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1.
Dale Hattis John M. Wasson Guy S. Page Bonnie Stern Claire A. Franklin 《Journal of the Air & Waste Management Association (1995)》2013,63(9):1060-1066
This paper explores some detailed mechanistic hypotheses for the possible action of acid particles on the tracheobronchial region of the human respiratory system. Because of the buffering capacity and volume of mucus produced per day it appears doubtful that ordinary ambient exposures to acid particles could markedly change the overall pH of tracheobronchial mucus considered as a whole. However it is possible that individual acidic particles could contain enough acid to deliver localized “irritant signals” that could be the triggers for enhanced mucus secretion and cell division in sensitive portions of the bronchial tree, and thereby contribute to the processes involved in chronic bronchitis. Depending on the exact pH depression required for a “signal” to be perceived by the tracheobronchial epithelium, the acid content of the incoming particles per unit weight, and the effect of neutralization by ammonia in the upper respiratory tract, the minimum size of an acidic particle required to deliver a perceptible signal might range from about 0.4 to 0.7 microns for portions of the epithelium that are frequently swept by 4-micron mucus droplets. (For unprotected epithelium, however, it is conceivable that the minimum effective size for acid particles could be less.) Since particle number per unit weight declines dramatically with increasing particle size, the most potent fraction of particles in terms of signals delivered per μg/m3is likely to be just above the minimum size that is needed to produce an effective signal. The model developed here makes predictions of the relative potency of particles of different size and acid delivery capacity that could be tested in both experimental animal systems and human epidemiological studies. 相似文献
2.
We demonstrate a materials budget approach to identify the main source areas and fluxes of pathogens through a landscape by using the flux of fine sediments as a proxy for pathogens. Sediment budgets were created for three subcatchment tributaries of the Googong Reservoir in southeastern New South Wales, Australia. Major inputs, sources, stores, and transport zones were estimated using sediment sampling, dam trap efficiency measures, and radionuclide tracing. Particle size analyses were used to quantify the fine-sediment component of the total sediment flux, from which the pathogen flux was inferred by considering the differences between the mobility and transportation of fine sediments and pathogens. Gullies were identified as important sources of fine sediment, and therefore of pathogens, with the pathogen risk compounded when cattle shelter in them during wet periods. The results also indicate that the degree of landscape modification influences both sediment and pathogen mobilization. Farm dams, swampy meadows and glades along drainage paths lower the flux of fine sediment, and therefore pathogens, in this landscape during low-flow periods. However, high-rainfall and high-flow events are likely to transport most of the fine sediment, and therefore pathogen, flux from the Googong landscape to the reservoir. Materials budgets are a repeatable and comparatively low-cost method for investigating the pathogen flux through a landscape. 相似文献
3.
Guo Z Mosley RB Wasson SJ Fortmann RC McBrian JA 《Journal of the Air & Waste Management Association (1995)》2001,51(4):616-622
As an odorless, nontoxic, and inert compound, sulfur hexafluoride (SF6) is one of the most widely used tracer gases in indoor air quality studies in both controlled and uncontrolled environments. This compound may be subject to reactions with water vapor under elevated temperature to form acidic inorganic compounds such as HF and H2SO4. Thus, in the presence of unvented combustion sources such as kerosene heaters, natural gas heaters, gas log fireplaces, candles, and lamps, the SF6 dissociation may interfere with measurements of the emissions from these sources. Tests were conducted in a research house with a vent-free natural gas heater to investigate these potential interferences. It was observed that the heater operation caused about a 5% reduction of SF6 concentration, which can be an error source for the ventilation rate measurement and consequently the estimated pollutant emission rates. Further analysis indicates that this error can be much greater than the observed 5% under certain test conditions because it is a function of the ventilation flow rate. Reducing the tracer gas concentration has no effect on this error. A simple theoretical model is proposed to estimate the magnitude of this error. The second type of interference comes from the primary and secondary products of the SF6 dissociation, mainly H2SO4, SO2, HF, and fine particulate matter (PM). In the presence of approximately 5 ppm SF6, the total airborne concentrations of these species increased by a factor of 4-10. The tests were performed at relatively high SF6 concentrations, which is necessary to determine the interferences quantitatively. The second type of interference can be significantly reduced if the SF6 concentration is kept at a low ppb level. 相似文献
4.
