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Animal venoms have aroused great interest during the past decades. During recent years, especially substances from marine animals have been investigated, not only in regard to their chemical structures but also to their biological relevance. Neurotoxic peptides from scorpions opened new aspects of action mechanisms on cell membranes; from snake venoms also ingredients have been obtained which serve as valuable pharmaceutical drugs. 相似文献
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Assessing the environmental fate of chemicals of emerging concern: a case study of the polybrominated diphenyl ethers 总被引:9,自引:0,他引:9
Palm A Cousins IT Mackay D Tysklind M Metcalfe C Alaee M 《Environmental pollution (Barking, Essex : 1987)》2002,117(2):195-213
It is suggested that assessments of chemicals of emerging concern can be rationally structured around a multistage process in which fate and risk are evaluated with increasing accuracy as new data become available. An initial tentative and approximate assessment of fate and risk can identify key data gaps and justify and direct further investigations, which progressively improve the reliability of the assessment. This approach is demonstrated for a class of chemicals, the polybrominated diphenyl ethers (PBDEs), which is of increasing concern, but about which there is presently a lack of comprehensive data on properties, sources, fate and effects. Specifically, 20 PBDE congeners are investigated using the suggested approach and research needs are identified. 相似文献
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Y. Collos C. Descolas-Gros M. Fontugne A. Mortain-Bertrand M. J. Chrétiennot-Dinet M. G. Frikha 《Marine Biology》1992,112(3):491-496
Under conditions of natural irradiance, the development and decline of a flagellate-dominated phytoplankton population was followed in a coastal North Atlantic pond over a 3 d period in summer 1986. Irradiance negatively affected phytoplankton biomass estimated as chlorophyll a, which decreased during the day at photosynthetically available radiation (PAR) levels above 600 to 1000 mol m-2s-1; chlorophyll a increased at PAR values below this threshold. In addition, an inverse relationship was found between changes in chlorophyll a and changes in dissolved inorganic nitrogen, indicating synthesis of nitrogenous biomass mainly at night and degradation mainly during the day, with intense exchanges of material between the particulate and dissolved nitrogen fractions. The natural abundance of 13C in particulate matter increased initially, and then remained constant, and was controlled mainly by the ratio -carboxylases activity: ribulose biphosphate carboxylase activity. The hypothesis that the latter enzyme is broken down under high irradiance and is partly responsible for increases in external dissolved nitrogen was rejected. 相似文献