Prenatal morphology in meckel's syndrome (with special reference to polycystic kidneys and double encephalocele)

Prenatal morphology of Meckel's syndrome was studied in five fetuses of different gestational age, that had been aborted because ultrasonography and elevated amniotic AFP-levels indicated neural tube defect. Histologically, the enlarged polycystic kidneys were completely alike with respect to the type of involvement and differed only in the severity of changes. They could be identified as type III cystic kidneys according to the classification of Potter. Proliferation of hepatic bile ducts and slight cystic dilatation of pancreatic ducts is already evident in the youngest fetus. Additional cyst formation in the epididymis was found in one of the cases. Occipital encephalocele, located within an apical occipital bone defect was always associated with a second mostly occult encephalocele protruding through a separate defect of the basal occipital squame and of the first and second vertebral arch. It is assumed that double encephalocele represents a constant finding in Meckel's syndrome, indicating a specific pattern within the disturbance of neural tube closure.     

Environmental Cleanliness as a Public Good: Welfare and Policy Implications of Nonconvex Preferences

This paper explores the implications of a form of nonconvexity in individual preferences over the public good “cleanliness.” The implications of this nonconvexity on equilibrium outcomes, welfare analysis, the process of development, and optimal government policy are examined. The nonconvexity can imply a role for government in providing a commitment to a clean environment even if the government has a cost disadvantage in cleaning compared with individuals. By providing a credible commitment to a clean environment the government can induce private individuals to undertake optimal levels of cleaning on their own.