Membranpermeation und Antibiotika-Resistenz bei Bakterien

The resistance of mainly gram-negative bacteria against antibiotics is discussed with respect to new discoveries on the permeability barrier of the outer membrane. Proteins originally characterized as virus receptors have been found to be involved in the translocation of certain substrates across the membrane. Antibiotics can reach their target by the same “pores”.     

Papierchromatographische Untersuchung von Thyroxin und anderen Jodthyroninen

The Science of Nature -     

Early amniocentesis at 11–14 weeks' gestation for the diagnosis of fetal chromosomal abnormality—a clinical evaluation

Early arnniocentesis between 11 and 14 weeks' gestation was offered to 110 women at risk of a chromosomally abnormal fetus due to maternal age. Four were found to be unsuitable for the procedure, and 106 early amniocenteses were performed. In 102 cases, clear amniotic fluid was obtained with a single tap. There were two dry taps and two bloodstained tapis; sampling was repeated in three of these cases before 15 weeks. In the fourth case, placental biopsy was performed at 16 weeks. Thus, we were able to obtain a satisfactory sample in all but three cases(2.8 percent). Karyotyping of cells harvested from the early amniotic fluid samples was successful in all the 105 cases. Cell culture from the initial samples revealed a normal karyotype in 99 cases, two balanced translocations, two tetraploid karyotypes, and two cases of pseudomosaicism. Of the 105 pregnancies successfully sampled, there have been two losses to date (1–8 per cent). Two further patients presented with premature rupture of membranes, both pregnancies having successful outcomes. Sixty-two babies have delivered to date, with four congenital anomalies. There were no respiratory problems. Twenty-nine pregnancies are continuing without known complications, and details are not yet available on the remaining 12. The results indicate that early arnniocentesis may replace the traditional test at 15–17 weeks.     

吉林省的风能潜力(英文)

近两年我国电力突然短缺,已经引起政府的高度重视。由于我国风电发展的紧迫性和风电发展的潜力,特别是国际上正在如火如荼地开发风电的情景,中国- 奥地利政府间双边合作计划将风电评估列入2001～2003 年度合作计划,论文是该计划的成果之一。以我国吉林省为研究对象,采用广泛使用的风机选址算法和空间分布诊断程序( WAsP和ZAWIMOD2),运用数字地形图和遥感资料获得的土地利用图,进而得到数字化的表面粗糙度,再对吉林省的风能潜力进行估算。完成了近1km² 分辨率的距地面60m高度的风速和风能密度计算,并制作了它们的分布图。这是我国第一次在较大区域上估算距地面60m 高度的风速和风能密度,其方法对我国风电资源的评估有重要的借鉴作用。结果显示最有效的风能资源在吉林省的中西部地区,而南部和东部的高风资源区位于山脊和山顶,对风能的开发有一定的限制。     

The electromotor system of Torpedo

The electric organ of Torpedo, besides providing abundant amounts of cholinoceptive post-synaptic membrane for the isolation of the acetylcholine receptor protein, is a rich source of cholinergic nerve terminals. Using perfused, innervated tissue blocks from which synaptic vesicles in different functional states can be isolated, much information can be obtained about synaptic-vesicle dynamics. So far this is consistent with the view that the synaptic vesicles are the source of transmitter released on stimulation and that uptake of newly synthesized transmitter by the vesicles is dependent on their having discharged their previous charge of transmitter in at least one cycle of exo- and endocytosis. Studies of the protein composition of the vesicle membrane, especially when combined with similar information about the external presynaptic membrane, purified samples of which are now available from synaptosome (T-sac) preparations, promise to throw new light on the molecular mechanism underlying vesicle exo-/endocytosis.     

NATURAL GAS PROSPECTS IN DEVELOPING COUNTRIES AND THE ROLE OF LNG TRANSPORTATION

Natural gas may provide a major contribution to the world energy supply during the next few decades. The developing countries command about 50 per cent of the world proved natural gas reserves, with gas accounting for only 6 per cent of commercial primary energy production. The challenging task of expanding gas production and utilization in the developing countries, especially through effective use of gas associated with petroleum deposits and transportation of gas in liquefied form (LNG), will require long-term technical co-operation policy commitments with regard to investment, manpower and the transfer of technology. The article is intended to analyse the basic factors involved in these problems. Au cours des prochaines décennies, le gaz naturel peut constituer un apport considérable à l'approvisionnement énergétique mondial. Les pays en développement détiennent approximativement 50 pour cent des réserves mondiales prouvées de gaz naturel, le gaz représentant seulement 6 pour cent de la production d'énergie primaire commerciale. Le défi lancé par la production et l'utilisation croissantes de gaz dans les pays en développement, particulièrement par l'utilisation efficace du gaz lié aux gisements de pétrole et le transport du gaz liquéfié (GNL), requiert des engagements à long terme en matière de politique de coopération technique dans le domaine des investissements, de la main-d'oeuvre et du transfert de technologie. Cet article a pour but d'analyser les facteurs fondamentaux à prendre en considération lorsqu'on traite de ces problèmes. El gas natural podría representar una gran contribucíon a la oferta mundial de energía dentro de las próximas décadas. Los países en desarrollo poseen cerca del 50 porciento de la reserva provada mundial de gas y solamente el 6 porciento de la producción primaria de energía comercial proviene del gas. La tarea de expandir la producción y utilización de gas en los países en desarrollo, especialmente ia utilización efectiva en forma líquida (LNG) de gas asociado al petróleo, requiere de compromisos de cooperación técnica a largo plazo en lo referente a inversiones, recursos humanos y transferencia de tecnología. Este artículo intenta analizar los factores básicos pertinentes a dicha tarea.