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261.
BACKGROUND: Animal and epidemiologic data indicate that exposure to persistent organochlorine pollutants (POPs) may disrupt the hypothalamus-pituitary-thyroid (HPT) and the hypothalamus-pituitary-gonadal (HPG) axes. We have assessed whether the POP-biomarkers 2,2'4,4',5,5'-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis(4-chlorophenyl)-ethene (p,p'-DDE) affect thyrotropin (TSH), thyroid hormones, gonadotropins or sex hormone concentrations in men. METHODS: Lipid adjusted serum concentrations of CB-153, and p,p'-DDE, were determined in 196 men (median age 59 years, range 48-82). Hormone analyses in serum were performed with immunoassays. The effect of CB-153 and p,p'-DDE (as continuous or categorized variables) were evaluated by linear regression models, adjusting for potential confounders. RESULTS: There was a significant positive association between p,p'-DDE and TSH. An increase of 100 ng/g lipid of p,p'-DDE corresponded to an increase of 0.03 mU/l (95% Confidence Interval (CI) 0.01, 0.05) in TSH level. The explanatory value (R(2)) of the multivariate model was only 7%. Moreover, there was a significant negative association between p,p'-DDE and estradiol. An increase of 100 ng/g lipid of p,p'-DDE corresponded to a decrease of 0.57 pmol/l (95% CI -1.0, -0.12) in estradiol level. The R(2)-value was only 4%. No associations were observed between any of the POP biomarkers and the other hormones. CONCLUSIONS: The positive association between p,p'-DDE and TSH and the negative association between p,p'-DDE and estradiol, among middle-aged and elderly men, were not accompanied by associations between the POP-markers and thyroxin, testosterone, and gonadotropins, respectively. The results gives some additional support for that POP exposure may affect HPT- and HPG-axes also in humans, but the overall epidemiological data are still not coherent enough to allow any firm conclusions. 相似文献
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At three coastal dune sites at the island of Hiddensee, north-east Germany, vegetation cover was mapped during 2002 and compared
to vegetation surveys from the late 1980s and 1930s. Abiotic and biotic factors, which have been identified as being critical
for coastal dunes in former studies such as disturbance, salt spray or nutrient availability, were measured. Grazing and land-use
history were reviewed by literature and interviews. Tall graminoid communities, mainly Carex arenaria, are a common vegetation unit today. Development, distribution of these dominances and possible causes for its occurrence
have not been analysed. Generally, older successional vegetation units increased and pioneer stages decreased from the 1930s
until 2002. At the geologically youngest site, the southern dunes, grass encroachment by Carex arenaria was highest (ca. 50% cover in 2002), and age and density of trees lower than at the older, central dunes. Land-use changes
such as decrease in grazing pressure, additional feeding of livestock, increase in coastal protection measures and subsequent
decrease in shifting sands as well as varying availability of groundwater and amount of salt spray are relevant factors for
vegetation changes in coastal dunes over the past 70 years. Site-specific land-use differences such as livestock density and
land-use history have a stronger influence than atmospheric N-pollution on the vegetation composition of these acidic, coastal
dunes under low to moderate N-deposition loads of 6–8 kg N ha−1 yr−1. 相似文献
265.
More complex models of forest ecosystems are required to understand how land-cover changes can impact vegetation dynamics and spatial pattern. In order to document spatio-temporal modelling abilities, the observations conducted in the declined climax mountain Norway spruce forest during the recovery period (1995-2006) are used for simulation and spatial analysis in the GIS environment. The developed spatio-temporal model is used for simulation of forest vegetation dynamics in a mountain spruce forest in the framework of regeneration processes after stress from air pollution. In order to explore the spatial and temporal phenomena of regeneration processes, the spatio-temporal model is based on a large set of ordinary differential equations that solve dynamic processes in sets of microsites arranged in grids for each ground vegetation species and each age group of Norway spruce seedlings. The spatial extent of the explored site is composed of a set of 50 × 50 microsites. Each microsite is represented by a square with dimensions of 1 m × 1 m. The presented simulation studies are mainly focused on seedlings from the seed year 1992, in order to explore the longest monitored time series of survival. It is based on exponential growth models that are related to the environmental conditions for each microsite. The canopy gaps based on estimates of the local crown projected area, the soil type layer, and the dominant grass density are used to provide case simulation studies. The first case study simulates the influence of microsite positions in relation to the local tree crown projections on the survival of spruce seedlings. It is assumed that the density of the trees is the main factor that determines the light and heat supply to the ground level of the Norway spruce seedlings. The second case study extends the previous study to include terms that determine the growth ratio in dependence on the crown projection area. The third case study provides further extensions in order to simulate growth ratio relations to the local soil type. The fourth case study demonstrates the local influence of the dominant grasses, such as Avenella flexuosa and Calamagrostis villosa, on the natural regeneration of Norway spruce. Starting from the conditions at the sites before the recovery period, the case simulation studies are able to project the short-term succession for a regeneration decade and the approximate long-term development. In addition to the standard simulation procedures based on solution of ordinary differential equations, spatio-temporal modelling in the GIS environment is able to provide spatial data management, analysis and visualization of the data. 相似文献
266.
