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621.
Noninvasive prenatal testing (NIPT) using cell-free DNA (cfDNA) from maternal serum has been clinically available since 2011. This technology has revolutionized our ability to screen for the common aneuploidies trisomy 21 (Down syndrome), trisomy 18, and trisomy 13. More recently, clinical laboratories have offered screening for other chromosome abnormalities including sex chromosome abnormalities and copy number variants (CNV) without little published data on the sensitivity, specificity, and positive predictive value. In this debate, the pros and cons of performing prenatal screening via cfDNA for all chromosome abnormalities is discussed. At the time of the debate in 2017, the general consensus was that the literature does not yet support using this technology to screen for all chromosome abnormalities and that education is key for both providers and the patients so that the decision-making process is as informed as possible. 相似文献
622.
The current study examines the empowering effects of transformational leaders and the extent to which these effects differ across mechanistic–organic organizational contexts. Psychological empowerment is hypothesized to provide a comprehensive motivational mechanism explaining the relationships between transformational leadership and employee job‐related behaviors. In addition, the relationships between transformational leadership, employee psychological empowerment, and job‐related behaviors are hypothesized to be stronger in organizations with more organic as opposed to mechanistic structures. Results based on a cross‐organizational sample of employees and their immediate supervisors provide support for the hypothesized relationships. Psychological empowerment mediated relationships between transformational leadership and employee task performance and organizational citizenship behaviors. The mediating role of psychological empowerment was then found to be conditional upon mechanistic–organic contexts. More specifically, organic structures enhanced, whereas mechanistic structures constrained, the empowering influence of transformational leaders. In highly mechanistic contexts, the indirect effects were no longer statistically significant. Implications for theory, research, and organizational management are discussed. Copyright © 2013 John Wiley & Sons, Ltd. 相似文献
623.
Mary Engels Liann Correia Sarah Piwinski Lanna Cheng Erik Zettler 《Marine Biology》2014,161(6):1241-1250
Five species of the marine insect Halobates share similar ecology but have distinct biogeographic ranges in the eastern tropical Pacific, a region from approximately 75°W–160°W and 10°S–35°N. Between 2001 and 2010, the Sea Education Association collected Halobates from 682 neuston tows (surface net 1 m × 0.5 m, 335-μm mesh) during fifteen cruises between San Diego, USA, Mexico and Tahiti. Total Halobates spp. densities varied substantially from year to year, but our data do not show a sustained change from a data set collected 40 years earlier from 1967 to 1968 (Cheng and Shulenberger in Fish Bull 78(3):579–591, 1980). Halobates are sensitive to sea surface temperature and we observed significant differences in species distributions over time, but these were not due to differences in water temperature or climate change. Our analyses show that the patterns observed are attributable to substantial but previously undescribed seasonal shifts that occur each year in the ranges for both Halobates sobrinus and Halobates micans. There is substantial overlap in ranges during seasonal shifts, but very little co-occurrence of H. sobrinus and H. micans in individual net tows, suggesting biological mechanisms rather than physical factors are restricting distribution and co-occurrence of these two species. 相似文献
624.
Amanda Marsh Linda K. Blum Robert R. Christian Elijah RamseyIII Amina Rangoonwala 《Journal of Coastal Conservation》2016,20(4):335-350
We measured an array of biophysical and spectral variables to evaluate the response and recovery of Spartina alterniflora to a sudden dieback event in spring and summer 2004 within a low marsh in coastal Virginia, USA. S. alterniflora is a foundation species, whose loss decreases ecosystem services and potentiates ecosystem state change. Long-term records of the potential environmental drivers of dieback such as precipitation and tidal inundation did not evidence any particular anomalies, although Hurricane Isabel in fall 2003 may have been related to dieback. Transects were established across the interface between the dieback area and apparently healthy areas of marsh. Plant condition was classified based on ground cover within transects as dieback, intermediate and healthy. Numerous characteristics of S. alterniflora culms within each condition class were assessed including biomass, morphology and spectral attributes associated with photosynthetic pigments. Plants demonstrated evidence of stress in 2004 and 2005 beyond areas of obvious dieback and resilience at a multi-year scale. Resilience of the plants was evident in recovery of ground cover and biomass largely within 3 y, although a small remnant of dieback persisted for 8 y. Culms surviving within the dieback and areas of intermediate impact had modified morphological traits and spectral response that reflected stress. These morphometric and spectral differences among plant cover condition classes serve as guidelines for monitoring of dieback initiation, effects and subsequent recovery. Although a number of environmental and biotic parameters were assessed relative to causation, the reason for this particular dieback remains largely unknown, however. 相似文献
625.
