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71.
The comparison of increasing doses of a treatment to a negative control is frequently part of toxicological studies. For normally distributed data Williams (1971, 1972) introduced a maximum likelihood test under total order restriction. But until now there seems to have been no solution for the arbitrary unbalanced case. According to the idea proposed by Robertson et al. (1988) we will apply in this article the basic concept of Williams on the class of multiple contrast tests for the general unbalanced parametric set-up. Simulation results for size and power and two examples for estimating the minimal toxic dose (MTD) are given. 相似文献
72.
Peter H. Roos Walter D. Weißenfels Manfred van Afferden Frank Pfeifer Walter G. Hanstein 《Environmental Sciences Europe》2000,12(1):13-19
The goal of the present work is to assess the adverse effects of soil bound polycyclic aromatic hydrocarbons (PAH) which remain in soils after biological remediation. We focus on risk assessment for mammalian species with respect to the oral uptake of contaminated soil particles and compare the results of a biomarker test with those of an ecotoxicological assay, the bioluminescence inhibition test withVibrio fischeri. As a biomarker effect in mammals, we determined the liver microsomal cytochrome P450 enzyme CYP1A1 which is induced by PAH in exposed rats. After biological soil treatment, different amounts of PAH remain in the soil depending on the soil properties and initial pollutant composition. Particularly, higher condensated PAH resists biological treatment due to its hydrophobicity. In addition, high amounts of organic carbon in the soils affect remediation efficiency. In the bioluminescence inhibition test, eluates of all biologically treated soils studied do not reveal any or only low inhibitory effects. In contrast, the oral uptake of biologically treated contaminated soils leads to induction levels for CYP1A1 similar to those in the untreated samples. A good correlation is obtained between CYP1A1 levels and the amount of 5 and 6-ring PAH in the soil samples. The main result is that the remediation efficiency determined by the luminescence test is not reflected by the biomarker test, a finding which indicates the high bioavailability of residual PAH in soils. Consequently, new criteria for human risk assessment can be delineated. 相似文献
73.
74.
N. Sallem-Idrissi P. Van Velthem M. Sclavons 《Journal of Polymers and the Environment》2018,26(12):4405-4414
Ecofriendly fully bio-composites based on polyamide 11 (PA11) and lignin have been prepared on the entire concentration range using a twin-screw extruder. In this work, PA11 was blended with lignin by direct extrusion technology without any chemical pre- or in-situ- modifications or physical pretreatments. The presence of various organic and inorganic impurities in the selected technical lignin have been maintained. The incorporation of this cheap renewable material from biomass in bio-based PA11 was inspected by an array of characterization tools. Also, the effect of the presence of lignin on the morphology and on the mechanical properties of the resulting materials was examined. Finally, in-situ investigation of structural evolution in PA11 induced by the presence of lignin was analyzed by Fast Scanning Chip Calorimetry. 相似文献
75.
Ivar Lyhne Matthew Cashmore Hens Runhaar Frank van Laerhoven 《Journal of Environmental Policy & Planning》2016,18(1):121-140
The spectre of regulatory reform carried out in a range of Western countries has generated concern amongst parts of the environmental policy community. Quality and effectiveness are said to be at stake, but empirically there is a dearth of data on the relationship between provisions for quality control and the effects on quality and effectiveness. This research addresses this lacuna by analysing the effects of different quality control provisions in the Netherlands and Denmark for a globally institutionalized environmental appraisal tool—Environmental Assessment (EA). Extensive technical provisions for quality control in the Netherlands have led to it being described as the ‘Rolls Royce’ of EA systems, while in Denmark the polity is expected to take charge of quality control. The effects of quality control are investigated through surveys and in-depth interviews with actors centrally engaged with EA implementation. The results show that quality control provisions are poorly related to the perceived quality and effectiveness of EA. Only the appropriateness of the scope of EA reports is perceived to be strongly related to quality control provisions. The findings are relevant for environmental policy communities concerned with quality control systems and effectiveness of policy appraisal tools and policy-makers contemplating regulatory reforms. 相似文献
76.
