Adult-onset GM2 gangliosidosis diagnosed in a fetus

Amniocentesis and subsequent tests are reported on a fetus conceived of a rare mating type: its mother has an intermediate level of β hexosaminidase A (HEX A), characteristic of carriers of Tay-Sachs disease (TSD), while the father suffers from an adult-onset GM₂ ganglio-sidosis (AOG) with severe HEX A deficiency. Activity of HEX A in the cultured fetal cells was very low when measured by the heat-inactivation method, thus showing the typical biochemical phenotype of TSD fetuses. However, upon separation of HEX isozymes by ion exchange chromatography, residual HEX A (17 per cent of total HEX) was demonstrated. Also in contrast to TSD fetuses, this fetus' fibroblasts were able to synthesize the precursor of a chains of HEX, and ultrastructural examination of its brain revealed few atypical lamellar bodies, unlike those found in TSD fetuses of the same gestational age. It is therefore concluded that the fetus was not affected with TSD, but rather with AOG.     

Factor structure of the transformational leadership model in human service teams

The purpose of this study was to examine the factor structure of the transformational leadership model in human service teams. As the nature of this work environment mandates certain management‐by‐exception practices, patterns of correlations between perceptions of active and passive management‐by‐exception behaviors and transformational, transactional, and laissez‐faire leadership were of interest. 236 leaders and 620 subordinates from 54 mental health teams completed the Multifactor Leadership Questionnaire, form 8Y. Results suggest that active and passive management‐by‐exception factors are independent constructs. Copyright © 2003 John Wiley & Sons, Ltd.     

COMPARATIVE STUDY OF OPTIMIZATION TECHNIQUES FOR IRRIGATION PROJECT PLANNING1

ABSTRACT: This study presents three optimization techniques for on‐farm irrigation scheduling in irrigation project planning: namely the genetic algorithm, simulated annealing and iterative improvement methods. The three techniques are applied to planning a 394.6 ha irrigation project in the town of Delta, Utah, for optimizing economic profits, simulating water demand, and estimating the crop area percentages with specific water supply and planted area constraints. The comparative optimization results for the 394.6 ha irrigated project from the genetic algorithm, simulated annealing, and iterative improvement methods are as follows: (1) the seasonal maximum net benefits are $113,826, $111,494, and $105,444 per season, respectively; and (2) the seasonal water demands are 3.03*10³ m³, 3.0*10³ m³, and 2.92*10³ m³ per season, respectively. This study also determined the most suitable four parameters of the genetic algorithm method for the Delta irrigated project to be: (1) the number of generations equals 800, (2) population size equals 50, (3) probability of crossover equals 0.6, and (4) probability of mutation equals 0.02. Meanwhile, the most suitable three parameters of simulated annealing method for the Delta irrigated project are: (1) initial temperature equals 1,000, (2) number of moves equal 90, and (3) cooling rate equals 0.95.     

Cultural and individual differences in self‐rating behavior: an extension and refinement of the cultural relativity hypothesis

This study examined the relationships between culture, individual attributes, and self‐rating behavior among 1,786 university students in Canada, Hong Kong, Taiwan, mainland China, and Japan, and in doing so extended and refined the cultural relativity hypothesis. It explored the difference between vertical and horizontal individualists in self‐rating behavior, and examined the mediating effects of two individual attributes, self‐enhancement propensity and general self‐efficacy in the relationship between individualism and self‐rating behavior. The results confirmed that individualism is the cultural driver for self‐rating leniency, and that the individual‐level assessment of individualism is a stronger predictor of self‐rating leniency than are culture‐level differences. Vertical individualism was found to be positively related to self‐enhancement propensity, which in turn was positively related to self‐rating. Whereas, horizontal individualism was positively related to general self‐efficacy, which in turn had a positive relationship with self‐rating. We discuss the implications of the results for academic research and practical management. Copyright © 2006 John Wiley & Sons, Ltd.     

Emotional social support and job burnout among high‐school teachers: is it all due to dispositional affectivity?

The authors investigated whether the relationship between the contents of emotional social support and job burnout among high‐school teachers is spurious because of the role of dispositional positive and negative affectivity. A national sample of 339 teachers was surveyed via a web‐based procedure. Hierarchical regression analyses did not support spuriousness; emotional social support was uniquely predictive of three dimensions of burnout controlling for affectivity. As positive emotional social support increased, emotional exhaustion and cynicism decreased, and professional efficacy increased. As negative emotional social support increased, emotional exhaustion and cynicism also increased. Commonality analyses based on the present data and data reported by K. L. Zellars and P. L. Perrewé (2001; Journal of Applied Psychology, 86, 459–467) provided additional support for the unique role of emotional social support on burnout, but these analyses suggest a greater role of affectivity than emotional social support. These findings have implications for research on burnout as well as the prevention of burnout among teachers. Copyright © 2006 John Wiley & Sons, Ltd.     

Remediation of acid mine drainage leachate by a physicochemical and biological treatment‐train approach

Biological and physicochemical approaches were utilized in a treatment train for acid mine dis charge (AMD) waters. Anaerobic bioreactors, chemical precipitation reactors, and biopolymer chelation reactors, operated in static, semicontinuous, and continuous flow modes, removed significant quantities of metals and sulfates associated with AMD water. Static tests indicated accept able copper removal via precipitation by generation of hydrogen sulfide in anaerobic reactors. However, low pH affected the biopolymer coating in the chelation reactor, resulting in loss of bed surface. Corrections of AMD to pH > 7 resulted in some metal precipitationprior to biopolymer treatment. A series of static semicontinuous tests at pH 5.0 provided improved metal and sulfate removal. Copper (Cu⁺) was reduced to trace concentrations, while manganese (Mn⁺), although reduced, proved to be the most recalcitrant of the metals. © 2006 Wiley Periodicals, Inc.