Soils can be contaminated by pharmaceuticals. The aim of this study was to evaluate the impact of soil conditions (influencing sorption and persistence of pharmaceuticals in soils) and plant type on the root uptake of selected pharmaceuticals and their transformation in plant-soil systems. Four plants (lamb’s lettuce, spinach, arugula, radish) planted in 3 soils were irrigated for 20 days (26) with water contaminated by one of 3 pharmaceuticals (carbamazepine, atenolol, sulfamethoxazole) or their mixture. The concentrations of pharmaceuticals and their metabolites in soils and plant tissues were evaluated after the harvest. Sulfamethoxazole and atenolol dissipated rapidly from soils. The larger concentrations of both compounds and an atenolol metabolite were found in roots than in leaves. Sulfamethoxazole metabolites were below the limits of quantifications. Carbamazepine was stable in soils, easily uptaken, accumulated, and metabolized in plant leaves. The efficiency of radish and arugula (both family Brassicaceae) in metabolizing was very low contrary to the high and moderate efficiencies of lamb’s lettuce and spinach, respectively. Compounds’ transformations mostly masked the soil impact on their accumulation in plant tissues. The negative relationships were found between the carbamazepine sorption coefficients and its concentrations in roots of radish, lamb’s lettuce, and spinach.
Objective: The present article identifies and assesses the effect of critical factors on the risk of motorcycle loss-of-control (LOC) crashes.
Method: Data come from a French project on road crashes, which include all fatal road crashes and a random sample of 1/20th of nonfatal crashes in France in 2011, based on police reports. A case–control study was carried out on a sample of 903 crashes for 444 LOC motorcycle riders (case) and 470 non-LOC and nonresponsible motorcycle riders (control). The sample was weighted due to the randomization of nonfatal crashes. Missing values were imputed using multiple imputation.
Results: Road alignment and surface conditions, human factors, and motorcycle type played important roles in motorcycle LOC crashes. Riding in a curve was associated with a 3-fold greater risk of losing control of motorcycle than riding in a straight line. Poor road adhesion significantly increased the risk of losing control; the risk increased more than 20-fold when deteriorated road adhesion was encountered unexpectedly, due to loose gravel, ice, oil, bumps, road marking, metal plates, etc. For motorcyclists, riding with a positive blood alcohol concentration (over or equal to the legal limit of 0.5 g/L) was very dangerous, often resulting in losing control. The risk of LOC crash varied for different types of motorcycle: Riders of roadsters and sports bikes were more likely to have an LOC crash greater than that of riders of basic or touring motorcycles. In addition, LOC risk increased with speed; a model using the square of the traveling speed showed better fit than one using speed itself.
Conclusion: The LOC crash factors related to riders, vehicles, and road infrastructure identified here were expected but were rarely identified and taken simultaneously into account in previous studies. They could be targeted by countermeasures to improve motorcyclist safety. 相似文献
Regional Environmental Change - Historical land use may shape landscapes for centuries into the future, but it remains unclear how much land-use legacies affect contemporary land use. Knowing for... 相似文献
The objective of this paper is to characterize the spatiotemporal variations of vegetation phenology along latitudinal and altitudinal gradients in Greenland, and to examine local and regional climatic drivers. Time-series from the Moderate Resolution Imaging Spectroradiometer (MODIS) were analyzed to obtain various phenological metrics for the period 2001–2015. MODIS-derived land surface temperatures were corrected for the sampling biases caused by cloud cover. Results indicate significant differences between West and East Greenland, in terms of both observed phenology during the study period, as well as the climatic response. The date of the start of season (SOS) was significantly earlier (24 days), length of season longer (25 days), and time-integrated NDVI higher in West Greenland. The sea ice concentration during May was found to have a significant effect on the date of the SOS only in West Greenland, with the strongest linkage detected in mid-western parts of Greenland. 相似文献
Substantial percentage of world food production depends on pollinating service of honeybees that directly depends on their health status. Among other factors, the success of bee colonies depends on health of developed larvae. The crucial phase of larval development is the first 6 days after hatching when a worker larva grows exponentially and larvae are potentially exposed to xenobiotics via diet. In the present study, we determined the lethal concentration LC50 (72 h) following single dietary exposure of honeybee larvae to formetanate under laboratory conditions, being also the first report available in scientific literature. Activities of antioxidant enzymes, superoxide dismutase (SOD), catalase (CAT) and glutathione-S-transferase (GST) were also measured in the homogenates of in vitro reared honeybee larvae after single formetanate exposure. Decreased specific activity of SOD and increased activities of CAT and GST suggest the induction of oxidative stress. Higher levels of thiobarbituric reactive species in all samples supported this fact. Comparing determined larval toxicity (LC50 of 206.01 mg a.i./kg diet) with adult toxicity data, we can suppose that the larvae may be less sensitive to formetanate than the adult bees. 相似文献
Environmental Economics and Policy Studies - We have collected data from a world-wide survey among COP delegates to empirically investigate preferences for certain burden sharing rules among key... 相似文献
Mink (Mustela vison) carcasses were collected from local commercial trappers from fall 1998 to spring 2003 from tributaries and marshes within 4.8km from the shores of Lakes Erie and St. Clair, including the Wheatley Harbour and St. Clair River Areas of Concern (AOCs), as well as from inland sites (8 to 40km from shore). Liver concentrations, on a lipid weight basis, of chlorinated hydrocarbons were measured and compared among sites and to tissue concentrations of mink from two previous collections from similar sites over the past 25 years. Mink from the western Lake Erie sites, which included the Wheatley Harbour AOC, had significantly higher concentrations of sum PCBs and PCB Aroclors than those from the St. Clair corridor or inland sites, with concentrations from the rest of Lake Erie being intermediate. Dieldrin concentrations were also significantly higher in western Lake Erie than many other sites, and those of oxychlordane and mirex also tended to be higher (0.05 < p < 0.1). There were no differences in contaminant concentrations between the St. Clair River AOC and the downstream non-AOC Lake St. Clair site, with the exception of slightly higher levels of octachlorostyrene (OCS). Concentrations of PCBs and other chlorinated hydrocarbons in mink showed a general decrease over the past two decades. In contrast, PCBs and some organochlorine pesticides tended to increase, significantly so with oxychlordane, in western Lake Erie mink over the same time period. DDE declined at all sites. Currently, mink liver PCB concentrations are within the range associated with reproductive impairment, as determined from captive mink studies, in 11.7% of all animals collected from the Lakes Erie and St. Clair basin overall, but in almost 40% of individuals from western Lake Erie. 相似文献