Sonographically determined anomalies and outcome in 170 chromosomally abnormal fetuses

Structural pathology and outcome were studied in 170 chromosomally abnormal fetuses. Numerical chromosomal abnormalities were established in 158 (93 per cent) cases, of which 110 (71 per cent) represented trisomies, 30 (18 per cent) Turner syndrome, and 18 (11 per cent) triploidy. Structural chromosomal abnormalities were diagnosed in 12 (7 per cent) cases. Gestational age at referral was significantly shorter for pregnancies with Turner syndrome than for the other chromosomal abnormalities. Referral before 20 weeks of gestation was mainly based on fetal structural pathology alone (92 per cent); after 20 weeks, patients were referred because of structural pathology combined with small for gestational age, oligohydramnios, or polyhydramnios. Referral as a result of suspected multiple organ pathology occurred in 73.5 per cent of pregnancies. An abnormal amniotic fluid volume was present in 59/170 (34.5 per cent) chromosomally affected pregnancies, i.e., oligohydramnios in 31 and polyhydramnios in 28 cases. Birth weight was below the tenth percentile in over half of the chromosomally abnormal fetuses, except for Turnersyndrome. Fetal outcome was poor, with a survival rate at 1 month of 30 per cent for trisomies which was mainly determined by trisomy 21 (14/18=77.5 per cent).     

The citrus pyslla, Trioza erytreae (Del Guercio) (hemiptera: Triozidae): A review

The literature on the citrus psylla, Trioza erytreae, published since 1897, is reviewed. The citrus psylla is an important vector of the greening disease of citrus. The stages of development and life history are discussed. Of the factors that influence population size, flushing of the host plants and high saturation deficits are the most important. Methods of population monitoring and control are summarised. The main means of reducing vector numbers and therefore the spread of greening disease, are resistance of citrus trees to greening disease, restricting citrus growing to hot, low-lying regions of the country, and strict vector control in nurseries. Requirements for further research, are discussed.     

Effects of cross-substrate interaction on biotrickling filtration for the control of VOC emissions

The effects of cross-substrate interaction to the performance of a gas-phase biotrickling filter for treating a mixture of volatile organic compounds (VOCs), including three structural heterologous in acetone, toluene, and trichloroethylene, were investigated. The biotrickling filter was inoculated with microbial consortium containing at least seven bacterial species utilizing either acetone or toluene, or both, as their carbon sources. In the performance study, the column operating under variable conditions typifying the waste gas emission from the microelectronics fabrication processes achieved a total hydrocarbon (THC) removal efficiency in excess of 85% and a mineralization capacity over 50% for THC mass loading as high as 36.2 g-CH4 m-3h-1. The cross-substrate effects were examined by correlating the relative changes in the mass removal of each substrate with the biodegradative capability of the microbial consortium. The degradation of trichloroethylene was primarily due to co-metabolism by the toluene-oxidizing enzymes, but the results also indicated that trichloroethylene partially induced its own degradation. Concentration increases in acetone appeared to cause a diauxie effect that suppressed degradation of toluene and trichloroethylene, and shifted the microbial population toward the selective acetone-degraders. No irrecoverable toxicity or inhibitory effects were observed throughout the experiments. These results suggest that the relative VOC concentration in the waste gas mixture is a factor as important as the biodegradative function of the microbial consortium, and thus should be carefully evaluated to satisfy the treatment objectives.     

The Precautionary Principle and Pesticides

In 1998, Greenpeace, Natuur en Milieu(Nature and Environment), Milieudefensie(Environmental Defense), and the National ConsumersUnion presented a report about the possible risks andhazards associated with pesticide residues on fruitsand vegetables. Although these organizationsexplicitly denied having unassailable evidence on theharmful effects of pesticides, they claimed that bynow there are sufficient indications that pesticidesmay indeed lead to such health hazards. They used anappeal to the so-called precautionary principle tounderpin their claims. The committee officially incharge of deciding on the admission of pesticidesaccused the organizations of scaremongering. Afterdistinguishing three possible versions of theprecautionary principle, we then show that the fourorganizations used in their campaign an improperversion of the precautionary principle to convince thegeneral public.     

MTBE与雌二醇对螺旋鱼腥藻的联合毒性

以螺旋鱼腥藻(Anabaena spiroides)为实验材料,采用每天测定数据,连续跟踪10d的方法,研究了甲基叔丁基醚(Methyl tert-buty1 ether,MTBE)与雌二醇对螺旋鱼腥藻的单一毒性以及在不同毒性单位配比下的联合毒性,选用毒性单位(TU)、相加指数(AI)、混合毒性指数(MTI)和毒性增大指数(TEI)进行联合毒性评价.结果表明,MTBE与雌二醇共存时,在实验周期(10d)内,其联合作用方式基本表现为协同作用.此外,MTBE和雌二醇的单一毒性和联合毒性数据随着培养时间的变化而产生剧烈变化,毒性数据在培养时间3～7d比较平稳,在4～5d最佳.     

