Evaluation of chlordimeform and degradation products for mutagenic and DNA‐damaging activity in salmonella typhimurium and escherichia coli

Abstract

The mutagenic activity of chlordimeform and two of its breakdown products, 4‐chloro‐o‐toludine and 4‐chloro‐N‐formyl‐o‐toluidine were determined with five histidine dependent strains of Salmonella typhimurium (TA1535, TA1537, TA1538, TA98, TA100) and five tryptophan dependent strains of E. coli WP₂. (WP₂, WP₂uvrA, WP67, CM611, CM571) with and without rat liver microsomal enzymes. 4‐chloro‐o‐toluidine increased the number of the reversions of the S. typhimurium strain TA1535 more than two fold over spontaneous at the concentration of 400 μg/plate.

The results of the DNA repair tests in the Salmonella TA1538/TA1978 and E. coli multirepair deficient systems showed that both breakdown products were active in inducing damage not repaired in at least one repair deficient strain while chlordimeform itself was inactive.     

Urban Flood Problems in Dhaka,Bangladesh: Slum Residents’ Choices for Relocation to Flood-Free Areas

This article applies a stated preference choice model to assess trade-offs that residents of two squatter settlements in Dhaka, Bangladesh might consider if they were given choices for relocation to flood-free areas. The respondents were asked to choose repeatedly from a set of choice cards, which displayed different configurations of financial incentives for relocation, such as free or inexpensive land, loans or nonrepayable grants, and provisions for temporary or permanent employment opportunities. The survey results indicated that despite extensive experience with flood problems, many residents of Mirpur and Vasantek found that certain configurations of economic incentives were not attractive enough for them to relocate to flood-free areas. At the same time, they would prefer a reduction in the risk of flooding at their current location. The economic incentives that would best assist in increasing voluntary relocation of residents from their current locations included free land, nonrepayable grants (Taka 20,000), and long-term employment opportunities. Further, differences in geographic location (i.e., Mirpur vs. Vasantek), income levels, and membership in neighborhood communities were linked with the tendency of residents to stay at their current location.     

Ferric-manganese doped sulphated zirconia nanoparticles catalyst for single-step biodiesel production from waste cooking oil: Characterization and optimization

Biodiesel of waste cooking oil origin is gaining attention as a replacement for current fossil fuels, as its low-priced, recycled feedstock shall prevent food source competition, which is estimated to happen with current biodiesel production processes. As a result, waste cooking oil has been claimed to be a highly potential feedstock for biodiesel production. In the present research work, Fe-Mn doped sulphated zirconia catalyst was synthesized and used in simultaneous esterification and transesterification of waste cooking oil to biodiesel synthesis. The catalyst was prepared through the impregnation method and characterized by using XRD, TPD-NH_3, FT-IR, BET, and TEM. Response surface methodology (RSM) in conjunction with the central composite design (CCD) was applied to statistically evaluate and optimize the biodiesel preparation process. It was found that the synthesis of biodiesel achieved an optimum level of 97.2% waste cooking oil methyl ester’s (WCOME’s) yield at the following reaction conditions: methanol/oil molar ratio: 10:1, catalyst concentration: 3.0 wt %, and reaction temperature: 160 °C. The extremely high WCOME’s yield of 97.2% was proved to be due to high acidity, surface area, and large pore diameter; reactants can easily diffuse into the interior pore of the catalyst and allow them to be in contact with active sites that enhance catalytic activity.     

Impact of population dynamics on Margalla Hills Ecosystem:a community-level case study

Margalla Hills National Park(MHNP) is a declared natural reserve of Pakistan,and Saidpur village is located at its foothills.To sustain livelihood,Saidpur community relies on natural resources and has established an intriguing relationship with the surrounding ecosystem.Human intrusion and related impacts were investigated through self-structured questionnaire from village community to gather information about demography,life practices,natural resource use,and their perception about the environment.Quadrat analysis revealed that the overall plant density was<4 plants/m~2,whereas ordination biplot has indicated significant reduction in plant cover and sparse distribution of species in areas close to human settlement.Survey results show that more than 50%families rely on forest wood as fuel source.Logistic regression has identified education paucity(odds ratio,OR=2.6,95%confidence interval,CI=1.0-6.7),large family size(OR= 5.0,95%CI=1.5-16.6),and fuel type(OR=3.5,95%CI=1.2-9.9)as significant predictors of accelerated forest cutting in MHNP.Male members were mostly illiterate and in favor to promote construction activities which reflects their low concern and casual attitude toward resource conservation.In this study,lack of awareness and peoples’ dependency on natural resources emerged as priority challenges,and hence,we suggest provision of alternate fuel sources,better education and sustained income resources as incentives to bring behavioral change.It is pivotal to involve local community before the adoption of any conservation plan as intervention strategy to protect MHNP ecosystem.     

The impact of carbon pricing,climate financing,and financial literacy on COVID-19 cases: go-for-green healthcare policies

Environmental Science and Pollution Research - Climate finance and carbon pricing are regarded as sustainable policy mechanisms for mitigating negative environmental externalities via the...     

Spatio-temporal assessment of land use dynamics and urbanization: linking with environmental aspects and DPSIR framework approach

Environmental Science and Pollution Research - Urbanization is the main force of the global environmental as well as land use land cover changes (LULC). Urbanization is caused by prompt increase in...     

Spatial�Ctemporal assessment and redesign of groundwater quality monitoring network: a case study

Assessment of groundwater quality monitoring networks requires methods to determine the potential efficiency and cost-effectiveness of the current monitoring programs. To this end, the concept of entropy has been considered as a promising method in previous studies since it quantitatively measures the information produced by a network. In this study, the measure of transinformation in the discrete entropy theory and the transinformation?Cdistance (T?CD) curves, which are used frequently by other researchers, are used to quantify the efficiency of a monitoring network. This paper introduces a new approach to decrease dispersion in results by performing cluster analysis that uses fuzzy equivalence relations. As a result, the sampling (temporal) frequency determination method also recommends the future sampling frequencies for each location based on certain criteria such as direction, magnitude, correlation with neighboring stations, and uncertainty of the concentration trend derived from representative historical concentration data. The proposed methodology is applied to groundwater resources in the Tehran?CKaradj aquifer, Tehran, Iran.     

Scenarios for investigating the future of Canada’s oceans and marine fisheries under environmental and socioeconomic change

Regional Environmental Change - There is a critical need to develop effective strategies for the long-term sustainability of Canada’s oceans. However, this is challenged by uncertainty over...