Effects of early developmental conditions on innate immunity are only evident under favourable adult conditions in zebra finches

Long-term effects of unfavourable conditions during development can be expected to depend on the quality of the environment experienced by the same individuals during adulthood. Yet, in the majority of studies, long-term effects of early developmental conditions have been assessed under favourable adult conditions only. The immune system might be particularly vulnerable to early environmental conditions as its development, maintenance and use are thought to be energetically costly. Here, we studied the interactive effects of favourable and unfavourable conditions during nestling and adult stages on innate immunity (lysis and agglutination scores) of captive male and female zebra finches (Taeniopygia guttata). Nestling environmental conditions were manipulated by a brood size experiment, while a foraging cost treatment was imposed on the same individuals during adulthood. This combined treatment showed that innate immunity of adult zebra finches is affected by their early developmental conditions and varies between both sexes. Lysis scores, but not agglutination scores, were higher in individuals raised in small broods and in males. However, these effects were only present in birds that experienced low foraging costs. This study shows that the quality of the adult environment may shape the long-term consequences of early developmental conditions on innate immunity, as long-term effects of nestling environment were only evident under favourable adult conditions.     

温度和氯离子浓度对30CrMnSiNiA腐蚀速率的影响研究

目的研究温度和氯离子浓度对金属腐蚀速率的影响。方法通过失重法研究对比30CrMnSiNiA结构钢在不同氯离子浓度和温度下的腐蚀速率。结果 30CrMnSiNiA钢的腐蚀速率都经历了一个增大-减小-趋于稳定的过程,说明腐蚀机理并未发生改变。在温度较低和氯离子浓度较低的条件下,升高温度和氯离子浓度将会提高腐蚀速率;当温度和氯离子浓度很高时,继续升高温度和氯离子浓度将会降低溶液中溶解氧的含量,使腐蚀速率降低,溶解氧的极限扩展速率将会成为限制腐蚀速率的关键因素。结论不同温度和氯离子浓度下金属腐蚀规律相同,温度和氯离子浓度在一定范围内促进了金属的腐蚀速率。当超过转化点后,提高温度和氯离子浓度会降低腐蚀速率。     

城乡融合评价研究综述：内涵辨识、理论认知与体系重构

科学的城乡融合评价是城乡融合工作的重要环节,是建立健全城乡融合体制机制的基础。以“内涵辨识—理论认知—体系重构”为逻辑主线,从城乡融合的概念内涵、基础理论、评价指标、评价方法、评价尺度及演化机理等方面,开展城乡融合评价综述。研究表明：学界对城乡融合概念与内涵的认识基本一致,且已有一定理论基础;城乡融合评价指标选取呈现多维化、多属性化特征,但指标体系构建尚未突破静态性层面;定量评价方法较为单一;研究尺度整体偏向中宏观,缺少微观视角下的量化以及不同融合模式对比研究;城乡融合的时空分异格局及其机理研究亟待进一步深化。对此,提出了以下五点展望：（1）加强基础理论体系建设,完善系统研究框架构建;（2）优化多维评价指标体系,识别城乡融合发展模式;（3）深化城乡要素流动机制,推动城乡空间均衡发展;（4）加强微观尺度细节挖掘,健全城乡融合推进机制;（5）强化数字经济赋能作用,创新城乡高质量融合发展机制。