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601.
P.R. Lecavalier I. Chu D. Villeneuve V.E. Valli 《Journal of environmental science and health. Part. B》2013,48(5):951-961
Abstract The objective of the present study was to assess the potential interactive effects of two Great Lakes chemical contaminants, hexachlorobenzene (HCB) and mercury (HgCl2). Groups of 10 female Sprague‐Dawley rats were administered by gavage single doses of HCB (400, 600 mg/kg b.w. in corn oil), HgCl2 (10.0, 12.5 mg/kg b.w. aqueous) or combinations of both followed by observation for clinical signs of toxicity for 14 days. Five animals from treatment groups died before the termination of the study; one animal each in 600 mg HCB, 400 mg HCB + 10 mg HgCl2, and 600 mg HCB + 10 mg HgCl2, and two animals in 600 mg HCB + 12.5 mg HgCl2. The surviving animals were necropsied at the termination of the study, and hematological, clinical chemistry, histopathological and tissue residue analyses were performed. Relative liver weights were increased in both low and high dose groups of HCB but not in animals treated with HgCl2 alone. Co‐administration of HgCl2 did not alter the HCB effects on the liver weight of the animals. Serum cholesterol levels were increased in all the groups receiving HCB but not HgCl2. No interactive effects on other serum parameters were seen in animals administered with both chemicals. Mild to moderate morphological changes occurred in the liver, thyroid, thymus, ovary and bone marrow of rats exposed to HCB or HCB + HgCl2, and in the kidney of HgCl2 or HgCl2 + HCB treated animals. More severe histological changes occurred in the groups receiving both chemicals. The histological effects appeared to be additive. It was concluded that co‐administration with HCB and HgCl2 resulted in additive effects in some of the endpoints measured but no synergism or antagonism was observed. 相似文献
602.
I. Chu D.C. Villeneuve V.E. Valli L. Ritter R.J. Norstrom J.J. Ryan 《Journal of environmental science and health. Part. B》2013,48(8-9):713-731
Abstract Lake Ontario coho salmon were known to contain a mixture of chemical contaminants. A previous study demonstrated that rats fed the Lake Ontario fish‐supplemented diet for 28 days exhibited mild biochemical and histological changes. The purpose of the present study was to determine the effects due to a longer term of exposure and the reversibility of these effects. Growth rate and food consumption were not affected by feeding the animals with Lake Ontario or Pacific fish‐supplemented diets for 13 weeks. No deaths were observed. Decreased spleen weights were observed in groups of males fed 1.45%, 5.8% Lake Ontario and 2.9% Pacific diet. After a 13 week recovery the spleen weights returned to normal. Decreased serum potassium was observed in male rats fed 2.9% Lake Ontario diet, and all levels of Pacific diet for 13 weeks, and was not evident following maintenance on normal diet. Serum glucose was not affected by the 13‐week period of treatment, however; a reduction in this parameter occurred in male rats fed the two highest doses of Lake Ontario diet and all doses of Pacific diet following the 13‐week recovery period. Minor hematological changes occurred only in the male rats fed either Lake Ontario or Pacific diet following a 13 week recovery period and included reduced marrow myeloid cells and myeloid/erythroid ratio. Hepatic microsomal ethoxyresorufin deethylase activity was significantly increased in rats ingesting Lake Ontario diet. Mild histological changes occurred in the liver and thyroid of the treated males, and in the liver and kidney of the treated females. These changes were attributed to the chemical residues and/or the fish diet. Data presented here indicated that the Lake Ontario fish‐supplemented diet can cause mild biochemical, hematological and histological changes but most of these were reversible when exposure was terminated. 相似文献
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604.
This study has demonstrated an interaction between the effect of increased ocean acidity and temperature (40 days exposure)
on a number of key physiological parameters in the ophiuroid brittlestar, Ophiura ophiura. Metabolic upregulation is seen in the low pH treatments when combined with low temperature. However, this is far outweighed
by the response to elevated temperature (+4.5°C). In the high temperature/low pH treatments treatments (where calcite is undersaturated)
there appears to be an energetic trade-off likely in order to maintain net calcification where dissolution of calcium carbonate
may occur. This energy deficit results in a ~30% reduction in the rate of arm regeneration at pH 7.3 which is predicted to
be reached by the year 2300. This understanding of how O. ophiura responds to ocean acidification, taking into account an interactive effect of temperature, suggests that fitness and survival
may indirectly be reduced through slower recovery from arm damage. 相似文献
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608.
Environmental conditions causing stress have a significant effect on the generative organs of Scotch pine. The parameters characterizing pine pollen are subject to significant interannual variations and are closely connected with weather and climatic conditions in the period of pollen formation. Airborne pollutants affect the quality of pine pollen, which is especially apparent in the years favorable for the formation of microspores. The ability of Scotch pine pollen to germinate and form pollen tubes in the regions with different technogenic loads proved to be significantly lower than in tree stands of the background areas. 相似文献
609.
T. B. Kalinnikova I. A. Krasnoperova T. M. Gainutdinov S. V. Sadykova M. Kh. Gainutdinov 《Russian Journal of Ecology》2005,36(2):109-114
The thermal resistance of Daphnia magna Straus is a trait depending on the interaction between individuals. The group effect is expressed in D. magna as both a decrease in thermal resistance and a marked individual differentiation with respect to thermal resistance. Two types of interactions between individual D. magna have been found: (1) the release of an unidentified factor decreasing thermal resistance (without noticeably changing the phenotypic variability of this trait) into the medium and (2) a decrease in the thermal resistance of individuals poorly adapted to heat stress, with the thermal resistance of well-adapted individuals (determined by the dependence of thermal resistance on interactions between individuals) remaining the same or even slightly increasing.Translated from Ekologiya, No. 2, 2005, pp. 126–131.Original Russian Text Copyright © 2005 by Kalinnikova, Krasnoperova, T. Gainutdinov, Sadykova, M. Gainutdinov. 相似文献
610.
Combining a computational fluid dynamics (CFD) model and a multi-zonal model, a study was carried out on radon entry through the complex substructure of a house with a cellar. The uniqueness of the radon entry problem in this type of house was due to the involvement of two radon entry routes to two chambers: the cellar and the living area of the house. Soil gas carrying radon was driven through the two routes by two coupled disturbance pressures in the chambers. The effects of temperature differences were considered as another driving force for the radon entry. Examined in this study were the effects of the geometry of the substructure, air permeability of the soil, air-tightness of the cellar shell, and cellar ventilation on radon entry to both the cellar and the living area. The ground floor covering on top of the soil outside a cellar wall increased radon entry through this wall by about 68%, as radon built up to a very high level under the covering. The effect of cellar ventilation was found as follows: the cellar ventilation created a layer of airflow in the soil under the ground floor; the flow passed over a crack in the ground floor, the entry route to the living area, diluting the radon in the area. Hence, the soil gas entering the living area carried less radon. Cellar ventilation seems more effective in reducing radon entry to the living area in a more permeable soil and leaky cellar shell; a moderate cellar ventilation condition achieved 77% reduction in radon entry to the area. When permeability of these two materials was lower and soil radon content remained the same, the chances of radon entry was also lower; hence, the indoor radon level was lower and no radon control was needed. When such soil contains high radon concentration, other mitigation measures must be sought. 相似文献