Mary?E.?ShotwellEmail author Wayne?E.?McFee Elizabeth?H.?Slate 《Environmental and Ecological Statistics》2016,23(4):585-603
Much of what is known about bottle nose dolphin (Tursiops truncatus) anatomy and physiology is based on necropsies from stranding events. Measurements of total body length, total body mass, and age are used to estimate growth. It is more feasible to retrieve and transport smaller animals for total body mass measurement than larger animals, introducing a systematic bias in sampling. Adverse weather events, volunteer availability, and other unforeseen circumstances also contribute to incomplete measurement. We have developed a Bayesian mixture model to describe growth in detected stranded animals using data from both those that are fully measured and those not fully measured. Our approach uses a shared random effect to link the missingness mechanism (i.e. full/partial measurement) to distinct growth curves in the fully and partially measured populations, thereby enabling drawing of strength for estimation. We use simulation to compare our model to complete case analysis and two common multiple imputation methods according to model mean square error. Results indicate that our mixture model provides better fit both when the two populations are present and when they are not. The feasibility and utility of our new method is demonstrated by application to South Carolina strandings data. 相似文献
626.
J. Brian Houston Megan K. Schraedley Mary E. Worley Katherine Reed Janet Saidi 《Disasters》2019,43(3):591-611
Natural and human‐caused disasters pose a significant risk to the health and well‐being of people. Journalists and news organisations can fulfil multiple roles related to disasters, ranging from providing warnings, assessing disaster mitigation and preparedness, and reporting on what occurs, to aiding long‐term recovery and fostering disaster resilience. This paper considers these possible functions of disaster journalism and draws on semi‐structured interviews with 24 journalists in the United States to understand better their approach to the discipline. A thematic analysis was employed, which resulted in the identification of five main themes and accompanying subthemes: (i) examining disaster mitigation and preparedness; (ii) facilitating recovery; (iii) self‐care and care of journalists; (iv) continued spread of social media; and (v) disaster journalism ethics. The paper concludes that disaster journalism done poorly can result in harm, but done well, it can be an essential instrument with respect to public disaster planning, management, response, and recovery. 相似文献
627.
This paper presents results of a social cost–benefit analysis (CBA) of afforestation and soil moisture treatment of common lands under an integrated watershed development programme in Karnataka State, India. The aim of the study was to find out if soil moisture conservation and afforestation measures were justified in terms of economic efficiency. The assessment was undertaken by calculating the economic internal rate of return (EIRR) for five village common lands in two watersheds, Uparhalla and Chinnahagari, in central Karnataka. Focused group discussions were organised, using a semi-structured questionnaire and various stakeholders, including project implementing agencies, self help groups and other community-based organisations. The attractiveness of the programme in both watersheds for landless and land owners was high in three out of five sampled villages, with an EIRR ranging from 19% to 91%, while two villages in Chinnahagari watershed had extremely low EIRR, reflecting poor management of soil moisture and afforestation interventions and lack of institutional cohesion to sustain investments made to develop common lands. Therefore, the CBA conducted in the KAWAD project, except for two villages, shows that the investment made to develop common lands should yield substantial economic returns in the long term under a business as usual scenario. 相似文献
628.