In many vertebrates, environmental factors influence gamete differentiation and growth of the mature gonad through alteration
of sex steroid production or action; however, it is unclear how gamete differentiation and gonadal growth are regulated in
echinoids. The purpose of this study was to examine the influence of dietary administration of estradiol (E2), progesterone
(P4), testosterone (T) and finasteride (F, a 5α-reductase inhibitor) on the ovaries and testes of mature Lytechinus variegatus (Lamarck) during gonadal growth. Echinoids were fed a formulated diet supplemented with steroids or steroids in combination
with finasteride for 36 d. The effects of dietary administration of steroids on L. variegatus were both steroid- and sex-specific. The mean ovary index was 54% greater in individuals fed E2 than from individuals fed
the control (C) diet (10.0 ± 1.1 vs 6.5 ± 0.7, respectively; P < 0.05). Individuals fed E2, P4, E2/P4, and P4 in combination with F had significantly smaller oocytes (P < 0.005) than individuals fed C. The volume fraction occupied by nutritive phagocytes in ovarian tubules from individuals
fed E2/P4 or P4 were significantly larger than the volume fraction occupied by nutritive phagocytes from individuals fed C,
indicating that E2 and 5α-reduced progestins may promote nutrient allocation to nutritive phagocytes. Although oocytes from
the individuals fed T alone were significantly smaller than those fed T in combination with F, oocytes from individuals in
both treatments were significantly larger compared to oocytes from individuals fed C. These data suggest that upon removal
of 5α-reduced androgens, T is able to promote an increase in oocyte diameters. In contrast, the mean testis index was 56%
greater in individuals fed P4 than in individuals fed C (8.9 ± 0.6 vs 5.7 ± 0.9, respectively; P < 0.05); the testis index did not increase in individuals fed P4/F, suggesting that 5α-reduced progestins stimulate testicular
growth. Testes growth in the presence of 5α-reduced progestins was accomplished by significant increases in the volume fraction
occupied by nutritive phagocytes and by a significant reduction in the volume fraction occupied by spermatogenic columns in
testicular tubules. These data further indicate that 5α-reduced progestins (or 5α-reduced androgens) may inhibit spermatogenic
column formation. In conclusion, E2 stimulated ovarian growth but inhibited oocyte growth, whereas T had no affect on ovarian
growth but promoted oocyte growth in L. variegatus. We hypothesize that the E2 (or E2 metabolites) and/or 5α-reduced androgens in combination with T regulate oocyte growth
in the echinoid L. variegatus. In addition, 5α-reduced progestins promoted nutrient accumulation in nutritive phagocytes within the ovaries and the testes.
Furthermore, 5α-reduced progestins stimulated growth of the testes and inhibited spermatogenic column formation, suggesting
that 5α-reduced progestins regulate nutrient accumulation into nutritive phagocytes and spermatogenic column formation in
L. variegatus. The differences in estrogen effects between echinoids and asteroids may be related to differences in gonad morphology and,
ultimately, the differences in cellular signalling pathways (paracrine vs endocrine).
Received: 22 May 1999 / Accepted: 24 May 2000 相似文献
5.
Methods for defining and retrieving reference conditions for large rivers were explored with emphasis on hydromorphologic
and biologic quality indicators. For a set of four large rivers in the European Western Plains ecoregion, i.e., the rivers
Meuse, Loire, Allier, and Dordogne, reference reaches were selected based on geomorphologic characteristics. A survey of riparian
land use, vegetation, and bed geometry was done for the selected reaches. Responses of the riparian landscape to hydromorphologic
conditions were determined with a set of existing and newly developed measures of riparian dynamics and forest development.
Strong correlations were observed at the reach and local levels between the ratios of width to depth and embankment and the
developed measures of riparian dynamics and forest. Boundary conditions for riparian forest development were determined for
the hydromorphologic and biologic indicators of riparian dynamics and vegetation structure. These conditions also proved useful
for determining the presence of sustainable populations of Populus nigra and Salix purpurea. From this agreement between abiotic and biotic boundary conditions, a set of useful reference conditions was determined,
and a framework for the definition of reference and good status conditions subsequently evolved. Finally, a proposal for assessment
and monitoring the proposed indicators is discussed for its applicability. 相似文献
6.
Sourcing sediment using multiple tracers in the catchment of Lake Argyle,Northwestern Australia 总被引:5,自引:0,他引:5
Control of sedimentation in large reservoirs requires soil conservation at the catchment scale. In large, heterogeneous catchments,
soil conservation planning needs to be based on sound information, and set within the framework of a sediment budget to ensure
that all of the potentially significant sources and sinks are considered.
