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71.
The aim of the study was to investigate the antiproliferative properties of extracts of five plants on breast cancer cells (MDA-MB-231) and their effects on antioxidant activities. The total phenol contents of the extracts were determined to establish a correlation to their antiproliferative effects which were evaluated by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide viability assay. Enzymes involved in oxidative stress were also determined. Total polyphenol contents of the five extracts varied from 170 to 440 mg L?1 of gallic acid per mg of extract with the highest value for the extract of Sida cordifolia. Cell growth inhibition was observed within 24 h, with inhibitory concentration values ranging from 7.3 to 25 mg L?1 depending on plant extract. At concentrations between 100 and 200 mg L?1, all the extracts exhibited significant reduction of cell proliferation in time-dependent and linear manner. The activities of superoxide dismutase and catalase of cells treated for 24 h with the extract of S. cordifolia were 3.5 U per mg protein and 8 mole H2O2 consumed per min per mg protein higher than those of cells treated with an extract of Viscum album. 相似文献
72.
Woody encroachment decreases diversity across North American grasslands and savannas 总被引:2,自引:0,他引:2
Woody encroachment is a widespread and acute phenomenon affecting grasslands and savannas worldwide. We performed a meta-analysis of 29 studies from 13 different grassland/savanna communities in North America to determine the consequences of woody encroachment on plant species richness. In all 13 communities, species richness declined with woody plant encroachment (average decline = 45%). Species richness declined more in communities with higher precipitation (r2 = 0.81) and where encroachment was associated with a greater change in annual net primary productivity (ANPP; r2 = 0.69). Based on the strong positive correlation between precipitation and ANPP following encroachment (r2 = 0.87), we hypothesize that these relationships occur because water-limited woody plants experience a greater physiological and demographic release as precipitation increases. The observed relationship between species richness and ANPP provides support for the theoretical expectation that a trade-off occurs between richness and productivity in herbaceous communities. We conclude that woody plant encroachment leads to significant declines in species richness in North American grassland/savanna communities. 相似文献
73.
Yard EE Gilchrist J Haileyesus T Murphy M Collins C McIlvain N Comstock RD 《Journal of Safety Research》2010,41(6):471-474
Introduction
Heat illness is a leading cause of death and disability among U.S. high school athletes.Methods
To examine the incidence and characteristics of heat illness among high school athletes, CDC analyzed data from the National High School Sports-Related Injury Surveillance Study for the period 2005–2009.Results
During 2005–2009, the 100 schools sampled reported a total of 118 heat illnesses among high school athletes resulting in ≥ 1 day of time lost from athletic activity, a rate of 1.6 per 100,000 athlete-exposures, and an average of 29.5 time-loss heat illnesses per school year. The average corresponds to a weighted average annual estimate of 9,237 illnesses nationwide. The highest rate of time-loss heat illness was among football players, 4.5 per 100,000 athlete-exposures, a rate 10 times higher than the average rate (0.4) for the eight other sports. Time-loss heat illnesses occurred most frequently during August (66.3%) and while practicing or playing football (70.7%). No deaths were reported.Conclusions
Consistent with guidelines from the National Athletic Trainers’ Association, to reduce the risk for heat illness, high school athletic programs should implement heat-acclimatization guidelines (e.g., set limits on summer practice duration and intensity). All athletes, coaches, athletic trainers, and parents/guardians should be aware of the risk factors for heat illness, follow recommended strategies, and be prepared to respond quickly to symptoms of illness. Coaches also should continue to stress to their athletes the importance of maintaining proper hydration before, during, and after sports activities.Impact of industry
By implementing preventive recommendations and quickly recognizing and responding to heat illness, coaches, athletic trainers, and the sporting community can prevent future deaths. 相似文献74.
