II. Incidence of Acute Respiratory Illness

A study of acute respiratory illness was conducted from November 1968 through April 1969 among families residing in an area of relatively high nitrogen dioxide exposure, in an area of elevated suspended particulate exposure, and in two control areas of Greater Chattanooga. Respiratory illness rates were consistently higher in all family segments in the high-nitrogen dioxide exposure area when rates were averaged for the entire 24 weeks of study, the A₂/Hong-Kong epidemic period, or post-epidemic interval. A relative excess in respiratory illness of 18.8 percent was found among families exposed to elevated NO₂ concentrations and an excess of 10.4 percent was found among families in the elevated-suspended particulate exposure area.     

Canada's Model Forests 20 years on: towards forest and community sustainability?

We review how Canadian Model Forests pursued forest and community sustainability over the course of two decades (1992–2012). Given its roots in the forest industry and forest science, Model Forest programming initially faced some challenges in pursuing the socio‐economic dimensions of sustainable forest management (SFM) in order to fulfil mandated community sustainability objectives. This was due, in part, to how objectives, stakeholders, and expertise were brought together to develop SFM. The programme helped to define sustainability and the SFM paradigm, advance forest science and social research, and bring together a mix of usually adversarial partners in the name of innovation. Ultimately, the termination of federal programming was linked to high‐level policy shifts, yet difficulty in delivering on the socio‐economic dimensions of SFM during a period of forest sector and community crisis was also a factor.     

Climate change adaptation and mitigation: next steps for cross-sectoral action to protect global health

Effectively addressing the health risks of climate change necessitates an active crosssectoral approach because health risks arise predominantly via sectors such as water, agriculture and energy. Much has been written on climate change and its impact on health, but little attention has focused on the realpolitik of how to progress the development and implementation of health-relevant strategies and policies to reduce this impact. The objective of this paper is to propose three solutions to address current deficiencies: i) strengthening the capacity and understanding of health officials in relation to climate change and health; ii) improving cross-sectoral partnerships with sectors relevant to climate change and health, and iii) identifying organisations influential in the development of climate change mitigation and adaptation strategies and policies, with a view to better target advocacy efforts. Practical examples of each solution are provided. In conclusion, as a steward of public health, the health sector must take the initiative to encourage a cross-sectoral approach that includes capacity development, coupled with an understanding of influential organisations. If this is done effectively, health, social and economic development goals can be reached more efficiently.     

First-trimester prenatal diagnosis of osteogenesis imperfecta type II by DNA analysis and sonography

Osteogenesis imperfecta type II was diagnosed prenatally by analysis of DNA obtained from chorionic villus sampling (CVS) performed at 12 weeks of gestation in a woman who previously had had an affected child. The father had been shown to be mosaic for a mutation in the gene (COL1A2) which encodes the α2(I) chain of type I collagen. An affected fetus was predicted by detection of the mutation in amplified chorionic villus genomic DNA. Ultrasound examination at 13 weeks 4 days demonstrated femoral deformity and virtual absence of calvarial mineralization. In pregnancies at risk for osteogenesis imperfecta type II, sonographic evidence of skeletal abnormalities may be evident by 13 weeks' gestation.     

Freeze/thaw durability of concrete with recycled demolition aggregate compared to virgin aggregate concrete

An increasing trend towards the use of sustainable processes has led to recycled materials being incorporated into concrete. It is generally recognised that crushed recycled construction aggregate material produces concrete of a lower compressive strength, when used as an aggregate replacement due to deleterious materials within the aggregate.It is generally accepted that in the UK, freeze/thaw attack is, after chloride-induced corrosion, the most common cause of concrete deterioration. This paper addresses the freeze/thaw durability of recycled aggregate concrete using a paired comparison test based upon weight loss and final compressive strength.Recycled aggregate concrete was found to be of at least equal durability to concrete manufactured with virgin aggregates. This was due to careful selection of the replacement aggregate and treatment prior to batching.Durability is an important material property and recycled aggregates need to be widely tested to gain confidence for use within the industry and this work shows future possibilities.     

