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331.
Gametic incompatibility and genetic divergence of Pacific and Kumamoto oysters,Crassostrea gigas and C. sikamea 总被引:1,自引:0,他引:1
The biological and taxonomic separation of the Pacific oyster Crassostrea gigas (Thunberg, 1793) from the Kumamoto oyster C. sikamea (Amemiya, 1928) is affirmed by three concordant lines of evidence: (1) fixed differences in 2% of a mtDNA sequence coding for large subunit rRNA; (2) a genetic distance of 0.440 based on 19 allozyme loci, including 5 diagnostic loci (Aat-1, Idh-1, Idh-2, Mpi-1, Mdh-2); (3) one-way gametic incompatibility resulting in partial reproductive isolation in interspecific crosses. C. gigas sperm x C. sikamea egg fertilizations form viable hybrid offspring, but C. sikamea sperm do not fertilize C. gigas eggs. Divergence between these two species is mediated by differing peaks in the periods for gamete release and by one-way sperm/egg incompatibility. Two attempts to recover C. sikamea from its place of origin in southern Japan have yielded only individuals with the mitochondrial haplotype that characterizes C. gigas. We thus identify a crucial need for careful screening, management, and conservation of the cultivated populations of C. sikamea on the US west coast. 相似文献
332.
Rapid Loss of Genetic Variation in Large Captive Populations of Drosophila Flies: Implications for the Genetic Management of Captive Populations 总被引:2,自引:0,他引:2
D.A. Briscoe J.M. Malpica A. Robertson Gabrielle J. Smith R. Frankham R.G. Banks J.S.F. Barker 《Conservation biology》1992,6(3):416-425
Levels of variation in eight large captive populations of D. melanogaster (census sizes ∼ 5000) that had been in captivity for periods from 6 months to 23 years (8 to 365 generations) were estimated from allozyme heterozygosities, lethal frequencies, and inversion heterozygosities and phenotypic variances, additive genetic variances ( V A ), and heritabilities ( h 2 ) for sternopleural bristle numbers. Correlations between all measures of variation except lethal frequencies were high and significant. All measures of genetic variation declined with time in captivity, with those for average heterozygosities, V A , and h 2 being significant. The effective population size ( N e ) was estimated to be 185–253 in these populations, only 0.037–0.051 of census size (N). Levels of allozyme heterozygosities declined rapidly in two large captive populations founded from another wild stock, being reduced by 86% and 62% within 2.5 years in spite of being maintained at sizes of approximately 1000 and 3500. Estimates of N e / N for these populations were only 0.016 and 0.004. Two estimates of N e / N for captive populations of D. pseudoobscura from data in the literature were also low at 0.036 and 0.012. Consequently, the rate of loss of genetic variation in captive populations and endangered species may be more rapid than hitherto recognized. Merely maintaining captive populations at large census sizes may not be sufficient to maintain essential genetic variation. 相似文献
333.
Christina Goldfine Ph.D James E. Haddow George J. Knight Glenn E. Palomaki 《黑龙江环境通报》1989,9(10):697-700
In this study we define for the first time the distribution of alpha-fetoprotein levels and acetylcholinesterase ratios in amniotic fluid samples associated with fetal gastroschisis. Elevated alpha-fetoprotein levels and positive acetylcholinesterase measurements are found in virtually all cases, indicating that these combined measurements are highly reliable in detecting this lesion. 相似文献
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336.
This prospective study investigates the relationship between insulin-dependent diabetes and maternal serum levels of alpha-fetoprotein (AFP), unconjugated oestriol (uE3), and human chorionic gonadotropin (hCG). It also examines the potential impact on screening for Down syndrome. The population-based cohort included 20 321 pregnant women in Maine who underwent routine serum screening for Down syndrome in the second trimester. The cohort included 52 women with insulin-dependent diabetes. Maternal serum AFP levels are now routinely adjusted for insulin-dependent diabetes. These adjustments, therefore, were made routinely in the diabetic women, but no equivalent adjustments were made for uE3 and hCG values. The initial false-positive rate (using all three markers) among the women with diabetes was not significantly different from that in the non-diabetic population (7·7 and 5·4 per cent, respectively). Prior to adjustment for insulin-dependent diabetes, the median AFP level in the 52 women was 0·73 multiples of the median (MOM); the median levels of uE3 and hCG were 0·93 and 0·98 MOM, respectively. When the uE3 and hCG levels were adjusted, the initial false-positive rate was unchanged. Median serum levels of uE3 were significantly higher in the 33 women whose onset of diabetes was prior to 19 years of age (0·99 MOM) than in the 19 women whose onset of diabetes was at age 19 or older (0·84 MOM). This is the first population-based study to investigate the relationship between diabetes and serum levels of AFP, uE3, and hCG, and confirms earlier observations from a case—control study that found only slightly lower uE3 and hCG levels. 相似文献
337.