Agnew LJ Lyon S Gérard-Marchant P Collins VB Lembo AJ Steenhuis TS Walter MT 《Journal of environmental management》2006,78(1):63-76
Researchers have noted that current water quality protection strategies, like nutrient management plans, lack a sound hydrological underpinning for pollutant transport processes. This is especially true for areas like the northeastern U.S. where copious research has shown that variable source area hydrology largely governs runoff generation. The goal of this study was to develop a scientifically justified method to identify the locations that generate overland flow. Furthermore, this methodology must be computationally simple enough that it can be utilized or incorporated into nutrient management plans and other established water quality tools. We specifically tested the reliability of the 'distance from a stream,'D(s), and the 'topographic index,'lambda, to predict areas with a high propensity for generating overland flow, i.e. hydrologically sensitive areas (HSA). HSAs were defined by their probability of generating runoff, P(sat), based on 30 year simulations using a physically based hydrological model. Using GIS, each location's P(sat) was correlated with D(s) and lambda. We used three Delaware Co., NY watersheds in the New York City watershed system with areas varying in size from 1.6 to 37 km2 and with forested and agricultural land uses. The topographic index gave stronger, more regionally consistent correlations with P(sat) than did D(s). Equations correlating lambda and P(sat) for each month are presented and can be used to estimate hydrological sensitivity in the region surrounding our study watersheds, i.e. in Delaware Co. This work is currently being incorporated into an Internet Mapping System to facilitate user-friendly, on-line identification of HSAs. 相似文献
75.
Alan R. Collins Scott Steinback 《Journal of the American Water Resources Association》1993,29(2):199-209
ABSTRACT: About one-third of all West Virginians obtain domestic water from private water wells. In this research, mail and telephone surveys were used to investigate household responses to bacteria, mineral, and organic chemical contamination of domestic water supplies. Of households who were informed of contamination and acknowledged the problem, over 85 percent took action to avoid exposure to water contamination problems. The most common action was to clean and/or repair the water system (55.9 percent of valid surveys). Approximately 45 percent of households made investments of either a water treatment system, a new water source, or correction of contamination source. The average, annual economic cost of rural household actions was $320 for bacteria, $357 for minerals, and $1,090 for organic contamination. These economic costs represent a lower bound estimate for rural household willingness-to-pay (WTP) for a reduction in domestic water contamination from government action. On average, investment actions had lower annual economic costs than noninvestment actions of boiling and hauling water so that households who undertook investment actions in response to water contamination would have a lower WTP for government action to reduce water contamination. When effectiveness of water treatment systems was evaluated, treatment systems which require minimal household maintenance were found to reduce exposure to water contamination to safe levels as households intended when they installed the system. Treatment systems which were commonly ineffective included those which required continual maintenance (e.g., chiorinators) or were not designed to solve the contaminant problem for which they were purchased (e.g., filter systems for bacteria). 相似文献
76.
Tong Wu Charles Perrings Chenwei Shang James P. Collins Peter Daszak Ann Kinzig Ben A. Minteer 《Ambio》2020,49(4):939-949
Highly pathogenic avian influenza (HPAI) H5N1 has led to the death or destruction of millions of domesticated and wild birds and caused hundreds of human deaths worldwide. As with other HPAIs, H5N1 outbreaks among poultry have generally been caused by contact with infected migratory waterfowl at the interface of wildlands and human-dominated landscapes. Using a case–control epidemiological approach, we analyzed the relation between habitat protection and H5N1 outbreaks in China from 2004 to 2017. We found that while proximity to unprotected waterfowl habitats and rice paddy generally increased outbreak risk, proximity to the most highly protected habitats (e.g., Ramsar-designated lakes and wetlands) had the opposite effect. Protection likely involves two mechanisms: the separation of wild waterfowl and poultry populations and the diversion of wild waterfowl from human-dominated landscapes toward protected natural habitats. Wetland protection could therefore be an effective means to control avian influenza while also contributing to avian conservation. 相似文献
77.
