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241.
242.
M. M. Van Zalen-Sprock MD J. M. G. Van Vugt J. J. Van Der Harten H. P. Van Geijn 《黑龙江环境通报》1995,15(2):171-177
Two cases of sirenomelia are described, detected in the 14th and 16th weeks of gestation by transvaginal ultrasonography. A hypothesis for the aetiology of sirenomelia and its associated anomalies is discussed. 相似文献
243.
W. Lissens M. Van Lierde J. Decaluwe W. Foulon P. Evrard F. van Hoof M. Freund I. Liebaers 《黑龙江环境通报》1988,8(1):59-62
The X-linked Hunter syndrome or mucopolysaccharidosis II was diagnosed in a male fetus by demonstrating a severe deficiency of iduronate 2-sulphate sulphatase activity in fetal plasma obtained by umbilical fetal blood sampling at 23 weeks of pregnancy. The diagnosis was confirmed after termination of pregnancy. 相似文献
244.
Jiaen Liu Dr Willy Lissens Paul Devroey Andre Van Steirteghem Ingeborg Liebaers 《黑龙江环境通报》1993,13(9):873-880
The efficiency of the polymerase chain reaction (PCR) in detecting the cystic fibrosis (CF) ΔF508 mutation (which is the most common mutation of CF) was assessed in single human blastomeres. Twenty-one human immature oocytes (germinal-vesicle-stage oocytes) that had been donated for research were matured in vitro and a single spermatozoon from a carrier of the CF ΔF508 mutation was injected into the ooplasm. Fourteen embryos were obtained after intracytoplasmic sperm injection (ICSI). PCR analysis was carried out on 70 single blastomeres isolated from these 14 embryos. The results showed that the efficiency of DNA amplification by PCR in single nucleate blastomeres was 94 per cent (59/63). There were no false-positive results since none of the blank samples or the blastomeres without a nucleus showed an amplified signal. We found that nine embryos were homozygous for the unaffected genotype and that four embryos were heterozygous since they contained both the unaffected and the ΔF508 genotype. In a four-cell embryo, we observed the homozygous unaffected genotype in one blastomere and a heterozygous ΔF508/unaffected genotype in the other three blastomeres. 相似文献
245.
246.
Thuan Van Tran Duyen Thi Cam Nguyen Hanh T.N. Le Dai-Viet N. Vo Sonil Nand Trinh Duy Nguyen 《环境科学学报(英文版)》2020,32(7):137-150
Aquatic contamination of diclofenac (DCF), an emergent non-steroidal anti-inflammatory drug (NSAIDs), can result in adverse effects to many ecosystems through biomagnification. Hence, introducing effective remediation techniques to sequester the pharmaceutical wastes is highly fundamental to prevent their accumulation in the environment. Generally, adsorption has been presented as a green and efficient approach. Herein, we report the characterization and application of the novel magnetic nanocomposite ([email protected]2O4) derived from cobalt-based ferrite (CoFe2O4) and graphene oxide (GO) for DCF adsorption. For the optimization procedure, the response surface methodology (RSM) was adopted to investigate the impacts of DCF concentration (1.6–18.4 mg/L), DCF dosage (0.08–0.92 g/L), and solution pH (2.6–9.4) to find the optimum conditions for DCF removal, at 10.5 mg/L, 0.74 g/L, and pH 4, respectively. For the adsorption experiments, the kinetic, isotherm, thermodynamic, and intraparticle diffusion models were systematically studied. Moreover, we have elucidated the role of functional groups on the surface of [email protected]2O4 in enhancing the adsorption of DCF drug. With good removal efficiency (up to 86.1%), high maximum adsorption capacity (32.4 mg/g), [email protected]2O4 can be a potential candidate to eliminate DCF drug from water. 相似文献
247.
