Silica-supported antimony(III) chloride as a mild and reusable catalyst for the Paal–Knorr pyrrole synthesis

Heterogeneous catalysts are used for control of environmental pollution. Heterogeneous catalysts are easily separated from the reaction mixture, thus allowing their recovery and re-use. There is a need for catalysts that are efficient under mild conditions. Here, we show that silica-supported antimony(III) chloride (SbCl₃/SiO₂) acts as a highly efficient heterogeneous Lewis acid catalyst for the Paal–Knorr pyrrole synthesis at room temperature. We found that condensation of hexane-2,5-dione with aromatic and aliphatic primary amines in hexane using SbCl₃/SiO₂ with 7.6 wt% SbCl₃ was the best reaction condition. The silica support facilitated the workup of the reaction mixture and provided a reusable catalyst at least for 7 runs without significant loss in activity. Indeed, the yield was 98% for the first run and 84% for the 7th run. We conclude that low catalyst loading, operational simplicity, practicability and applicability to various substrates make this reaction an interesting alternative to previously applied procedures. From the environmental standpoint, this eco-friendly catalyst is stable, highly active, easy to prepare and handle.     

Vitamin B1 as a metal-free organocatalyst for greener Paal–Knorr pyrrole synthesis

This investigation discloses a greener reaction to prepare pyrrole derivatives. Metal-free catalysts are greener alternatives to existing metal catalysts in synthetic organic chemistry. Indeed, transition metals are often costly and toxic. They may be found as traces in health reaction products such as pharmaceuticals. Alternatively small organic molecules termed “organocatalysts” allow the synthesis of valuable products without traces of toxic metals. Here, we show for the first time the use of vitamin B₁ as new organocatalyst for the Paal–Knorr pyrrole synthesis under ambient conditions. Reaction conditions were optimized for the reaction of hexane-2,5-dione with 4-methoxyaniline. Ethanol was the most effective solvent. The conversion was quantitative using vitamin B₁, by comparison with a low yield of 30?% without catalysis. The best conditions were performed in ethanol with 5?mol % of vitamin B₁ during 1?h. This reaction was tested using various aromatic amines. To conclude the use of vitamin B₁ for the Paal–Knorr pyrrole, cyclocondensation has mild reaction conditions, is simple to perform, and gives moderate to excellent yields. It is therefore a promising reaction for the preparation of various pyrrole derivatives.     

Synthesis and antibacterial activity of a Fe3O4–AgCl nanocomposite against Escherichia coli

In this investigation, Fe₃O₄ magnetic nanoparticles (MNPs) were prepared by the alkalinization of an aqueous medium containing ferrous sulfate and ferric chloride. In the next step, a Fe₃O₄–AgCl magnetic nanocomposite was fabricated by the drop-by-drop addition of silver nitrate solution into a NaCl solution containing Fe₃O₄ MNPs. All prepared nanoparticles were characterized by transition electron microscopy (TEM), X-ray diffraction (XRD), and energy-dispersive X-ray spectroscopy (EDS). Both particle types varied in size from 2.5 to 20?nm, with an average size of 7.5?nm for Fe₃O₄ MNPs and 12.5?nm for Fe₃O₄–AgCl nanocomposites. The antibacterial effect of the Fe₃O₄ MNPs and fabricated Fe₃O₄–AgCl nanocomposites against Escherichia coli (ATCC 35218) were investigated by conventional serial agar dilution method using the Müller–Hinton Agar medium. The minimum inhibitory concentration was 4?mg?mL^?1 for Fe₃O₄ MNPs and 2?mg?mL^?1 for the Fe₃O₄–AgCl magnetic nanocomposites. Time-kill course assays showed that the Fe₃O₄–AgCl magnetic nanocomposites successfully killed all inoculated bacterial cells during an exposure time of 60?min. The antibacterial activity of recycled Fe₃O₄–AgCl magnetic nanocomposites over four 60?min cycles of antibacterial treatment was further tested against E. coli by the colony-forming unit (CFU) method. The antibacterial efficiency of the nanocomposites was constant over two cycles of antibacterial testing.     

