全文获取类型
收费全文 | 1045篇 |
免费 | 1篇 |
专业分类
安全科学 | 18篇 |
废物处理 | 2篇 |
环保管理 | 86篇 |
综合类 | 824篇 |
基础理论 | 67篇 |
污染及防治 | 36篇 |
评价与监测 | 8篇 |
社会与环境 | 2篇 |
灾害及防治 | 3篇 |
出版年
2021年 | 4篇 |
2018年 | 5篇 |
2017年 | 4篇 |
2016年 | 5篇 |
2015年 | 7篇 |
2014年 | 10篇 |
2013年 | 39篇 |
2012年 | 6篇 |
2010年 | 12篇 |
2009年 | 5篇 |
2008年 | 10篇 |
2007年 | 6篇 |
2005年 | 5篇 |
2004年 | 5篇 |
2003年 | 12篇 |
2002年 | 10篇 |
1999年 | 4篇 |
1998年 | 12篇 |
1997年 | 4篇 |
1995年 | 56篇 |
1994年 | 50篇 |
1993年 | 38篇 |
1992年 | 32篇 |
1991年 | 26篇 |
1990年 | 32篇 |
1989年 | 25篇 |
1988年 | 35篇 |
1987年 | 29篇 |
1986年 | 21篇 |
1985年 | 14篇 |
1984年 | 12篇 |
1983年 | 14篇 |
1982年 | 10篇 |
1981年 | 4篇 |
1979年 | 5篇 |
1976年 | 6篇 |
1975年 | 9篇 |
1974年 | 4篇 |
1973年 | 10篇 |
1971年 | 4篇 |
1962年 | 3篇 |
1961年 | 4篇 |
1950年 | 3篇 |
1919年 | 47篇 |
1918年 | 44篇 |
1917年 | 36篇 |
1916年 | 54篇 |
1915年 | 37篇 |
1914年 | 71篇 |
1913年 | 107篇 |
排序方式: 共有1046条查询结果,搜索用时 15 毫秒
401.
Dr. Mitchell S. Golbus Thomas J. Simpson Mitsuhiko Koresawa Zvi Appelman Charles E. Alpers 《黑龙江环境通报》1988,8(6):401-404
Two fetuses at risk for glucose-6-phosphatase deficiency had in utero liver biopsies. Analysis of each showed this enzyme activity to be in the normal range and the pregnancies continued. Neither child has any clinical or metabolic evidence of glucose-6-phosphatase deficiency. 相似文献
402.
Dr Joyce C. Harper Edith Coonen Alan H. Handyside Robert M. L. Winston Anton H. N. Hopman Joy D. A. Delhanty 《黑龙江环境通报》1995,15(1):41-49
We have previously detected chromosome abnormalities in human embryos whilst identifying the sex for preimplantation diagnosis of X-linked disease. In this study we assess the incidence of these abnormalities, both for sex chromosomes and autosomes 1 and 17, using dual fluorescent in situ hybridization (FISH). Sixty-nine normally fertilized embryos of good morphology at the 6–10 cell stage (day 3 post-insemination) were examined. The embryos were spread whole using HCl and Tween 20 to dissolve the cytoplasm. Thirty-four embryos were analysed for the sex chromosomes and 35 for autosomes 1 and 17. All probes were directly labelled with fluorochromes allowing analysis in 2 h. Control lymphocytes demonstrated that the probes were of high specificity. For the sex chromosomes, five embryos were mosaic (15 per cent) with the remaining 29 being uniformly XX or XY. In no case was an XX nucleus found in an otherwise XY embryo, indicating that even though mosaicism for the sex chromosomes is present, such abnormalities would not lead to a misdiagnosis of sex. For the autosomes, 16 embryos were abnormal (46 per cent); one embryo was triploid, one was monosomic for chromosome 1, and ten others were diploid mosaics (three diploid/aneuploid, three diploid/polyploid, and four diploid/haploid). A further four embryos had variable chromosome numbers in the majority of nuclei which appeared to be the result of uncontrolled mitotic division. The presence of haploidy or double monosomy, which occurred in 15 per cent of nuclei, has important implications for the diagnosis of trisomies and dominant disorders. 相似文献
403.
Fetomaternal haemorrhage (FMH) was studied after 46 cordocenteses. α-Fetoprotein (AFP) concentration and Kleihauer staining of maternal blood, taken both before and after the procedure, revealed increases in AFP values of more than 40 per cent in 30 per cent of the patients examined; fetal haemorrhage of more than 0.25 ml was detected in 46 per cent of the cases by the Kleihauer test. In the second trimester of pregnancy both techniques are comparable, while in the third trimester the Kleihauer technique appears to be more sensitive in detecting FMH after cordocentesis. An anterior position of the placenta is a risk factor for FMH. 相似文献
404.