David A. Ross Héctor M. Guzmán Vincent J. Van Hinsberg Catherine Potvin 《Journal of environmental science and health. Part. B》2016,51(10):675-687
Concentrations of eight elements were measured in Chelonia mydas and Lepidochelys olivacea eggs collected along the Pacific coast of Panama. Manganese (Mn), iron (Fe), copper (Cu), zinc (Zn), arsenic (As), cadmium (Cd), and mercury (Hg) concentrations were similar to previous reports of these species from around the world, while lead (Pb) was lower than previous reports. Cd posed the highest health risk to people who regularly eat the eggs, with average consumption rates leading to target hazard quotients (THQ) of up to 0.35 ± 0.15. Our conclusions indicate that current turtle egg consumption in isolated, coastal Pacific communities may pose a health concern for young children, and that youth and young adults should limit their consumption of turtle eggs to reduce their total intake of nonessential metals. 相似文献
77.
78.
Dries Verheyen Nele Van Gaelen Benedicta Ronchi Okke Batelaan Eric Struyf Gerard Govers Roel Merckx Jan Diels 《Ambio》2015,44(2):228-240
Diffuse phosphorus (P) export from agricultural land to surface waters is a significant environmental problem. It is critical to determine the natural background P losses from diffuse sources, but their identification and quantification is difficult. In this study, three headwater catchments with differing land use (arable, pasture and forest) were monitored for 3 years to quantify exports of dissolved (<0.45 µm) reactive P and total dissolved P. Mean total P exports from the arable catchment ranged between 0.08 and 0.28 kg ha?1 year?1. Compared with the reference condition (forest), arable land and pasture exported up to 11-fold more dissolved P. The contribution of dissolved (<0.45 µm) unreactive P was low to negligible in every catchment. Agricultural practices can exert large pressures on surface waters that are controlled by hydrological factors. Adapting policy to cope with these factors is needed for lowering these pressures in the future. 相似文献
79.
The regional-scale importance of an aquatic stressor depends both on its regional extent (i.e., how widespread it is) and
on the severity of its effects in ecosystems where it is found. Sample surveys, such as those developed by the U.S. Environmental
Protection Agency’s Environmental Monitoring and Assessment Program (EMAP), are designed to estimate and compare the extents,
throughout a large region, of elevated conditions for various aquatic stressors. In this article, we propose relative risk
as a complementary measure of the severity of each stressor’s effect on a response variable that characterizes aquatic ecological
condition. Specifically, relative risk measures the strength of association between stressor and response variables that can
be classified as either “good” (i.e., reference) or “poor” (i.e., different from reference). We present formulae for estimating
relative risk and its confidence interval, adapted for the unequal sample inclusion probabilities employed in EMAP surveys.
For a recent EMAP survey of streams in five Mid-Atlantic states, we estimated the relative extents of eight stressors as well
as their relative risks to aquatic macroinvertebrate assemblages, with assemblage condition measured by an index of biotic
integrity (IBI). For example, a measure of excess sedimentation had a relative risk of 1.60 for macroinvertebrate IBI, with
the meaning that poor IBI conditions were 1.6 times more likely to be found in streams having poor conditions of sedimentation
than in streams having good sedimentation conditions. We show how stressor extent and relative risk estimates, viewed together,
offer a compact and comprehensive assessment of the relative importances of multiple stressors. 相似文献
80.
Cuong Van Hoang Tuyen Quang Tran Yen Hai Thi Nguyen Lan Thanh Nguyen 《Natural resources forum》2020,44(4):311-333
Using secondary data from a socio-economic quantitative household survey of the North Central region of Vietnam, the main aim of our study is to analyze the causal effect of forest resources on household income and poverty. Based on the observed characteristics of a forest-based livelihood and forest-related activities, we use a propensity score matching (PSM) method to control for potential bias arising from self-selection. The PSM results indicate that households with a forest-based livelihood had a higher level of income and lower poverty rates than did those without. Interestingly, our findings confirm that a forest-based livelihood offers much higher income than any other type of livelihood adopted by local households. Also, the poverty rate among households with a forest-based livelihood is lower than those earning non-labor income or engaged in wage/crop and crop livelihoods. Among households and provinces, we find varying opportunities deriving from forest resources, suggesting that there are potential barriers hindering local households from pursuing a forest livelihood or participating in some forest activities. Therefore, government policy and regulations on forest management should focus on improving the access of households to forest resources, while enhancing the sustainability of these resources. 相似文献