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A case of confined placental mosaicism (CPM) and maternal uniparental isodisomy 14 identified after placental karyotype revealed trisomy 14 in a newborn with intrauterine growth restriction (IUGR) and minor dysmorphic features is reported. During the second trimester of the pregnancy, multiple marker screening revealed an increased risk for Down syndrome of >1 in 10. The maternal serum human chorionic gonadotrophin (MShCG) was markedly elevated at 4.19 MoM. Amniocentesis revealed a normal 46,XX karyotype. Fetal growth restriction has been associated with elevated MShCG and placental aneuploidy with CPM for chromosomes 2, 7, 9 and 16. The present case of CPM for chromosome 14 was also associated with fetal growth restriction and elevated second trimester MShCG, suggesting a common link. Further studies need to be done to determine if indeed elevation of second trimester MShCG is associated with increased risk of CPM. The present case again demonstrates the need to perform placental karyotype in unexplained fetal growth restriction. Copyright © 2001 John Wiley & Sons, Ltd. 相似文献
23.
Sam StroichJr. 《Conservation biology》1996,10(2):315-315
24.
Sam H. Johnson Alan C. Early Max K. Lowdermilk 《Journal of the American Water Resources Association》1977,13(6):1253-1268
ABSTRACT: Examples are drawn from the Indus Basin to explain why on-farm water management problems restrict the output of agricultural products in many LDC's. Data is presented to illustrate the low level of water management knowledge of both the farmers and the current extension agents. Examples of the level of corruption and its effect on the operating system are illustrated. Several requirements that must be met before a large-scale irrigation scheme will actually increase the welfare of LDC's farmers are presented. 相似文献
25.
Peng LianXiaodan Gao M. Sam Mannan 《Journal of Loss Prevention in the Process Industries》2012,25(1):103-113
Flammable aerosols have created many fire and explosion hazards in the process industry, but the flammability of aerosols has not been fully understood. The minimum ignition energy has been widely used as an indicator for flammability of combustible mixtures, but the amount of experimental data on the minimum ignition energy of aerosols is very limited. In this work, the minimum ignition energy of tetralin aerosols is predicted using an integrated model. The model applies the flame front propagation theory in aerosol systems to the growth of the flame kernel, which was created during the spark discharge in the ignition process. The aerosol minimum ignition energy was defined as the minimum level of energy in the initial flame kernel to maintain the kernel temperature above the minimum ignition temperature of 1073 K specific for tetralin aerosols during the kernel growth. The minimum ignition energy obtained in the model is influenced by the fuel-air equivalence ratio and the size of the aerosol droplets. For tetralin aerosols of 40 μm diameter, Emin decreases significantly from 0.32 mJ to 4.3 × 10 e−3 mJ when the equivalence ratio rises from 0.57 to 1.0. For tetralin aerosols of 0.57 equivalence ratio, Emin increases from as 0.09 mJ to 0.32 mJ when the droplet diameter rises from 10 μm to 60 μm. The trends are in agreement with previous experimental observations. The method used in current work has the potential to prediction of the minimum ignition energy of aerosol. 相似文献
26.
Christian Diaz-Ovalle Richart Vazquez-Roman Raul Lesso-Arroyo M. Sam Mannan 《Journal of Loss Prevention in the Process Industries》2012,25(6):974-981
Curtain mitigation systems are modeled here since they have experimentally shown their efficiency in reducing the concentration of certain toxic gases within dense gas clouds. Air, water and steam are analyzed in a model as the physical barriers to decrease the gas concentration. The model, developed for a steady-state mitigation process, is based on the mass, energy and momentum conservation laws. Concentration estimations during the dispersion before and after the mitigation are performed with a SLAB type model. A sensitivity analysis for each model is given to detect which variables have bigger effects. A release of chlorine is used as an example and the results are calculated in a prototype developed in Visual C++, where the model is solved using the Runge–Kutta 4th order method. The results include the effects of composition, speed, temperature and height of the releasing point as well as a comparison with CFD simulations. The proposed model is simplified and it cannot reproduce eddy effects but it is fast and robust enough. The model provides a set of equations that can be used in numerical problems where explicit derivatives are required, e.g. optimizations procedures. 相似文献
27.
