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排序方式: 共有142条查询结果,搜索用时 15 毫秒
51.
Hua Shen Miao Li Bingxuan Wang Ian K. Lai Larry W. Robertson Gabriele Ludewig 《Environmental science and pollution research international》2014,21(10):6384-6399
Environmental pollutants polychlorinated biphenyls (PCBs), especially dioxin-like PCBs, cause oxidative stress and associated toxic effects, including cancer and possibly atherosclerosis. We previously reported that PCB 126, the most potent dioxin-like PCB congener, not only decreases antioxidants such as hepatic selenium (Se), Se-dependent glutathione peroxidase, and glutathione (GSH) but also increases levels of the antiatherosclerosis enzyme paraoxonase 1 (PON1) in liver and serum. To probe the interconnection of these three antioxidant systems, Se, GSH, and PON1, we examined the influence of varying levels of dietary Se and N-acetylcysteine (NAC), a scavenger of reactive oxygen species (ROS) and precursor for GSH synthesis, on PON1 in the absence and presence of PCB 126 exposure. Male Sprague–Dawley rats, fed diets with differing Se levels (0.02, 0.2, or 2 ppm) or NAC (1 %), were treated with a single intraperitoneal injection of corn oil or various doses of PCB 126 and euthanized 2 weeks later. PCB 126 significantly increased liver PON1 mRNA, protein level and activity, and serum PON1 activity in all dietary groups but did not consistently increase thiobarbituric acid levels (thiobarbituric acid reactive substances, TBARS), an indicator of lipid oxidation and oxidative stress, in liver or serum. Inadequate (high or low) dietary Se decreased baseline and PCB 126-induced aryl hydrocarbon receptor (AhR) expression but further increased PCB 126-induced cytochrome P450 1A1 (CYP1A1) expression, the enzyme believed to be the cause for PCB 126-induced oxidative stress. In addition, a significant inverse relationship was observed not only between dietary Se levels and PON1 mRNA and PON1 activity but also with TBARS levels in the liver, suggesting significant antioxidant protection from dietary Se. NAC lowered serum baseline TBARS levels in controls and increased serum PON1 activity but lowered liver PON1 activities in animals treated with 1 μmol/kg PCB 126, suggesting antioxidant activity by NAC primarily in serum. These results also show an unexpected predominantly inverse relationship between Se or NAC and PON1 during control and PCB 126 exposure conditions. These interactions should be further explored in the development of dietary protection regimens. 相似文献
52.
Determinants of paternity success in the spider Pholcus phalangioides (Pholcidae: Araneae): the role of male and female mating behaviour 总被引:1,自引:0,他引:1
In double mating experiments, we examined whether and to what extent various male and female behavioural traits influence
the course of mating and fertilization success in the cellar spider. In males, we focussed on pre-copulatory behaviour and
on the rhythmic twisting movements that the male performs with his pedipalps during copulation. In females, we investigated
remating decisions and the effect of female termination of copulation. Second males fertilized a high proportion of the eggs
(P
2: median 89%) despite much shorter second matings, with high variation in relative paternity success. The number of pedipalp
movements (PPMs) of either male was a better predictor of paternity than copulation duration. Our results suggest that in
second matings, PPMs help to remove sperm from previous males, whereas in first matings a high number of PPMs enhances fertilization
success, either due to numerical sperm competition or cryptic female choice. Furthermore, we found a negative male age effect
on paternity in second matings, implying that age-related deterioration of spermatozoa may promote variation in fertilization
success. Female receptivity decreased significantly in second matings; only 70% of the females remated. Females that accepted
a second copulation were found to terminate these much earlier and with higher probability than first matings. This suggests
that the intensity of conflict between the sexes is higher in second matings. Increased intensity of sexual conflict may be
responsible for stronger selection on male traits, as pre-copulatory behaviour and age only affected male copulatory performance
and paternity in second matings.
Electronic Publication 相似文献
53.
