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61.
Environmental Science and Pollution Research - Antibiotics are frequently used in the dairy sector for prophylactic uses along with therapeutic purposes. Throughout the globe, antibiotic resistance...  相似文献   
62.
Environmental Science and Pollution Research - Nowadays, the use of different nanoscale structures has been introduced to a large number of research areas. One of these is the treatment and...  相似文献   
63.
Environmental Science and Pollution Research - Nutrient source and transport study in tropical creeks adjacent to megacities are sparse on a regional and global scale. High-frequency chemical data...  相似文献   
64.
Environmental Science and Pollution Research - Mitochondria are unique cell organelles, which exhibit multifactorial roles in numerous cell physiological processes, significantly...  相似文献   
65.
Environmental Science and Pollution Research - Carbon porous materials obtained through KOH activation of a furfural?+?hydroquinone?+?urotropine mixture were applied as...  相似文献   
66.

Free radical or oxidative stress may be a fundamental mechanism underlying several human neurologic diseases. Therapy using free radical scavengers (antioxidants) has the potential to prevent, delay, or ameliorate many neurologic disorders. However, the biochemistry of oxidative pathobiology is complex, and optimum antioxidant therapeutic options may vary and need to be tailored to individual diseases. In vitro and animal model studies support the potential beneficial role of various antioxidant compounds in neurological disease. Antioxidants generally play an important role in reducing or preventing the cell damage and other changes which occur in the cells like mitochondrial dysfunction, DNA mutations, and lipid peroxidation in the cell membrane. Based on their mechanism of action, antioxidants can be used to treat various neurological disorders like Huntington’s disease, Alzheimer’s disease, and Parkinson’s disease. Vitamin E has a scavenging action for reactive oxygen species (ROS) and also prevents the lipid peroxidation. Creatine generally reduces the mitochondrial dysfunction in Parkinson’s disease (PD) patients. Various metal chelators are used in PD for the prevention of accumulation of the metals. Superoxidase dismutase (SOD), lipases, and proteases act as repair enzymes in patients with AD. Accordingly, the antioxidant defense system is found to be most useful for treating various neurological disorders.

  相似文献   
67.
Environmental Science and Pollution Research - Exposure to environmental pollutants has been associated with alteration on relative levels of mitochondrial DNA copy number (mtDNAcn). However, the...  相似文献   
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69.
Environmental Science and Pollution Research - A novel fabrication of magnetite (Fe3O4) nanochains, surface functionalized with glutathione (GSH), has been attempted through a basic wet reduction...  相似文献   
70.
A field experiment was conducted to study the effect of different amendments of tannery sludge on physiological and biochemical parameters of tomato plant (Lycopersicon esculentum L. Mill). The accumulation of metals (Cr, Fe) in different parts of tomato plants grown on tannery sludge amended soil increased in a concentration and duration-dependent manner. The accumulation of both the metals was found lowest in the fruits of the plant. The statistical analysis of the results showed an increase in chlorophyll and protein contents in lower sludge amendment ratio at all exposures followed by a decrease at highest (100%) sludge amendment ratio. Lipid peroxidation enhanced in both root and leaves of sludge grown plants of tomato at all the sludge amendments and exposure periods, which is evidenced by increased malondialdehyde content, however the maximum increase was found in the roots (43.63%) and leaves (56.66%) of the plant grown on 100% tannery sludge at 60 d, over respective controls. The level of antioxidants, cysteine, non-protein thiol and ascorbic acid increased in the sludge grown plants of tomato to cope up with stress induced by the excess amount of the heavy metals present in the tannery sludge. The maximum increase was found in cysteine content (75.53% in the leaves), non-protein thiol content (92.68% in the roots) and ascorbic acid content (29.66% in the roots) of the plant at 75% tannery sludge after 30 d. The tomato plants were found well adopted for minimizing damage induced by reactive oxygen species, when grown on tannery sludge amendments in the present study.  相似文献   
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