Bioremediation of toxic metals mercury and cesium using three types of biosorbent: bacterial exopolymer,gall nut,and oak fruit particles

Cesium and mercury are two mono-valent elements which can be found in toxic industrial, medical, and nuclear wastes. Their presence in the environment has deleterious effects on the ecosystem, living organisms including humans. Due to the chemical nature of these metals, bioremediation by conventional methods is more difficult to achieve compared to other metals. In this study, we used three biosorbents (oak powder, gall nut, and bacterial exopolymer) for the bioremediation of Hg and Cs. Bio-polymer was produced in the GMS mineral broth. Synthetic wastes of Hg(NO₃)₂ and isotope Cs-133 as the single-metal solutions were used. The biorefining process was carried out in glass columns, made of Pyrex, with dimensions 20?×?7/2?cm² with a V-shaped bottom. The samples were analyzed using atomic absorption. The experimental results showed that eliminated metal percent by oak powder, gall nut, and bacterial exopolymer were, respectively, of 94.8%, 96%, and 13.8% for Hg and 7.8%, 4.4%, and 69.4% for Cs. The tests revealed that Ca⁺⁺, when used as flocculant, played a key role in both biosorption and bio-precipitation rates. Consequently, it was concluded that the investigated biosorbents could be use as an integrated biosorption system for the refinement of mixed wastes.     

Bioaccumulation of heavy metals in fish species of Iran: a review

Environmental Geochemistry and Health - Accumulation of heavy metals (HMs) in fish tissues is an important factor in monitoring the health and safety of aquatic ecosystems. Furthermore, fish are...     

Seasonal variations of polycyclic aromatic hydrocarbons in coastal sediments of a marine resource hot spot: the case of pars special economic energy zone,Iran

Environmental Geochemistry and Health - Polycyclic aromatic hydrocarbons (PAHs) are an important group of compounds of major environmental concern, which are in the class of persistent organic...     

Turbulent velocity profile in fully-developed open channel flows

The determination of velocity profile in turbulent narrow open channels is a difficult task due to the significant effects of the anisotropic turbulence that involve the Prandtl’s second type of secondary flow occurring in the cross section. With these currents the maximum velocity appears below the free surface that is called dip phenomenon. The well-known logarithmic law describes the velocity distribution in the inner region of the turbulent boundary layer but it is not adapted to define the velocity profile in the outer region of narrow channels. This paper relies on an analysis of the Navier–Stokes equations and yields a new formulation of the vertical velocity profile in the center region of steady, fully developed turbulent flows in open channels. This formulation is able to predict time averaged primary velocity in the outer region of the turbulent boundary layer for both narrow and wide open channels. The proposed law is based on the knowledge of the aspect ratio and involves a parameter C_Ar depending on the position of the maximum velocity (ξ_dip). ξ_dip may be derived, either from measurements or from an empirical equation given in this paper. A wide range of longitudinal velocity profile data for narrow open channels has been used for validating the model. The agreement between the measured and the computed velocities is rather good, despite the simplification used.     

Improving Estimation of Specific Surface Area by Artificial Neural Network Ensembles Using Fractal and Particle Size Distribution Curve Parameters as Predictors

Specific surface area (SSA) is one of the principal soil properties used in modeling soil processes. In this study, artificial neural network (ANN) ensembles were evaluated to predict SSA. Complete soil particle-size distribution was estimated from sand, silt, and clay fractions using the model by Skaggs et al. and then the particle-size distribution curve parameters (PSDCPs) and fractal parameters were calculated. The PSDCPs were used to predict 20 particle-size classes for a soil sample’s particle size distribution. Fractal parameters were calculated by the model of Bird et al. In addition, total soil-specific surface area (TSS) was calculated using the above 20 size classes. Pedotransfer functions were developed for SSA and TSS using ANN ensembles from 63 pieces of SSA data taken from the literature. Fractal parameters, PSDCPs, and some other soil properties were used to predict SSA and TSS. Introducing fractal parameters and PSDCPs improved the SSA estimations by 12.5 and 11.1 %, respectively. The improvements were even better for TSS estimations (27.7 and 27.0 %, respectively). The use of fractal parameters as estimators described 44 and 92.8 % of the variation in SSA and TSS, respectively, while PSDCPs explained 42 and 6.6 % of the variation in SSA and TSS, respectively. The results suggested that fractal parameters and PSDCPs could be successfully used as predictors in ANN ensembles to predict SSA and TSS.     

SPME-based air sampling method for inhalation exposure assessment studies: case study on perchlorethylene exposure in dry cleaning

Exposure to perchlorethylene, especially for dry cleaning workers and for people living near dry cleaning shops, could lead to several diseases and disorders. This study examines the value of solid-phase microextraction (SPME) for sampling perchlorethylene in the atmosphere of dry cleaning shops. Carboxen/polydimethylsiloxane (CAR/PDMS) in 0.5-cm retracted mode was selected. There were no significant differences between sampling rates at different temperatures (range of 20 to 30 °C) and air velocities (2 to 50 cm/s). On the opposite, relative humidity (RH) had a significant effect on sampling rates. Method reproducibility was realized in the laboratory and field conditions and was 6.2 % and 7 to 11 %, respectively. Repeatability was also determined as 8.9 %. Comparison of the results according to the American Industrial Hygiene Association exposure assessment strategy showed the SPME sampler yields more conservative results in comparison with traditional standard method.