Glenn E. Palomaki B.S. James E. Haddow George J. Knight Nicholas J. Wald Anne Kennard Jacob A. Canick Devereux N. Saller Jr Miriam G. Blitzer Lois H. Dickerman Rachel Fisher Dagmar Hansmann Manfred Hansmann David A. Luthy Anne M. Summers Philip Wyatt 《黑龙江环境通报》1995,15(8):713-723
Nine centres collaborated to examine the feasibility of a screening method for trisomy 18 that was based on assigning individual risk, using a combination of maternal age and measurements of alpha-fetoprotein (AFP), unconjugated oestriol (uE3), and human chorionic gonadotropin (hCG). Second-trimester measurements of these analytes were obtained from 94 trisomy 18 pregnancies. In the 89 pregnancies without an associated open defect, the median levels for AFP, uE3, and hCG were 0.65, 0.43 and 0.36 multiples of the unaffected population median, respectively. The strongest individual predictor of risk for trisomy 18 was uE3, followed by hCG, AFP, and maternal age, in that order. Using a method of individual risk estimation that is based on the three markers and maternal age, 60 per cent of pregnancies associated with trisomy 18 would be detected at a risk cut-off level of 1:100, with a false-positive rate of about 0.2 per cent. One in nine pregnancies identified as being at increased risk for trisomy 18 would be expected to have an affected pregnancy. This risk-based screening method is more efficient than an existing method that is based on fixed analyte cut-off levels. Even though the birth prevalence of trisomy 18 is low, prenatal screening can be justified when performed in conjunction with Down syndrome screening and when a high proportion of women offered amniocentesis have an affected fetus. 相似文献
338.
Glenn L. Wise 《环境质量管理》1995,4(3):21-32
Ciba-Geigy is a specialty chemical and pharmaceutical company that is managing over 100 CERCLA and RCRA remediation sites in 38 states. The potential cost is over $500 million. The sites vary in their scope and technical complexity. For years management was frustrated by their lack of control over the selection of cleanup remedies and associated costs. This article shows how the company changed the method of managing remediation projects in an attempt to gain control over the process and improve overall environmental quality performance. 相似文献
339.
Glenn E. Moglen Richard H. McCuen 《Journal of the American Water Resources Association》1990,26(1):145-156
ABSTRACT: A framework for combining economic factors and the hydrolo of detention basins is provided. The general development of economic production functions for water quality (sediment) and flood control is discussed. Example production functions are generated to compare water quality (sediment control only) and flood control. For the given example, the design of a detention basin for downstream sediment control is economically unwarranted. When compared to on-site detention facilities, regional detention structures appear to be more practical from an economic standpoint for water quality control. Since sediment was the only water quality parameter assessed, it is entirely possible that the design of a detention basin for water quality control would be justified if the effects of all pollutants of concern could be quantified. Policy aspects of detention facilities that relate to the economics of water quality control are also discussed. 相似文献
340.
Sociological edge effects: Spatial distribution of human impact in suburban forest fragments 总被引:4,自引:0,他引:4
Glenn R. Matlack 《Environmental management》1993,17(6):829-835
Suburban forest fragments often experience heavy recreational and waste disposal use, with considerable damage to the vegetation.
To suggest strategies for conservation of the forest flora, spatial distributions of human impact were described in 40 fragmentary
stands in northern New Castle County, Delaware. The distribution of human impact showed a significant bias to the forest edge,
with 95% of localized damage occurring in the first 82 m. Forms of impact related to lawn maintenance fell significantly closer
to the edge than impacts related to recreation and showed the strongest edge orientation. Edge distances of campsites, vandalized
trees, and firewood gathering were negatively correlated with distance to the nearest graded road, indicating the importance
of road access. Several forms of impact were also clustered near footpaths, although distance to paths was independent of
edge distance in all cases. In terms of penetration of the forest and severity of damage, human impact greatly exceeds natural
edge effects reported for this community. These findings suggest that damage may be minimized by limiting road access and
avoiding the creation of small forest fragments. 相似文献