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931.
In this Concepts & Synthesis paper, we expand the definition of chronodisruption in humans by proposing that it can be operationalized as the split nexus of internal and external times. With this premise, we suggest how chronotype may be used as a temporal marker (chronomarker) of exposure to chronodisruption in studies of cancer, and beyond, offer cancer risk predictions for observational research on the basis of a chronotype-related hypothesis and corollary, and point to first empirical data in humans. In an a priori way, we examine possible outcomes and perspectives for preventive measures following from our rationale and the suggested chronobiology-driven studies and close with overall advances of chronodisruption research. 相似文献
932.
Christopher D. Pull William O. H. Hughes Mark J. F. Brown 《Die Naturwissenschaften》2013,100(12):1125-1136
Pathogens exert a strong selection pressure on organisms to evolve effective immune defences. In addition to individual immunity, social organisms can act cooperatively to produce collective defences. In many ant species, queens have the option to found a colony alone or in groups with other, often unrelated, conspecifics. These associations are transient, usually lasting only as long as each queen benefits from the presence of others. In fact, once the first workers emerge, queens fight to the death for dominance. One potential advantage of co-founding may be that queens benefit from collective disease defences, such as mutual grooming, that act against common soil pathogens. We test this hypothesis by exposing single and co-founding queens to a fungal parasite, in order to assess whether queens in co-founding associations have improved survival. Surprisingly, co-foundresses exposed to the entomopathogenic fungus Metarhizium did not engage in cooperative disease defences, and consequently, we find no direct benefit of multiple queens on survival. However, an indirect benefit was observed, with parasite-exposed queens producing more brood when they co-founded, than when they were alone. We suggest this is due to a trade-off between reproduction and immunity. Additionally, we report an extraordinary ability of the queens to tolerate an infection for long periods after parasite exposure. Our study suggests that there are no social immunity benefits for co-founding ant queens, but that in parasite-rich environments, the presence of additional queens may nevertheless improve the chances of colony founding success. 相似文献
933.
Michael Armin Borowitzka Navid Reza Moheimani 《Mitigation and Adaptation Strategies for Global Change》2013,18(1):13-25
There is currently great interest in microalgae as sources of renewable energy and biofuels. Many algae species have a high lipid content and can be grown on non-arable land using alternate water sources such as seawater. This paper discusses in detail the issue of sustainability of commercial-scale microalgae production of biofuels with particular focus on land, water, nutrients (N and P) and CO2 requirements and highlights some of the key issues in the very large scale culture of microalgae which is required for biofuels. The use of genetically modified algae is also considered. 相似文献
934.
Michael Gebhardt Markus Ess Sascha Weikert Wolfgang Knapp Konrad Wegener 《Journal of Manufacturing Processes》2013,15(4):452-459
Thermal errors of machine tools are one of the major sources of inaccuracy. Therefore, the reduction of temperature induced deviations or the compensation of the resulting tool center point (TCP) errors have been of strong interest to the manufacturing industry for a couple of years. Up to now, the observation of the environment, the main spindle, the linear axes and the machine bed were in the focus of research, but with the rising demand for 5-axis machine tools and the increasing requirements regarding their accuracy, the analysis of the thermal behavior of rotary axes becomes more and more important. This paper gives an overview of corresponding thermal measurements of machine tools. The thermal behavior of rotary and swiveling axes is analyzed in detail. A simulation model and an approach for a phenomenological compensation of the TCP error are introduced and verified by measurements. 相似文献
935.
936.
M. M. P. B. Fuentes M. R. Fish J. A. Maynard 《Mitigation and Adaptation Strategies for Global Change》2012,17(1):51-63
Climate change poses a serious threat to sea turtles (Cheloniidae) as their terrestrial reproductive phase is only successful
within a limited range of environmental and physical conditions. These conditions are likely to become less optimal as climate
change progresses. To date, management and conservation of sea turtles has focused almost entirely on non-climatic stressors,
due at least in part to practitioners not knowing what strategies to take and the feasibility and risks of potential strategies.