Stochastic analysis to assess the spatial distribution of groundwater nitrate concentrations in the Po catchment (Italy) 总被引:5,自引:0,他引:5
Cinnirella S Buttafuoco G Pirrone N 《Environmental pollution (Barking, Essex : 1987)》2005,133(3):569-580
A large database including temporal trends of physical, ecological and socio-economic data was developed within the EUROCAT project. The aim was to estimate the nutrient fluxes for different socio-economic scenarios at catchment and coastal zone level of the Po catchment (Northern Italy) with reference to the Water Quality Objectives reported in the Water Framework Directive (WFD 2000/60/CE) and also in Italian legislation. Emission data derived from different sources at national, regional and local levels are referred to point and non-point sources. While non-point (diffuse) sources are simply integrated into the nutrient flux model, point sources are irregularly distributed. Intensive farming activity in the Po valley is one of the main Pressure factors Driving groundwater pollution in the catchment, therefore understanding the spatial variability of groundwater nitrate concentrations is a critical issue to be considered in developing a Water Quality Management Plan. In order to use the scattered point source data as input in our biogeochemical and transport models, it was necessary to predict their values and associated uncertainty at unsampled locations. This study reports the spatial distribution and uncertainty of groundwater nitrate concentration at a test site of the Po watershed using a probabilistic approach. Our approach was based on geostatistical sequential Gaussian simulation used to yield a series of stochastic images characterized by equally probable spatial distributions of the nitrate concentration across the area. Post-processing of many simulations allowed the mapping of contaminated and uncontaminated areas and provided a model for the uncertainty in the spatial distribution of nitrate concentrations. 相似文献
54.
55.
56.
For the first time, concentrations of the long lived radon progenies 210Pb, 210Bi and 210Po were measured in the mine atmosphere of the so called "healing gallery" in Badgastein, Austria, a region famous for its radioactive springs. These investigations were performed in order to study the radioactive equilibrium between the 210Pb-210Bi and the 210Pb-210Po pairs so as to gain more information about the aerosol-forming processes in the mine. The particle size distribution of the aerosols was determined under different ventilation conditions. Six-stage and eight-stage cascade impactors with working ranges from 0.15 to5 µm and from 0.063 to 8 µm, respectively, were used to collect the mine aerosols. These samples were analysed in the laboratory and measured by liquid scintillation spectrometry. The most surprising results were found under full ventilation, when the total activity concentrations of 210Pb, 210Bi and 210Po were 4.6, 2.0 and 16.5 mBq/m3, respectively. In this case 210Po/210Pb activity ratios ranged between 1.8ǂ.3 and 4.3ǂ.3. These unexpected results were confirmed by the eight-stage impactor samples. For the smallest particles, between 0.062 and 0.125 µm, an even higher value of 7.5 was observed. As outside sources could be excluded, such 210Po enrichments must occur during the aerosol-forming process itself inside the mine. 相似文献
57.
A ring chromosome 19 was found in 14 of 20 metaphases (67 per cent) derived from amniotic fluid cell cultures following amniocentesis because of increased maternal age. Elective termination of the pregnancy revealed a hypotrophic female fetus with mild dysmorphic signs, but no congenital malformations. The case is discussed in relation to three reports in the literature of ring chromosome 19 mosaicism in a phenotypically normal girl, a mentally retarded man, and a boy with normal psychomotor development and minor dysmorphic features. 相似文献
58.
59.
Hildegard Fischer Hans -Jürgen Kretzschmar Gabriele Christoph Volker Neyen 《Environmental Sciences Europe》1994,6(4):189-195
The infra-red (IR) and the gas Chromatographic (GC) methods for the determination of mineral oil hydrocarbons in soils were examined in collaborative trials with regard to their accuracy and reproducibility. Natural, homogenized soils and soils spiked with mineral oil were used as standards. The soil matrix was composed relatively simply. The repeatability and reproducibility values obtained were about 5 % und 23 %, respectively. In contrast, the GC method revealed a considerably higher error range, especially by using the split/splitless technique. The degradation of mineral oil hydrocarbons in soils under different temperatures was investigated by IR throughout one year. The degradation rate at room temperature was about 25 %; at lower temperatures no degradation was detected. Thus, the spiked soils may be used as calibration standards for the mineral oil analysis. 相似文献
60.
Chelli–Cheheb Razika Arzarello Marta Arnaud Julie Berto Claudio Cáceres Isabel Caracausi Sandro Colopi Francesco Daffara Sara Canini Guido Montanari Huguet Rosa Karambatsou Theodora Sala Benedetto Zambaldi Maurizio Berruti Gabriele L. F. 《Die Naturwissenschaften》2020,107(4):1-13
The Science of Nature - Female-only colour polymorphism is rare in birds, but occurs in brood parasitic cuckoos (Cuculidae). Obligate brood parasites leave incubation and parental care to other... 相似文献