Jozien T. J. Brons Hans J. Van Der Harten Herman P. Van Geijn Juri W. Wladimiroff Martinus F. Niermeuer Dick Lindhout Patricia A. Stuart Chris J. L. M. Meijer Nico F. Th Arts 《黑龙江环境通报》1990,10(5):279-288
Radial-ray reduction malformations (RRRMs) may occur isolated or in association with other anomalies. The data of seven fetuses born with RRRMs were collected. Six fetuses had associated lethal abnormalities of the central nervous system, urogenital system, and/or heart, detected by ultrasound. In five cases, it was possible to establish the precise diagnosis, enabling an informed prognosis and subsequent genetic counselling. The diagnoses were: Edwards syndrome (n=3), VACTERL association (n=1), and Poland-Moebius-like complex (n= 1). In two cases, a complete diagnosis was not possible because of inadequate evaluation of these fetuses before and/or after birth. A proposal is given for the diagnostic approach for infants with RRRMs detected in the antenatal period by means of ultrasonography. 相似文献
248.
Intrauterine fetal death occurred in four women who were ‘screen-positive’ in a screening programme for neural tube defects (NTDs) and Down syndrome (DS). These women had very high levels of maternal serum alpha-fetoprotein (MSAFP) and maternal serum human chorionic gonadotropin (MShCG). Therefore, we evaluated all ‘screen-positive’ women in whom both of these markers were ⩾ 2.0 multiples of the median. The cases fulfilling these criteria totalled 11, and only one of them had no complications. High concentrations of both MSAFP and MShCG in a number of these cases might have been caused by an increased placental volume, which, in turn, might have been induced by decreased perfusion of the placenta. We conclude that screening programmes wrongly determine a high risk of fetal NTD or DS if the concentrations of both these parameters are very high. Invasive diagnostic procedures should be avoided in these cases, particularly in view of the increased risk of an adverse pregnancy outcome. 相似文献
249.
In this study, we present evidence that the invasive alga Codium fragile ssp. tomentosoides is chemically defended against grazing by a wound-activated chemical defense involving dimethylsulfoniopropionate (DMSP)
and the products of its cleavage, dimethylsulfide (DMS), and acrylic acid (AA). DMSP in C. fragile ssp. tomentosoides was present throughout the year, but concentrations varied seasonally and were highest in the winter. Intra-thallus variation
was neither large, nor consistent over time. High DMSP concentrations were uncommon among northwestern Atlantic macrophytes.
Of 26 other species tested, only two, Ulva lactuca and Polysiphonia harveyi contained concentrations comparable to, or higher than, those of C. fragile ssp. tomentosoides. DMS and AA, both individually and together, deterred grazing by the green sea urchin Strongylocentrotus droebachiensis at “natural” concentrations. These results suggest that DMS and AA contribute to the avoidance of C. fragile ssp. tomentosoides by S. droebachiensis. As a result, the production of DMSP and its subsequent cleavage, upon injury, may reduce herbivory on C. fragile ssp. tomentosoides and contribute to its success. 相似文献
250.
Initial ecological observations at Broken Spur in 1993 suggested a low biomass relative to other deep-water vent communities
known along the Mid-Atlantic Ridge. The persistence of a low shrimp biomass over 15 mo at Broken Spur vents appears to refute
the hypothesis that the community is expanding through reproduction and immigration to occupy habitat vacated during a recent
period of hydrothermal quiescence or catastrophe. Although the absence of “swarms” of shrimp similar to those found at the
hydrothermal mounds of TAG (26°N) and Snake Pit (23°N) is a visually striking feature of the majority of venting structures
known at Broken Spur, the biomass of fauna other than shrimp may not be significantly less than that of other Mid-Atlantic
sites. The discovery of “swarms” of shrimp at Bogdanov Site, visited for the first time in 1994, suggests that availability
of substratum exposed to the flow of hydrothermal fluids, which is a function of the topography of venting structures, may
be a prerequisite for the development of these dense aggregations. Two testable predictions arise from this hypothesis. Firstly,
dense aggregations of Rimicaris exoculata should occur at any other structures with a morphology similar to Bogdanov Site that may be discovered in the Broken Spur
vent field, and should not occur at other isolated chimney structures that may be found. Secondly, “swarms” of shrimp should
appear at any Broken Spur chimneys that develop into structures with a morphology more similar to that of Bogdanov Site in
future.
Received: 2 July 1997 / Accepted: 9 July 1997 相似文献