gene in the 3 male siblings and their carrier mothers. The diagnosis of a GATA1 gene mutation may be suspected in cases of male fetuses with intracerebral bleeding, particularly if a history of prior fetal loss(es) and mild maternal thrombocytopenia are also present.  相似文献   
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Environmental Science and Pollution Research - The port regions of the Amazon are subject to environmental impacts high shipping traffic. In October 2015, a cargo ship containing 5000 oxen sank in...  相似文献   
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Environmental Science and Pollution Research - This research aimed to determine the water-sediment interaction (partition coefficient Kd) of trace element (Cd, Cu, total Cr, Pb, and Zn) in tropical...  相似文献   
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In spite of increasing annual expenditures for flood control, losses from flooding continue to rise in the United States. This seeming contradiction arises from overdependence on federally supported structural solutions to flood problems. Nonstructural controls are initiated reluctantly at local levels of government because of constitutional questions, restrictions of local tax bases, lack of federal subsidies for nonstructural solutions, and the high costs of delineating flood hazard areas. The success of the National Flood Insurance Program is doubtful since only about five percent of the flood-prone communities in the United States have qualified for the regular program. Future reduction of flood losses is dependent upon increasing popular awareness of flood hazards and altering federal subsidy policies to reduce the impact of local land-use regulations.  相似文献   
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The present work presents the results of 137Cs concentration in seawater, fish and sediments samples collect in 11 sampling points, crossing the Brazilian Southeastern coastal region, from Vitória (ES) to Santos (SP), on a routine basis from 1997 to 2002. This monitoring program was carried out by the Instituto de Radioproteção e Dosimetria (IRD/CNEN/MCT), in cooperation with the Instituto de Estudos do Mar Almirante Paulo Moreira (IEAPM/Brazilian Navy), aiming at determining artificial radionuclides in marine samples. Additionally to the 137Cs results, 90Sr concentrations in fish samples from 1998 to 2002 are also reported.The 137Cs in seawater follows a lognormal distribution, with a geometric mean of 1.8 Bq m-3 and a geometric standard deviation of 1.4 (n=54), decay corrected to June/2002. For 137Cs levels in fish samples a geometric mean of 0.19 Bq kg−1 and a geometric standard deviation of 2.9 (n=39), decay corrected to June/2002, with a range of 0.03 to 1.7 Bq kg−1, were obtained. Based on the 137Cs mean concentration in fish as well as in seawater, a transfer factor of 1 × 102 was calculated, which is quite in agreement with the recommended value found in the Safety Report Serie 19.  相似文献   
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