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231.
Lena Wartosch Karen Schindler Melina Schuh Jennifer R. Gruhn Eva R. Hoffmann Rajiv C. McCoy Jinchuan Xing 《黑龙江环境通报》2021,41(5):620-630
The gain or loss of a chromosome—or aneuploidy—acts as one of the major triggers for infertility and pregnancy loss in humans. These chromosomal abnormalities affect more than 40% of eggs in women at both ends of the age spectrum, that is, young girls as well as women of advancing maternal age. Recent studies in human oocytes and embryos using genomics, cytogenetics, and in silico modeling all provide new insight into the rates and potential genetic and cellular factors associated with aneuploidy at varying stages of development. Here, we review recent studies that are shedding light on potential molecular mechanisms of chromosome missegregation in oocytes and embryos across the entire female reproductive life span. 相似文献
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Reyer Christopher P.O Otto Ilona M. Adams Sophie Albrecht Torsten Baarsch Florent Cartsburg Matti Coumou Dim Eden Alexander Ludi Eva Marcus Rachel Mengel Matthias Mosello Beatrice Robinson Alexander Schleussner Carl-Friedrich Serdeczny Olivia Stagl Judith 《Regional Environmental Change》2017,17(6):1639-1650
Regional Environmental Change - This paper synthesizes what is known about the physical and biophysical impacts of climate change and their consequences for societies and development under... 相似文献
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Stano Pekár Onřej Šedo Eva Líznarová Stanislav Korenko Zdeněk Zdráhal 《Die Naturwissenschaften》2014,101(7):533-540
It is rare to find a true predator that repeatedly and routinely kills prey larger than itself. A solitary specialised ant-eating spider of the genus Zodarion can capture a relatively giant prey. We studied the trophic niche of this spider species and investigated its adaptations (behavioural and venomic) that are used to capture ants. We found that the spider captures mainly polymorphic Messor arenarius ants. Adult female spiders captured large morphs while tiny juveniles captured smaller morphs, yet in both cases ants were giant in comparison with spider size. All specimens used an effective prey capture strategy that protected them from ant retaliation. Juvenile and adult spiders were able to paralyse their prey using a single bite. The venom glands of adults were more than 50 times larger than those of juvenile spiders, but the paralysis latency of juveniles was 1.5 times longer. This suggests that this spider species possesses very potent venom already at the juvenile stage. Comparison of the venom composition between juvenile and adult spiders did not reveal significant differences. We discovered here that specialised capture combined with very effective venom enables the capture of giant prey. 相似文献
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