流域水资源可持续开发利用中激励机制的应用

本文分析了流域水资源开发利用中存在的问题及原因，并根据可持续发展的理论，提出了流域水资源可持续开发利用的原则及相应的激励机制：①水价机制；②宏观调控机制；③水权机制；④相应的流域管理机制。     

面向台风事件与灾害影响评估的时空数据管理模式

准确掌握自然灾害致灾因子强度、影响范围以及持续时间等灾害事件与过程信息,是开展区域灾害预警预测、减灾救援以及灾后重建等工作的基础。目前还没有一种通用的时空数据模型,能够对台风等过程性自然灾害事件进行建模。以"201319"号"天兔"台风灾害事件为例,设计了一种基于元组时间标记法的台风灾害事件与过程的多尺度时空数据管理模式,并运用扩展SQL语言,将台风灾害影响区域等灾害事件的过程性信息按不同空间尺度同步存储,为台风灾害事件的历史回溯、数据共享与可视化以及风险区划等提供可靠、高效的过程数据管理方式。     

表观遗传学机制与空气污染的健康效应

空气污染是一个全球性的问题,并且具有深远的环境影响。暴露于空气污染会对人体健康产生许多不同的影响,理解空气污染的健康效应又是一个复杂命题,既要考虑不同类型的污染物同时也要考虑相关疾病的复杂性。然而越来越多的研究表明,表观遗传学在空气污染相关疾病的发生、发展中发挥着重要的作用。空气污染物可引起DNA甲基化、组蛋白修饰和miRNA表达等表观遗传学改变,这种改变往往发生在疾病产生的早期,因此相关研究不仅可以了解疾病的发病机制,而且还为疾病早期诊断和预防筛选可能的标志物。本文综述了表观遗传学的几种修饰方式和空气污染物造成不良健康损伤机制的一些研究进展。     

Biological removal of antiandrogenic activity in gray wastewater and coking wastewater by membrane reactor process

A recombinant human androgen receptor yeast assay was applied to investigate the occurrence of antiandrogens as well as the mechanism for their removal during gray wastewater and coking wastewater treatment. The membrane reactor (MBR) system for gray wastewater treatment could remove 88.0% of antiandrogenic activity exerted by weakly polar extracts and 97.3% of that by moderately strong polar extracts, but only 32.5% of that contributed by strong polar extracts. Biodegradation by microorganisms in the MBR contributed to 95.9% of the total removal. After the treatment, the concentration of antiandrogenic activity in the effluent was still 1.05 μg flutamide equivalence (FEQ)/L, 36.2% of which was due to strong polar extracts. In the anaerobic reactor, anoxic reactor, and membrane reactor system for coking wastewater treatment, the antiandrogenic activity of raw coking wastewater was 78.6 mg FEQ/L, and the effluent of the treatment system had only 0.34 mg FEQ/L. The antiandrogenic activity mainly existed in the medium strong polar and strong polar extracts. Biodegradation by microorganisms contributed to at least 89.2% of the total antiandrogenic activity removal in the system. Biodegradation was the main removal mechanism of antiandrogenic activity in both the wastewater treatment systems.     

Application of an enzyme-linked immunosorbent assay for the detection of clenbuterol residues in swine urine and feeds

The present study outlines applications of an enzyme-linked immunosorbent assay (ELISA) for the analysis of clenbuterol residues. Antisera were raised from rabbits immunized with diazotized clenbuterol-bovine serum albumin (BSA) conjugate. The assay was specific to clenbuterol with a half-maximum inhibition concentration (IC₅₀) of 1.8 ng/mL and 2.5 ng/mL in blank swine urine and phosphate buffer solution, respectively. The assay had high cross-reactivity (86%) with mabuterol, but low with other adrenergic agonists and antagonists. The average recovery of clenbuterol, as measured with the ELISA, ranged from 90% to 112% in swine urine samples and from 86% to 95% in feeds, respectively. This new assay was compared with commercial ELISA test kits. An excellent correlation (r ² = 0.98) between the two methods and satisfactory recoveries suggest that the new assay can be suitable for the determination of clenbuterol residues in real samples. The assay was used to analyze clenbuterol residues in 103 swine urine samples and 68 feed samples collected from northern China. Approximately 50% of the urine samples and 25% of the feed samples analyzed were found positive (concentration of clenbuterol ≥ 1 ppb). The results indicate that clenbuterol was misused in some of the areas surveyed.     

经济发展成本分析:可持续发展经济学的理论基础

可持续发展战略存在着理论与实践上的严重反差，其主要原因是可持续发展经济缺乏统一的理论基础，本文通过对经济学不同流派关于可持续发展问题研究的评析，认为可持续发展经济学需要建立一个统一的理论基础，并提出经济发展成本分析是可持续发展经济学的理论基础，围绕这一理论基础对可持续发展的概念进行了重新界定，并主张要把制度的激励与约束以及政策的引导纳入可持续发展经济途径研究的视野之中。     

以质量管理体系为基础建立实施一体化企业管理体系

结合镇海炼化实施一体化管理体系的实践,阐述了实施一体化体系的必要性和可行性,介绍了一体化管理体系的基本框架,以及体系建立和实施过程中的经验和体会.