To aid the management of sea turtles in a changing environment, we identified management strategies via a focus workshop and
surveys to mitigate the impacts of climate change to the terrestrial reproductive phase of sea turtles. The effectiveness,
ecological risks and potential social and logistical constraints associated with implementing each of the identified management
strategies is discussed. Twenty management strategies were identified; strategies varied from habitat protection to more active
and direct manipulation of nests and the nesting environment. Based on our results, we suggest a three-pronged approach to
sea turtle conservation in light of climate change, where managers and researchers should: 1) enhance sea turtle resilience
to climate change by mitigating other threats; 2) prioritise implementing the ‘no regret’ and ‘reversible’ management strategies
identified here; and 3) fill the knowledge gaps identified to aid the trial and implementation of the potential strategies identified here. By combining these three approaches our collective toolkit of sea turtle management strategies
will expand, giving us an array of viable approaches to implement as climate change impacts become more extreme. 相似文献
937.
Ellen M. Douglas Paul H. Kirshen Michael Paolisso Chris Watson Jack Wiggin Ashley Enrici Matthias Ruth 《Mitigation and Adaptation Strategies for Global Change》2012,17(5):537-562
We explored the possible future impacts of increased coastal flooding due to sea level rise and the potential adaptation responses
of two urban, environmental justice communities in the metropolitan Boston area of Massachusetts. East Boston is predominantly
a residential area with some industrial and commercial activities, particularly along the coastal fringe. Everett, a city
to the north of Boston, has a diversified industrial and commercial base. While these two communities have similar socioeconomic
characteristics, they differ substantially in the extent to which residents would be impacted by increased coastal flooding.
In East Boston, a large portion of residents would be flooded, while in Everett, it is the commercial/industrial districts
that are primarily vulnerable. Through a series of workshops with residents in each community, we found that the target populations
do not have an adaptation perspective or knowledge of any resources that could assist them in this challenge. Furthermore,
they do not feel included in the planning processes within their communities. However, a common incentive for both communities
was an intense commitment to their communities and an eagerness to learn more and become actively engaged in decisions regarding
climate change adaptation. The lessons that can be applied to other studies include 1) images are powerful tools in communicating
concepts, 2) understanding existing cultural knowledge and values in adaptation planning is essential to the planning process
and 3) engaging local residents at the beginning of the process can create important educational opportunities and develop
trust and consensus that is necessary for moving from concept to implementation. 相似文献
938.
Dimensional analysis and scaling in mechanical mixing for fabrication of metal matrix nanocomposites
S. García-Rodríguez N. Alba-Baena N.M. Rudolph J. Wellekoetter X.C. Li T.A. Osswald 《Journal of Manufacturing Processes》2012,14(3):388-392
For a successful enhancement of mechanical properties of metal matrix nanocomposites, a homogeneous nanoparticle dispersion and distribution in the solidified metal is required. Mechanical mixing can be used for initial break-up of agglomerates, and its study can be simplified with dimensional analysis. Using this technique, mixing time and vortex height were assessed while varying fluid properties, impeller angle, and angular speed. Three relevant dimensionless numbers were recognized: the Reynolds (Re), Froude and Galilei (Ga) numbers. Based on blade and impeller shaft angles, a modified Froude number (Fr*) was defined. These parameters were calculated experimentally, varying angular speed from 200 to 1000 rpm for three different impeller angles: 0°, 15° and 30°. This procedure was performed with three fluids: water, and two aqueous glycerin solutions (25% and 50% by volume). Digital images were taken and processed to measure vortex height. Mixing time was measured for water at 0° impeller angle, angular speed ranging from 200 to 1200 rpm. Results showed an optimal dimensionless mixing time with respect to Re. A linear relationship was found between dimensionless vortex height and Fr*. The first had a second order polynomial relationship with the product ReFr*, regardless of impeller angle. This relationship, together with the Ga, specific for each fluid, allows scaling the results to other fluids such as molten pure aluminum. This study allows experimenting in simpler systems that involve transparent fluids, room temperature and low cost, to then elaborate a prediction of vortex height in fluids where measurements are difficult and costly, such as molten metals. 相似文献
939.