Zahradnik E Sander I Kendzia B Fleischer C Brüning T Raulf-Heimsoth M 《Journal of environmental monitoring : JEM》2011,13(9):2638-2644
The aim of this study was to estimate mite antigen exposure in farming environments by passive sampling of airborne dust. Antigen concentrations were measured with enzyme immunoassays specific for three storage mites (SM): Acarus siro, Lepidoglyphus destructor, Tyrophagus putrescentiae and the house dust mite (HDM) Dermatophagoides pteronyssinus. Dust samples were collected with electrostatic dust fall collectors (EDCs) in three different areas of cattle farms. EDCs were placed in cow stables (working area), in changing rooms (transit area) and in different rooms of farmer dwellings (living area). Mite concentrations in the living area of farm homes were compared to those of urban homes. In dust samples from stables, antigens of all four mite species could be detected. The highest exposure level was to L. destructor (median 56.7 μg/m(2)), the lowest to A. siro (median 14.4 μg/m(2)). Mite concentrations of different species showed no correlation within the cow stables. In comparison to stables, the median mite concentrations in farm homes were significantly lower, ranging from below the detection limit to 1.5 μg/m(2). Antigens of SM were predominantly found in changing rooms and kitchens, and HDM antigens were mainly detected in bedrooms. Antigens of all mites were measured the least often in living rooms. T. putrescentiae was the most prevalent mite in all room types, and the exposure levels correlated strongly between different rooms. The number of SM positive samples in farm homes was considerably higher than in urban homes, while the percentage of HDM positive samples did not differ significantly. 相似文献
267.
Constantine N. Antonopoulos Evi Germeni Flora Bacopoulou Vassiliki Kalampoki Stefanos Maltezos Ilias Skalkidis Stella Daskalopoulou Eva Negri Eleni Petridou 《Safety Science》2011,49(6):933-938
Surveillance systems are indispensable for injury prevention; yet, detailed electronic records are rarely available. The “Student’s Health Card” is a self-reporting electronic tool addressing health issues of University students, while aiming to actively involve them in preventive practices and health promotion. Utilizing data from the injury prevention related section, this study sought to investigate the impact of risk-taking behavior on road crash involvement among University students residing in two Mediterranean countries. A total of 978 University students, 451 Greek and 527 Italian, provided information on prior road crash involvement, as well as on eight behavioral variables, comprising a risky behavior score. Multiple logistic regression analysis was performed. The already known tendency for clustering of risky behaviors was evident. One degree increment in the risky behavior score was found to increase the risk of road crash involvement by 35%. Driving after drinking (OR = 2.55, CI = 1.53–4.26), riding with a drunk driver (OR = 2.19, CI = 1.08–4.45) and tobacco smoking (OR = 1.95, CI = 1.18–3.22) significantly multiplied the risk. Despite their better compliance with safety measures, Italian students, compared with Greek, reported worse alcohol-related driving habits and engaged more frequently in mobile phone use while driving. Clustering of risky behaviors was found to be an important predictor of road crash involvement. Screening and awareness of risk-taking propensity of University students could guide early intervention. The “Student’s Health Card” could provide, at minimal cost, reliable risk-taking and road crash involvement information, which is needed for both personal risk assessment and surveillance purposes. 相似文献
268.
Topi K. Lehtonen Bob B. M. Wong P. Andreas Svensson Axel Meyer 《Behavioral ecology and sociobiology》2011,65(4):613-619
In many taxa, parental strategies can vary among individuals. This is especially true in species with biparental care, with
males, more often than females, deserting their mates. While there is an abundance of theoretical predictions and empirical
data on factors inducing mate abandonment by males, much less is known about what consequences this may have on female behaviour,
particularly in the field and in non-avian systems. Here, we compared brood defence rate, behavioural defence types, and brood
success of solitary and paired females in two species of Neotropical cichlid fish in their natural habitat. In terms of the
rate of territorial aggression towards potential brood predators, solitary females were able to fully compensate in the absence
of a male but, in so doing, ended up maintaining smaller territories, which appeared to compromise offspring fitness in at
least one of the two species. Hence, our results suggest that even extensive quantitative compensation in parental effort
by solitary females may not be enough to ensure adequate qualitative compensation for the lack of male participation, highlighting
the importance of distinguishing between these two aspects of compensatory parental care. 相似文献
269.
270.
Dagmar Wieczorek Eva C. Prott Wendy P. Robinson Eberhard Passarge Gabriele Gillessen-Kaesbach 《黑龙江环境通报》2003,23(2):128-133
We report on a live-born male with 46,XY/47,XY+4/47,XY,+6 mosaicism. Trisomy 4 mosaicism was detected by karyotyping chorionic villus samples (CVS) and was confirmed by the analysis of 16 metaphases obtained from cultured amniotic fluid cells. Eight metaphases were normal (46,XY), two had trisomy 4 (47,XY,+4), and two had trisomy 6 (47,XY,+6). Two postnatal chromosomal analyses of blood lymphocytes at birth and at the age of one week were normal. Chromosomal analysis of cultured skin fibroblasts from the right inguinal region at the age of 12 months revealed trisomy 4 (47,XY,+4) in 49 metaphases, trisomy 6 (47,XY,+6) in 2 metaphases, and a normal karyotype (46,XY) in 49 cells of the 100 analyzed metaphases, respectively. The main clinical findings consist of prenatal growth retardation, hypoplasia of the right side of the face, a dysplastic and posteriorly rotated right ear, a high vaulted palate, retrognathia, aplasia of the right thumb, hypoplasia of the fingernails, a deep sacral dimple, and patchy skin hypopigmentation of the right leg. When last seen at the age of 14 months, his development was nearly normal. Five patients with trisomy 4 mosaicism have been reported previously, but none with an additional trisomy 6 mosaicism. Copyright © 2003 John Wiley & Sons, Ltd. 相似文献