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62.
Dietary exposure to dioxin-like compounds in three age groups: results from the Flemish environment and health study 总被引:2,自引:0,他引:2
Bilau M Matthys C Baeyens W Bruckers L De Backer G Den Hond E Keune H Koppen G Nelen V Schoeters G Van Larebeke N Willems JL De Henauw S;Flemish Center of Expertise for Environment Health 《Chemosphere》2008,70(4):584-592
Lipophilic contaminants are present in the environment and bioaccumulate in the food chain. Therefore, their intake via animal fat of various sources was assessed for three age groups of the Flemish population, participating in a large biomonitoring program of the Flemish government. In total, 1636 adolescents (14-15 years), 1186 mothers (18-44 years), and 1586 adults (50-65 years) participated in the study and completed a semi quantitative food frequency questionnaire. Individual consumption data were combined, via a so-called simple distribution approach, with recent data on polychlorinated dibenzo-p-dioxins/furans and dioxin-like polychlorinated biphenyls, measured via the chemical-activated luciferase gene expression (CALUX) bio-assay in food items available on the Flemish market. The median (95th percentile) estimated intakes of dioxin-like contaminants were 2.24 (4.61), 2.09 (4.26), and 1.74 (3.53) pg CALUX-TEQ kg(-1) bw d(-1) for, respectively adolescents, mothers and adults. These data are in the same range as those found in other European studies. The CALUX-TEQ results of respectively 59.8%, 53.7% and 36.2% of the adolescent, mother and adult population exceed the tolerable weekly intake (TWI) of 14 pg WHO-TEQ kg(-1) bw w(-1), as derived by the Scientific Committee on Food [Scientific Committee on Food, 2001. Opinion of the Scientific Committee on Food on the Risk Assessment of Dioxins and Dioxin-like PCBs in Food, CS/CNTM/DIOXIN/20 final Brussels, Belgium]. The main contributors of dioxin-like substances are fish and seafood (25-43% of the total intake), added fats (22-25% of the total intake) and dairy products (17-20% of the total intake). 相似文献
63.
Sander Van Den Burg 《Local Environment》2004,9(4):367-381
This paper studies the emergence of one particular 'new' environmental policy instrument: disclosure of emission and pollution data. Disclosure is part of a relatively new sub-set of regulatory measures, based on monitoring, transparency, citizen-empowerment and accountability. It originated in the United States but has recently attracted international attention. The attractiveness of disclosure is obvious; it promises environmental improvement combined with strengthened environmental democracy and community empowerment. By analysing the experiences in the US, and the developments in the Netherlands, this paper seeks to assess the functioning and effectiveness of disclosure. The available empirical evidence suggests that disclosure has a positive impact on the environmental performance of industrial facilities as well as a democratising effect. It is argued that Dutch policy makers wrongfully assume that disclosure cannot work in the Netherlands. The consequence is that citizens are provided with little specific information that cannot be used to put pressure on polluters. 相似文献
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Diane Van Opstal Jan O. Van Hemel Bert H. J. Eussen Annet Van Der Heide Cardi Van Den Berg Peter A. In't Veld Frans J. Los 《黑龙江环境通报》1995,15(8):705-711
Fluorescent in situ hybridization (FISH) with a 21q11-specific probe (CB21c1) consisting of three non-overlapping cosmids has been applied to interphase amniocytes of pregnancies at increased risk for fetal aneuploidy (N = 78) and to interphase lymphocytes, cultured and uncultured, of patients referred for Down syndrome (N = 19 and 28, respectively). In the uncultured amniocytes, six chromosome aberrations were detected: three cases of trisomy 21, a triploidy, a de novo 46,XX,t(21q21q), and a mosaic 46,XY/47,XY,+dic(21)(q11)/48,XY,+dic(21)(q11), +del(21)(q11). In 15 cultured and 20 uncultured blood samples, FISH correctly diagnosed trisomy 21 (full or mosaic) at the interphase level, which was confirmed in all cases by subsequent karyotyping. Because of specific and strong signals in interphase nuclei, CB21c1 appears to be a useful tool for the rapid detection of chromosome 21 abnormalities. 相似文献
67.
提出了用气相色谱直接测定水、土、粮食水果和蔬菜中10种有机氮农药多残留的分析方法.样品采用丙酮振荡或组织捣碎提取,二氯甲烷萃取,经凝结或柱层析法净化.使用Sigma2型带NPD的气谱仪测定.气谱柱长1m,内径0.2cm,填充5%OV-17/Gas Chrom Q(80—100目),该柱在恒温的色谱条件下能将10种有机氮农药完全分离.通过方法回收率及八种类型样品的添加回收率证实方法的可靠及可行性,共添加回收率为81.76—102.03%,变异系数0.52—10.33%,最低检测浓度为0.0004—0.0218ppm. 相似文献