William H. Armstrong Mathias J. Collins Noah P. Snyder 《Journal of the American Water Resources Association》2012,48(2):306-320
Armstrong, William H., Mathias J. Collins, and Noah P. Snyder, 2012. Increased Frequency of Low‐Magnitude Floods in New England. Journal of the American Water Resources Association (JAWRA) 48(2): 306‐320. DOI: 10.1111/j.1752‐1688.2011.00613.x Abstract: Recent studies document increasing precipitation and streamflow in the northeastern United States throughout the 20th and early 21st Centuries. Annual peak discharges have increased over this period on many New England rivers with dominantly natural streamflow – especially for smaller, more frequent floods. To better investigate high‐frequency floods (<5‐year recurrence interval), we analyze the partial duration flood series for 23 New England rivers selected for minimal human impact. The study rivers have continuous records through 2006 and an average period of record of 71 years. Twenty‐two of the 23 rivers show increasing trends in peaks over threshold per water year (POT/WY) – a direct measure of flood frequency – using the Mann‐Kendall trend test. Ten of these trends had p < 0.1. Seventeen rivers show positive trends in flood magnitude, six of which had p < 0.1. We also investigate a potential hydroclimatic shift in the region around 1970. Twenty‐two of the 23 rivers show increased POT/WY in the post‐1970 period when comparing pre‐ and post‐1970 records using the Wilcoxon rank‐sum test. More than half of these increases have p < 0.1, indicating a shift in flow regime toward more frequent flooding. Region wide, we found a median increase of one flood per year for the post‐1970 period. Because frequent floods are important channel‐forming flows, these results have implications for channel and floodplain morphology, aquatic habitat, and restoration. 相似文献
78.
Effects of biochar and the earthworm Eisenia fetida on the bioavailability of polycyclic aromatic hydrocarbons and potentially toxic elements 总被引:4,自引:0,他引:4
Gomez-Eyles JL Sizmur T Collins CD Hodson ME 《Environmental pollution (Barking, Essex : 1987)》2011,159(2):616-622
Polycyclic aromatic hydrocarbons (PAHs) and potentially toxic elements (PTEs) were monitored over 56 days in calcareous contaminated-soil amended with either or both biochar and Eisenia fetida. Biochar reduced total (449 to 306 mg kg−1) and bioavailable (cyclodextrin extractable) (276 to 182 mg kg−1) PAHs, PAH concentrations in E. fetida (up to 45%) but also earthworm weight. Earthworms increased PAH bioavailability by >40%. Combined treatment results were similar to the biochar-only treatment. Earthworms increased water soluble Co (3.4 to 29.2 mg kg−1), Cu (60.0 to 120.1 mg kg−1) and Ni (31.7 to 83.0 mg kg−1) but not As, Cd, Pb or Zn; biochar reduced water soluble Cu (60 to 37 mg kg−1). Combined treatment results were similar to the biochar-only treatment but gave a greater reduction in As and Cd mobility. Biochar has contaminated land remediation potential, but its long-term impact on contaminants and soil biota needs to be assessed. 相似文献
79.
Gomez-Eyles JL Collins CD Hodson ME 《Environmental pollution (Barking, Essex : 1987)》2011,159(4):918-923
Validating chemical methods to predict bioavailable fractions of polycyclic aromatic hydrocarbons (PAHs) by comparison with accumulation bioassays is problematic. Concentrations accumulated in soil organisms not only depend on the bioavailable fraction but also on contaminant properties. A historically contaminated soil was freshly spiked with deuterated PAHs (dPAHs). dPAHs have a similar fate to their respective undeuterated analogues, so chemical methods that give good indications of bioavailability should extract the fresh more readily available dPAHs and historic more recalcitrant PAHs in similar proportions to those in which they are accumulated in the tissues of test organisms. Cyclodextrin and butanol extractions predicted the bioavailable fraction for earthworms (Eisenia fetida) and plants (Lolium multiflorum) better than the exhaustive extraction. The PAHs accumulated by earthworms had a larger dPAH:PAH ratio than that predicted by chemical methods. The isotope ratio method described here provides an effective way of evaluating other chemical methods to predict bioavailability. 相似文献
80.
John H. Martin Alan R. Collins Robert G. Diener P.E. 《Journal of the Air & Waste Management Association (1995)》2013,63(11):864-870
Abstract This article reports on development of a protocol for characterizing municipal solid waste (MSW). This protocol is similar to that recommended by the American Society for Testing and Materials but includes a distinction between pure and mixed loads of MSW. Thirteen component categories were used with a focus on material feed stock for composting, recycling, and reuse. The required number of samples was determined to achieve a 80%, 90%, and 95% statistical accuracy for characterizing MSW categories at 1% and 2% sampling error. This study found that a maximum of 25 randomly collected samples of 200 pounds will reflect each component category of mixed load MSW with at least a 95% confidence level and 2% error. This protocol was successfully tested in Monongalia County, West Virginia, to provide a “snapshot” MSW characterization during early summer. 相似文献