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The main organic wastes produced in modern wine industries include grape pomace (62%), lees (14%), stalk (12%) and dewatered sludge (12%). Some of these wastes are being used as by-products (grape pomace and lees) whereas the rest of organic wastes (stalk and wastewater sludge) has been traditionally incinerated or disposed in landfill. In this work, composting is proposed for the recovery of stalk and wastewater sludge to produce a sanitized organic amendment for application in the vineyard, closing the organic matter cycle. The environmental and economical analyses of the different alternatives to manage organic wastes from the wine industry are also presented. Composting costs are almost negligible when compared to other management options. From the environmental point of view, in-situ composting presents the best performance in 8 of the 10 impact categories analysed. Finally, the energy balance shows that the 4 composting systems involved less energy than the systems based on Mineral Fertilizer consumption.  相似文献   
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Environmental impacts and gaseous emissions associated to home and industrial composting of the source-separated organic fraction of municipal solid waste have been evaluated using the environmental tool of life cycle assessment (LCA). Experimental data of both scenarios were experimentally collected. The functional unit used was one ton of organic waste. Ammonia, methane and nitrous oxide released from home composting (HC) were more than five times higher than those of industrial composting (IC) but the latter involved within 2 and 53 times more consumption or generation of transport, energy, water, infrastructures, waste and Volatile Organic Compounds (VOCs) emissions than HC. Therefore, results indicated that IC was more impacting than HC for four of the impact categories considered (abiotic depletion, ozone layer depletion, photochemical oxidation and cumulative energy demand) and less impacting for the other three (acidification, eutrophication and global warming). Production of composting bin and gaseous emissions are the main responsible for the HC impacts, whereas for IC the main contributions come from collection and transportation of organic waste, electricity consumption, dumped waste and VOCs emission. These results suggest that HC may be an interesting alternative or complement to IC in low density areas of population.  相似文献   
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Early onset fetal growth restriction (FGR) may be due to impaired placentation, environmental or toxic exposure, congenital infections or genetic abnormalities. Remarkable research, mainly based on retrospective series, has been published on the diverse genetic causes. Those have become more and more relevant with the improvement in the accuracy of the analysis techniques and the rising of breakthrough genomewide methods such as the whole genome sequencing. However, no publication has presented an integrated view of management of those fetuses with an early and severe affection. In this review, we explored to which extent genetic syndromes can cause FGR fetuses without structural defects. The most common chromosomal abnormalities (Triploidies and Trisomy 18), submicroscopic chromosomal anomalies (22q11.2 microduplication syndrome) and single gene disorders (often associated with mild ultrasound findings) related to early and severe FGR had been analysed. Finally, we addressed the impact of epigenetic marks on fetal growth, a matter of growing importance. At the end of this review, we should be able to provide an adequate counseling to parents in terms of diagnosis, prognosis and management of those pregnancies.  相似文献   
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The ductus venosus (DV) is a tiny vessel leading oxygenated blood from the placenta to the fetal heart and its flow assessment has been used as an indicator of fetal acidemia. At 11 to 14 weeks, the fetuses with increased nuchal translucency also showing an abnormal DV blood flow were consistently found to be aneuploid. Early cardiac dysfunction, signaled by abnormal DV blood flow, was suggested as the underlying cause of increased nuchal translucency. Detection rates for aneuploidy with the use of DV blood flow studies range from 59 to 93% with 2 to 21% false-positive rates. In fetuses with normal karyotype, an abnormal DV flow pattern signals cardiac defects or adverse perinatal outcome. Copyright © 2004 John Wiley & Sons, Ltd.  相似文献   
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