Evaluation of a four year intervention to reduce musculoskeletal hazards among berry growers

PROBLEM: Fresh market berry production workers are exposed to physical risk factors for musculoskeletal injury. METHOD: We disseminated information through trade publications and other sources to berry managers in seven U.S. states about five prevention through design practices that were both safer and more profitable than traditional methods. We administered mail evaluation questionnaires prior to the intervention and after each of four intervention years to rolling, independent U.S. samples and to comparison New Zealand berry farm manager samples after years one through three. RESULTS: U.S. manager self-reports of reading trade publication information increased compared to baseline values for two of five practices and self-reported awareness increased for four of five practices. There were no increases in adoption. More U.S. than New Zealand managers reported getting information about two practices from trade publications and about four practices from public events. No U.S. versus New Zealand differences were observed in reported awareness or adoption for any practice. IMPACT ON INDUSTRY: This study showed that even a modest campaign can build awareness of safer practices fairly quickly in three to four years among small agricultural firms but that increasing adoption apparently requires more time. Widespread adoption of safer practices could help keep operators in business longer as they age by reducing the workload and musculoskeletal strain associated with labor intensive crop production for them and their workforce. Adoption of practices that also improve profits, like the five practices featured in this study, could also help managers stay in business.     

Dietary antioxidants, lipid peroxidation and plumage colouration in nestling blue tits Cyanistes caeruleus

Carotenoid pigments are responsible for many of the red, yellow and orange plumage and integument traits seen in birds. One idea suggests that since carotenoids can act as antioxidants, carotenoid-mediated colouration may reveal an individual's ability to resist oxidative damage. In fact, there is currently very little information on the effects of most dietary-acquired antioxidants on oxidative stress in wild birds. Here, we assessed the impacts on oxidative damage, plasma antioxidants, growth and plumage colouration after supplementing nestling blue tits Cyanistes caeruleus with one of three diets; control, carotenoid treatment or α-tocopherol treatment. Oxidative damage was assessed by HPLC analysis of plasma levels of malondialdehyde (MDA), a by-product of lipid peroxidation. Contrary to predictions, we found no differences in oxidative damage, plumage colouration or growth rate between treatment groups. Although plasma lutein concentrations were significantly raised in carotenoid-fed chicks, α-tocopherol treatment had no effect on concentrations of plasma α-tocopherol compared with controls. Interestingly, we found that faster growing chicks had higher levels of oxidative damage than slower growing birds, independent of treatment, body mass and condition at fledging. Moreover, the chromatic signal of the chest plumage of birds was positively correlated with levels of MDA but not plasma antioxidant concentrations: more colourful nestlings had higher oxidative damage than less colourful individuals. Thus, increased carotenoid-mediated plumage does not reveal resistance to oxidative damage for nestling blue tits, but may indicate costs paid, in terms of oxidative damage. Our results indicate that the trade-offs between competing physiological systems for dietary antioxidants are likely to be complex in rapidly developing birds. Moreover, interpreting the biological relevance of different biomarkers of antioxidant status represents a challenge for evolutionary ecology.     

Characterization of colloidal arsenic at two abandoned gold mine sites in Nova Scotia, Canada, using asymmetric flow-field flow fractionation-inductively coupled plasma mass spectrometry

Asymmetric flow-field flow fractionation-inductively-coupled plasma-mass spectrometry was used to determine whether colloidal arsenic(As) exists in soil pore water and soil extract samples at two arsenic-contaminated abandoned gold mines(Montague and Goldenville, Nova Scotia). Colloidal arsenic was found in 12 out of the 80 collected samples(= 15%), and was primarily associated with iron(Fe) in the encountered colloids. The molar Fe/As ratios indicate that the colloids in some samples appeared to be discrete iron–arsenic minerals, whereas in other samples, they were more consistent with As-rich iron(oxy)hydroxides. Up to three discrete size fractions of colloidal As were encountered in the samples, with mean colloid diameters between 6 and 14 nm. The pore water samples only contained one size fraction of As-bearing colloids(around 6 nm diameter), while larger As-bearing colloids were only encountered in soil extracts.     

Within-year differences in reproductive investment in laboratory zebra finches (<Emphasis Type="Italic">Taeniopygia guttata</Emphasis>), an opportunistically breeding bird

Reproduction in opportunistically breeding bird species has traditionally been considered non-seasonal with individuals taking advantage of favourable environmental conditions as they arise. However, some studies imply that this opportunistic breeding may be superimposed on an underlying seasonality, which has effects on the readiness to breed when conditions are favourable. The zebra finch (Taeniopygia guttata) is the classic opportunistic breeder and widely used as such in studies. In a series of laboratory-based breeding experiments, we found evidence to suggest that there are seasonal differences in maternal reproductive investment in the zebra finch even when photoperiod, temperature, relative humidity and diet were held constant. Females showed highly significant seasonal differences in clutch size and egg mass with laying order. Clutch size showed a spring/summer peak typical of multi-brooded species in the wild. There was also a significant increase in egg mass with laying order in all seasons except winter. This variation in breeding parameters with season may allow females to adjust investment depending on the potential fitness returns from a given reproductive attempt. These findings also raise a warning about interpreting results of multiple zebra finch breeding experiments that have been carried out in different seasons.