The major sources of sediment reaching the reservoir, Lake Argyle, in tropical northwestern Australia, have been determined
by combining measured sediment fluxes in rivers with spatial tracer-based estimates of proportional contributions from tributaries
of the main stream entering the lake, the Ord River. The spatial tracers used are mineral particle magnetics, the strontium
isotopic ratio, and the neodymium isotopic ratio. Fallout of 137Cs has been used to estimate the proportion of the sediment in Lake Argyle eroded from surface soils by sheet and rill erosion,
and, by difference, the proportion eroded from subsurface soils by gully and channel erosion. About 96% of the sediment in
the reservoir has come from less than 10% of the catchment, in the area of highly erodible soils formed on Cambrian-age sedimentary
rocks. About 80% of the sediment in the reservoir has come from gully and channel erosion. A major catchment revegetation
program, designed to slow sedimentation in the reservoir, appears to have had little effect because it did not target gullies,
the major source of sediment. Had knowledge of the sediment budget been available before the revegetation program was designed,
an entirely different approach would have been taken. 相似文献
7.
Brian K. Gullett William P. Linak Abderrahmane Touati Shirley J. Wasson Staci Gatica Charles J. King 《Journal of Material Cycles and Waste Management》2007,9(1):69-79
Air emissions and residual ash samples were collected and analyzed during experiments of open, uncontrolled combustion of
electronic waste (e-waste), simulating practices associated with rudimentary e-waste recycling operations. Circuit boards
and insulated wires were handled separately to simulate processes associated with metal recovery. The average emissions of
polychlorinated dibenzodioxins and dibenzofurans (PCDD/PCDFs) were 92 ng toxic equivalency (TEQ)/kg [n = 2, relative standard deviation (RSD) = 98%] and 11 900 ng TEQ/kg (n = 3, RSD = 50%) of the initial mass of the circuit boards and insulated wire, respectively. The value for the insulated wire
is about 100 times higher than that for backyard barrel burning of domestic waste. The emission concentrations of polybrominated
dibenzodioxins and dibenzofurans (PBDD/PBDFs) from the combustion of circuit boards were 100 times higher than for their polychlorinated
counterparts. Particulate matter (PM) sampling of the fly ash emissions indicated PM emission factors of approximately 15
and 17 g/kg of the initial mass for the circuit boards and insulated wire, respectively. Fly ash samples from both types of
e-waste contained considerable amounts of several metallic elements and halogens; lead concentrations were more than 200 times
the United States regulatory limits for municipal waste combustors and 20 times those for secondary lead smelters. Leaching
tests of the residual bottom ash showed that lead concentrations exceeded U.S. Environmental Protection Agency landfill limits,
designating this ash as a hazardous waste. 相似文献
8.
The mountain-lowland debate: deforestation and sediment transport in the upper Ganga catchment 总被引:1,自引:0,他引:1
Wasson RJ Juyal N Jaiswal M McCulloch M Sarin MM Jain V Srivastava P Singhvi AK 《Journal of environmental management》2008,88(1):53-61
The Himalaya-Gangetic Plain region is the iconic example of the debate about the impact on lowlands of upland land-use change. Some of the scientific aspects of this debate are revisited by using new techniques to examine the role of deforestation in erosion and river sediment transport. The approach is whole-of-catchment, combining a history of deforestation with a history of sediment sources from well before deforestation. It is shown that deforestation had some effect on one very large erosional event in 1970, in the Alaknanda subcatchment of the Upper Ganga catchment, but that both deforestation and its effects on erosion and sediment transport are far from uniform in the Himalaya. Large magnitude erosional events occur for purely natural reasons. The impact on the Gangetic Plain of erosion caused by natural events and land cover change remains uncertain. 相似文献
9.
10.
Mapped environmental classifications are defined using various procedures, but there has been little evaluation of the differences
in their ability to discriminate variation in independent ecological characteristics. We tested the performance of environmental
classifications of the streams and rivers of France that had been defined from the same environmental data using geographic
regionalization and numerical classification of individual river valley segments. Test data comprised invertebrate assemblages,
water chemistry, and hydrological indexes obtained from sites throughout France. Classification performance was measured by
analysis of similarity (ANOSIM). Geometric regions defined by a regular grid and without regard to environmental variables
and a posteriori classifications based on clustering the test datasets defined lower and upper bounds of performance for a
given number of classes. Differences in classification performances were generally small. The ANOSIM statistics for the a
posteriori classifications were around twice that of all environmental classifications, including geometrically defined regions.
The hydro-ecoregions performed slightly better for the invertebrate data and the network classification performed slightly
better for the chemistry and hydrological data. Our results indicate that environmental classifications that are defined using
different procedures can be comparable in terms of their ability to discriminate variation of ecological characteristics and
that alleged differences in performance arising from different classification procedures can be small relative to unexplained
variation. We conclude that definition procedures might have little effect on the performance of large-scale environmental
classifications and decisions over which procedures to use should be based primarily on pragmatic considerations. 相似文献