Edward R. Carr Philip M. Wingard Sara C. Yorty Mary C. Thompson Natalie K. Jensen Justin Roberson 《国际发展与全球生态学杂志》2013,20(6):543-555
The DPSIR framework was devised in the late 1990s as a tool for the reporting and analysis of environmental problems, ranging in scale from global systems to localized watersheds. Since then, international organizations have begun to apply this framework to the evaluation of sustainable development initiatives, to better understand and overcome barriers to sustainability. While this may seem a logical application for an integrated environmental assessment tool, the use of DPSIR in sustainable development will likely perpetuate the least satisfactory outcomes of development. DPSIR cannot address the impact of aggregated, informal responses on the drivers and pressures related to environmental problems and sustainability challenges. This problem is not merely an oversight of the framework, but an issue that emerges within the structure of DPSIR itself through the unexamined, unacknowledged hierarchy of actors that this framework implicitly creates with its typology. Therefore, a DPSIR-centered approach is not a new direction for development within international organizations, but instead, a reproduction of existing inequalities between actors and stakeholders within current approaches. 相似文献
629.
Invasive plants may have variable effects within a given environment depending on their interactions with the dominant native species, yet little research has examined such species-species interactions within a site. Savanna trees with nonoverlapping canopies offer an ideal opportunity to assess associated changes in the ecosystem processes that result from interactions between an invasive species and different native tree species. We examined the influence of the exotic invasive shrub Lonicera maackii on decomposition dynamics under three native tree species: Fraxinus quadrangulata, Quercus muehlenbergii, and Carya ovata. Litter decomposition rates and litter C and N were evaluated over two years using single- and mixed-species litterbags (L. maackii and individual tree species litter); microarthropod abundance was measured at 6 weeks using Tulgren funnels. Litter from the invasive L. maackii decomposed and lost N more rapidly than the litter of the three native tree species. The rate at which L. maackii decomposed depended on its location, with L. maackii litter decomposing and losing N more rapidly under C. ovata than under the other two native tree species. Mixing L. maackii with the native species' litter did not accelerate litter mass loss overall but did result in synergistic N losses at variable times throughout the experiment, further highlighting the variable interaction between native species and L. maackii. Nitrogen loss was significantly higher than expected in mixtures of C. ovata + L. maackii litter at 6 weeks, in F. quadrangulata + L. maackii litter at 12 weeks, and in Q. muehlenbergii + L. maackii litter at 24 weeks. If the effects of invasive species on certain ecosystem processes, such as litter decomposition, are strongly influenced by their association with native species, this could suggest the need for a more nuanced understanding of the vulnerability of ecosystem processes to invasions of L. maackii and potentially other invasive species. 相似文献
630.
Pius Lee Youhua Tang Daiwen Kang Jeff McQueen Marina Tsidulko Ho-Chun Huang Sarah Lu Mary Hart Hsin-Mu Lin Shaocai Yu Geoff DiMego Ivanka Stajner Paula Davidson 《Environmental Fluid Mechanics》2009,9(1):23-42
Discrepancies in grid structure, dynamics and physics packages in the offline coupled NWS/NCEP NAM meteorological model with
the U.S. Environmental Protection Agency Community Multiscale Air Quality (CMAQ) model can give rise to inconsistencies. This
study investigates the use of three vertical mixing schemes to drive chemistry tracers in the National Air Quality Forecast
Capability (NAQFC). The three schemes evaluated in this study represent various degrees of coupling to improve the commonality
in turbulence parameterization between the meteorological and chemistry models. The methods tested include: (1) using NAM
predicted TKE-based planetary boundary height, h, as the prime parameter to derive CMAQ vertical diffusivity; (2) using the NAM mixed layer depth to determine h and then proceeding as in (1); and (3) using NAM predicted vertical diffusivity directly to parameterize turbulence mixing
within CMAQ. A two week period with elevated surface O3 concentrations during the summer 2006 has been selected to test these schemes in a sensitivity study. The study results are
verified and evaluated using the EPA AIRNow monitoring network and other ozonesonde data. The third method is preferred a
priori as it represents the tightest coupling option studied in this work for turbulent mixing processes between the meteorological
and air quality models. It was found to accurately reproduce the upper bounds of turbulent mixing and provide the best agreement
between predicted h and ozonesonde observed relative humidity profile inferred h for sites investigated in this study. However, this did not translate into the best agreement in surface O3 concentrations. Overall verification results during the test period of two weeks in August 2006, did not show superiority
of this method over the other 2 methods in all regions of the continental U.S. Further efforts in model improvement for the
parameterizations of turbulent mixing and other surface O3 forecast related processes are warranted. 相似文献