Chorionic villus sampling utilization following reports of a possible association with fetal limb defects

Prenatal diagnosis choices were reviewed in 473 women who presented for genetic counselling prior to 11 weeks' gestation for the indication of advanced maternal age. Group A consisted of 336 patients who were unaware of a possible association between chorionic villus sampling (CVS) and limb defects. Group B consisted of 137 patients who were provided this information. Fifty-one per cent of patients in group A and 45 per cent of patients in group B chose CVS. This difference was not significant by χ² analysis (P = 0·7). Patterns of prenatal diagnosis procedure utilization from 1987 to 1992 revealed a significant reduction in CVS utilization accompanied by a corresponding increase in amniocentesis after the association between CVS and limb defects was publicized. Referrals for CVS counselling also significantly declined. However, acceptance rates did not change for those patients who received genetic counselling. First-trimester genetic counselling, including a discussion regarding a possible association between CVS and limb defects, helps patients make informed decisions concerning prenatal diagnosis options, and, in our population, resulted in no change in CVS acceptance rates.     

Effect of weirs on sediment deposition in Louisiana coastal marshes

Sediment deposition both inside and outside of fixed-crest weirs was measured for fresh/intermediate, brackish, and saline marsh areas in coastal Louisiana, USA. Sediment traps, collected on a weekly basis, were used to monitor short-term changes in sediment deposition. Feldspar marker horizons were used to measure cumulative marsh accretion during the 16-week monitoring period. Results show that for most sites less sediment is deposited in marsh behind weirs than at the control sites outside the weirs. Patterns at each site are consistent throughout the 16 monitoring periods. At only one site was no significant difference found. Streamside areas both inside and outside the weirs were found to have higher rates of sediment deposition than backmarsh areas. At both marsh locations, sediment deposition rates were higher outside the weirs than inside. More sediment was deposited in saline marshes than in brackish or fresh/intermediate areas. The vertical accretion data shows that marshes in most areas are accreting sufficiently rapidly to keep pace with local rates of sea-level rise, except for two areas, both of which are inside weirs.