Building regional priorities in forests for development and adaptation to climate change in the Congo Basin 总被引:1,自引:0,他引:1
Denis J. Sonwa Johnson N. Nkem Monica E. Idinoba Mekou Y. Bele Cyprain Jum 《Mitigation and Adaptation Strategies for Global Change》2012,17(4):441-450
Indentifying common priorities in shared natural resource systems constitutes an important platform for implementing adaptation
and a major step in sharing a common responsibility in addressing climate change. Predominated by discourses on REDD + (Reduced
Emissions from Deforestation and Forest Degradation and conservation, sustainable management of forests and enhancement of
forest carbon stocks in developing countries) with little emphasis on adaptation there is a risk of lack of policy measures
in addressing climate change in the Congo Basin. Forest products and ecosystem services provide security portfolios for the
predominantly rural communities, and play major roles in national development programmes in both revenue and employment opportunities.
Thus, raising the profile of forests in the policy arena especially in the twin roles of addressing climate change in mitigation
and adaptation and achieving resilient development is crucial. Within the framework of the Congo Basin Forests and Climate
Change Adaptation project (COFCCA) project, science policy dialogue was conducted to identify and prioritize forest based
sectors vulnerable to climate change but important to household livelihoods and national development. The goal of the prioritization
process was for the development of intervention in forest as measures for climate change adaptation in Central Africa. Participants
constituted a wide range of stakeholders (government, Non Governmental Organizations, research institutions, universities,
community leaders, private sectors etc.) as representatives from three countries directly involved in the project: Cameroon,
Central African Republic and Democratic Republic of Congo. Building on national priorities, four forest related sectors were
identified as common priorities at the regional level for focus on climate change adaptation. These sectors included: (1)
energy with emphasis on fuel wood and Charcoal; (2) Water principally quality, quantity, accessibility, etc.; (3) Food with emphasis on Non Timber Forest Products, and (4) Health linked to healthcare products (medicinal plants). Using these prioritized sectors, the project focused on addressing the impacts of climate change on local communities and the development of adaptation strategies in the three pilot countries
of the Congo Basin region. The four sectors constitute the key for development in the region and equally considered as priority sectors in the poverty
reduction papers. Focused research on these sectors can help to inject the role of forests in national and local development
and their potentials contributions to climate change adaptation in national and public discourses. Mainstreaming forest for
climate change adaptation into national development planning is the key to improve policy coherence and effectiveness in forest
management in the region. 相似文献
940.
Simon?BrinerEmail author Michael?Hartmann Robert?Finger Bernard?Lehmann 《Mitigation and Adaptation Strategies for Global Change》2012,17(4):337-355
We assessed the economic suitability of 4 greenhouse gas (GHG) mitigation options and one GHG offset option for an improvement
of the GHG balance of a representative Swiss suckler cow farm housing 35 Livestock units and cultivating 25 ha grassland.
GHG emissions per kilogram meat in the economic optimum differ between the production systems and range from 18 to 21.9 kg
CO2-eq./kg meat. Only GHG offset by agroforestry systems showed the potential to significantly reduce these emissions. Depending
on the production system agroforestry systems could reduce net GHG emissions by 66% to 7.3 kg CO2-eq./kg meat in the most intensive system and by 100% in the most extensive system. In this calculation a carbon sequestration
rate of 8 t CO2/ha/year was assumed. The potential of a combination of the addition of lipids to the diet, a cover of the slurry tank and
the application of nitrification inhibitors only had the potential to reduce GHG emissions by 12% thereby marginal abatement
costs are increasing much faster than for agroforestry systems. A reduction of the GHG emissions to 7.5 kg CO2-eq./kg meat—possible with agroforestry only—raised costs between 0.03 CHF/kg meat and 0.38 CHF/kg meat depending on the production
system and the state of the system before the reduction. If GHG emissions were reduced maximally average costs ranged between
0.37 CHF/kg meat, if agroforestry had the potential to reduce net GHG emissions to 0 kg CO2-eq., to 1.17 CHF/kg meat if also other options had to be applied. 相似文献