Alba Pineda-Solano Lina Saenz-Noval Subramanya Nayak Simon Waldram Maria Papadaki M. Sam Mannan 《Process Safety and Environmental Protection》2012,90(5):404-410
Alkylpyridine N-oxides are important intermediates in the pharmaceutical and agrochemicals industries. The N-oxides are produced via the homogeneously catalyzed oxidation of the respective alkylpyridines using a 50% excess of hydrogen peroxide. The competitive hydrogen peroxide decomposition produces oxygen in the flammable environment of alkylpyridines and thus forms a key hazard for this reaction. In this work, the N-oxidation was performed under pressure in the temperature range of 110–125 °C with different catalyst concentrations. It was shown that temperature had an undisputable positive effect on the N-oxidation efficiency. The accurate measurement of the pressure rise due to decomposition was difficult. However, only 5% of the added H2O2 decomposed when stoichiometric quantities were employed, even in the temperature of 110 °C. The N-oxidation was very efficient, even when the lowest concentration of catalyst employed in this study was used. 相似文献
28.
Michael J. Miller Sam Wouthuyzen Gen Minagawa Jun Aoyama Katsumi Tsukamoto 《Marine Biology》2006,148(5):1101-1111
A survey for leptocephali around Sulawesi Island in the central Indonesian Seas during May 2001 found that the leptocephali
of the congrid eel, Ariosoma scheelei, were present in all seven areas that were sampled. A total of 551 leptocephali (22–166 mm TL) were collected, and A. scheelei was by far the most abundant species of leptocephali collected during the survey. The wide range of sizes in most areas indicated
that spawning had occurred during a period of several months in many different areas, although the exact spawning locations
were not determined. The larger size classes were more abundant in all areas except in Tomini Bay on the northeast side of
Sulawesi Island. The highest catch rates were observed at the eastern edge of the Java Sea and to the north in the Celebes
Sea near Makassar Strait. Premetamorphic leptocephali were also collected in surface samples at 11 stations (N=62), but metamorphosing leptocephali (N=86) were only caught in IKMT tows that fished from the surface to about 200 m. Metamorphosing leptocephali were collected
primarily at two stations in the Java Sea and Makassar Strait where a surface layer of lower-salinity water was detected.
Their total lengths (105.3–153.3 mm) and the largest premetamorphic individuals suggested that this species can reach maximum
sizes of about 165 mm before beginning to metamorphose. It is hypothesized that this species may be abundant in the Indonesian
Seas region and that it has ecological traits such as large size at recruitment and a small size at reproduction that have
made it successful in many regions of the Indo-Pacific. 相似文献
29.
Sam Provoost Carole Ampe Dries Bonte Eric Cosyns Maurice Hoffmann 《Journal of Coastal Conservation》2004,10(1):33-42
Grey dunes are a priority habitat type of the European Union Habitats Directive and demand special attention for conservation
and management. Knowledge of the ecology of coastal grey dunes can contribute to this policy. Dune grassland succession is
initiated by fixation and driven by the complex of soil formation (humus accumulation) and vegetation development. Leaching
and mobilization of CaCO3. which are important in nutrient dynamics, complicate the picture. At present, grass- and scrub encroachment greatly overrules
these fine scaled soil processes and causes substantial loss of regional biodiversity. Belgium has an international responsibility
in grey dune conservation because of the limited range of its characteristic vegetation, flora and fauna. As biomass removal
seems essential in grassland preservation, grazing is an important management tool. Evaluation of management measures focuses
on biodiversity measurements on the levels of landscape, community and species. 相似文献
30.
Lipfert F Morris S Sullivan T Moskowitz P Renninger S 《Journal of the Air & Waste Management Association (1995)》2005,55(4):388-398
This paper considers several broad issues in the context of probabilistic assessment of the benefits of curtailing mercury (Hg) emissions from U.S. coal-fired power plants, based on information developed from recent literature and epidemiology studies of health effects of methylmercury. Exposure of the U.S. population is considered on the national scale, in large part because of recent questions arising from survey and experimental data about the relative importance of local deposition of airborne Hg. Although epidemiological studies have provided useful information, safe levels of Hg exposure remain uncertain, in part because of other dietary considerations in the populations that were studied. For example, much of the seafood consumed in one of the major studies was also contaminated with polychlorinated biphenyls, as are fish taken from some U.S. fresh waters. The primary epidemiological approach involves cross-study comparisons in relation to mean exposures, rather than detailed critiques of individual effects reported in each study. U.S. exposures are seen to be well below the levels at which adverse health effects are reported. This analysis supports the conclusion that unilateral reduction of Hg emissions from U.S. coal-fired power plants alone is unlikely to realize significant public health benefits. 相似文献