Dr. Jane L. Halliday Lyndsey F. Watson Judith Lumley David M. Danks Leslie J. Sheffield 《黑龙江环境通报》1995,15(5):455-465
Current measures of livebirth prevalence of Down syndrome are derived from data obtained up to 20 years ago, before the introduction of the prenatal diagnostic tests amniocentesis and chorionic villus sampling (CVS). For women aged 36–52 years, but who were not tested prenatally, we proposed to make a direct estimate of current livebirth prevalence of Down syndrome. We could also determine prevalence at the time of CVS and amniocentesis in women of the same age undergoing prenatal testing. Differences in these prevalences allow an estimation of the relative loss of Down syndrome during pregnancy. In Victoria, Australia, we identified 3041 women having CVS, 7504 having amniocentesis, and 13 139 having no test. Smoothed regression estimates of age-specific livebirth prevalence were found to be higher than in the early studies. The estimate of spontaneous loss was 17 per cent between the time of CVS and amniocentesis, and 18 per cent after the time of amniocentesis. The latter figure is lower than previous estimates and may be explained by a greater likelihood of a Down syndrome fetus surviving to be liveborn, given the modern approach to early obstetric intervention. These current risk estimates of livebirth may be useful updates for genetic counselling, but perhaps more importantly, may be used as precise maternal age-related risk figures, necessary in the design and implementation of prenatal screening programmes for Down syndrome. 相似文献
405.
Jon Barret Dr David Chitayat MD FABMG FCCMG Matthew Sermer Koffi Amankwah Robert Morrow Ants Toi Greg Ryan 《黑龙江环境通报》1995,15(9):849-853
The prenatal diagnosis of an echogenic fetal lung (EFL) is now often made in the early second trimester using high-resolution ultrasound. This ultrasound appearance is usually caused by a congenital cystic adenomatoid lung malformation (CCAM), an intrapulmonary lung sequestration or obstruction of a major airway. In order to provide prognostic guidelines to parents who may be considering termination of a fetus with these findings, we have analysed a series of 11 cases diagnosed in our centre over the past 2 years in conjunction with 60 cases from major published series. The data suggest that in the absence of non-immune hydrops fetalis (NIHF) or other anomalies, the outcome for the fetuses is excellent, with over 90 per cent survival. Neither early diagnosis (24 weeks) nor the presence of mediastinal shift is a poor prognostic indicator. In addition, it appears that if NIHF is absent at diagnosis, the chance that it will develop as the pregnancy continues is small (6 per cent). Furthermore, there is a significant (up to 30 per cent) chance that this ultrasound finding will resolve in utero. The development of in utero fetal surgical techniques may be the only hope for those hydropic fetuses who appear to have a dismal prognosis. 相似文献
406.
Dr Antonio Perez-Aytes Nuria Sanchis Agnes Barbal Maria Jose Artés Julio Domene Melitina Chirivella Andres Baamonde 《黑龙江环境通报》1995,15(9):859-863
A large intrapericardial teratoma was found at necropsy in a 38−week stillborn fetus, in which prenatal diagnosis of hydrops fetalis and an ehogenic cardiac mass had been made. Clinical and pathological data are reported. In utero intrapericardial teratomata lead to different outcomes depending on whether fetal hydrops is associated. When generalized fetal hydrops is not present, the outcome is good, even in cases with large pericardial effusions. When generalized fetal hydrops occurs, it often results in a poor outcome. In our literature review, we have found eight perinatal deaths in nine similar cases reported. 相似文献
407.
Dr Boris Tutschek Jon Sherlock Ashutosh Halder Joy Delhanty Charles Rodeck Matteo Adinolfi 《黑龙江环境通报》1995,15(10):951-960
Transcervical cell (TCC) samples have been shown to contain fetal cells amenable to molecular analysis. However, the presence of ‘contaminating’ maternal cells limits their use for prenatal diagnoses. In this report we show that clumps of fetal cells can be isolated from transcervical samples by micromanipulation and tested by fluorescence in situ hybridization (FISH) and polymerase chain reaction (PCR). Out of 129 clumps, isolated from mucus aspirates and transcervical lavages from 29 patients, 29 clumps from 11 patients were found to be exclusively of fetal origin as judged by the detection of chromosome 21-specific polymorphic DNA markers and Y-derived DNA sequences by PCR and FISH. One case of a male triploid fetus, diagnosed by the analysis of TCC samples obtained by mucus aspiration and lavage, was confirmed by testing clumps of cells isolated by micromanipulation. 相似文献
408.
409.
Chorionic villus sampling (CVS) was performed in 12 pregnant women (9–25 gestational weeks) with ultrasonographic evidence of missed abortion. An ultrasonographically guided transabdominal (eight cases) or transcervical (four cases) approach was used. Fetal karyo-typing was successful in all cases; in five, chromosomal aberrations were found and in seven, chromosome analyses revealed normal karyotypes. Tissue culture for fetal karyotyping was successful in only 72.5 per cent of 40 live pregnancies which were electively interrupted because of abnormal ultrasonographic findings or an abnormal fetal karyotype, and in 57 per cent of seven missed abortions. CVS is suggested as a feasible and effective method for fetal karyotyping in missed abortions and it seems to be superior to post-abortion tissue culture. 相似文献
410.
A case of true fetal mosaicism 46,XY/47,XY, + 17 was diagnosed in amniotic fluid cells. After genetic counselling and unsuccessful periumbilical blood sampling the pregnancy continued to term, and a healthy male infant was born. Lymphocytes of the newborn had a normal karyotype. Follow-up of the child at age 18 months showed normal physical and mental development indicating that the trisomic cell line was restricted most probably to the extra fetal tissue. 相似文献