First assessment of population exposure to perfluorinated compounds in Flanders, Belgium

With the objective to evaluate exposure of the population in Flanders (Belgium) to perfluorinated compounds (PFCs), we measured perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) in settled dust in homes and offices, in a selection of food items from local origin, in drinking-water and in human serum. We complemented the data with results from a literature survey. Based on this dataset we calculated intake by children and adults from food, drinking-water, settled dust and soil, and air. Dietary exposure dominated overall intake. For adults, average dietary intake equalled 24.2 (P95 40.9) ng PFOS kg⁻¹ d⁻¹ and 6.1 (P95 9.6) ng PFOA kg⁻¹ d⁻¹, whereas for children the dietary intake was about 3 times higher. Predicted intake is high when compared to assessments in other countries, and to serum levels from Flanders, but comparable to the intakes published by The European Food Safety Authority (EFSA) in 2008. Intake of PFOS and PFOA remained below the Tolerable Daily Intake.     

Climate adaptation in fragmented governance settings: the consequences of reform in public administration

The impact of dominant trends in public administration, such as decentralisation and privatisation on complex collective challenges is insufficiently understood. This is relevant in settings where climate change impacts become manifest at local level, and where financing power resides at national level but decisions are made more locally in a fragmented institutional setting. This study assists in overcoming this gap by analysing how the institutional context (i.e. a decentralised, privatised, fragmented setting) influences the capacity to address climate change challenges in a vulnerable area (the South Devon coast in the UK). There has been little action to address expected climate change impacts in this vulnerable stretch of coast. A lack of clarity around responsibility for addressing climate impacts and a lack of a deliberative structure between various actors involved, within a context of austerity, hamper climate change adaptation. The findings question whether decentralised decision making is sufficient for addressing climate adaptation challenges.     

Do wood mice (Apodemus sylvaticus L.) use food selection as a means to reduce heavy metal intake?

Food preference of wood mice from two with heavy metals polluted sites and two unpolluted sites was tested under laboratory and field conditions with two-way choice experiments. In the laboratory, wood mice preferred to eat acorns from unpolluted sites over acorns from polluted sites. Previous experience with polluted food had no influence on food choice. Preference was negatively related to acorn metal content. Furthermore, the nutrient content of the acorn endosperm was consistently lower in polluted sites. We therefore conclude that wood mice used absolute metal concentration in the acorn, nutrient content, or both as a food selection cue. The results of the laboratory experiment could not be confirmed under field conditions. We hypothesized that search time constraints due to the presence of predators, competitors and/or other stress factors in the field have prevented the mice to forage selectively.     

Dietary exposure to dioxin-like compounds in three age groups: results from the Flemish environment and health study

Lipophilic contaminants are present in the environment and bioaccumulate in the food chain. Therefore, their intake via animal fat of various sources was assessed for three age groups of the Flemish population, participating in a large biomonitoring program of the Flemish government. In total, 1636 adolescents (14-15 years), 1186 mothers (18-44 years), and 1586 adults (50-65 years) participated in the study and completed a semi quantitative food frequency questionnaire. Individual consumption data were combined, via a so-called simple distribution approach, with recent data on polychlorinated dibenzo-p-dioxins/furans and dioxin-like polychlorinated biphenyls, measured via the chemical-activated luciferase gene expression (CALUX) bio-assay in food items available on the Flemish market. The median (95th percentile) estimated intakes of dioxin-like contaminants were 2.24 (4.61), 2.09 (4.26), and 1.74 (3.53) pg CALUX-TEQ kg(-1) bw d(-1) for, respectively adolescents, mothers and adults. These data are in the same range as those found in other European studies. The CALUX-TEQ results of respectively 59.8%, 53.7% and 36.2% of the adolescent, mother and adult population exceed the tolerable weekly intake (TWI) of 14 pg WHO-TEQ kg(-1) bw w(-1), as derived by the Scientific Committee on Food [Scientific Committee on Food, 2001. Opinion of the Scientific Committee on Food on the Risk Assessment of Dioxins and Dioxin-like PCBs in Food, CS/CNTM/DIOXIN/20 final Brussels, Belgium]. The main contributors of dioxin-like substances are fish and seafood (25-43% of the total intake), added fats (22-25% of the total intake) and dairy products (17-20% of the total intake).