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Kazuya Mimura Masayuki Endo Yoko Kawanishi Takeshi Kanagawa Kouji Nagata Keita Terui Makoto Fujii Masayuki Shiraishi Masaya Yamoto Miharu Ito Atsuo Itakura Hiroomi Okuyama Noriaki Usui the Japanese Congenital Diaphragmatic Hernia Study Group 《黑龙江环境通报》2023,43(8):993-1001
This systematic review and meta-analysis aimed to review the optimal timing of delivery at term for neonates with prenatally diagnosed congenital diaphragmatic hernia (CDH). We reviewed the literature up to December 19, 2022 using MEDLINE and the Cochrane Library databases. The inclusion criteria were original articles, comparative studies of CDH neonates delivered at an early term (37–38 weeks of gestation) and at full term (39 weeks of gestation or later), and comparative studies investigating outcomes of CDH neonates. Six studies met the inclusion criteria, including 985 neonates delivered at an early term and 629 delivered at full term. The cumulative rate of survival to discharge showed no significant difference between CDH neonates delivered at an early term (395/515; 76.7%) or at full term (345/467; 73.9%) (risk ratio [RR] 1.01; 95% confidence interval [CI], 0.89–1.16; p = 0.85). Furthermore, the number of neonates requiring oxygen therapy at discharge was not significantly different between CDH neonates delivered at an early term (32/370; 8.6%) and at full term (14/154; 9.1%) (RR, 0.99; 95% CI, 0.36–2.70; p = 0.99). Therefore, the optimal timing of delivery at term for neonates with CDH remains unclear. 相似文献
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Mariane de Fátima Yukie Maeda Maria de Lourdes Brizot Maria Augusta Bento Cicaroni Gibelli Silvia Maria Ibidi Werther Brunow de Carvalho Mara Sandra Hoshida Clarisse Martins Machado Ester Cerdeira Sabino Lea Campos de Oliveira da Silva Thomas Jaenisch Maria Cássia Jacintho Mendes-Correa Philippe Mayaud Rossana Pulcinelli Vieira Francisco HC-FMUSP-Obstetric COVID Study Group 《黑龙江环境通报》2021,41(8):998-1008
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Carmen Mesas Burgos Vikas S. Gupta Peter Conner Björn Frenckner Kevin P. Lally Ashley H. Ebanks Matthew T. Harting For The Congenital Diaphragmatic Hernia Study Group 《黑龙江环境通报》2023,43(10):1265-1273
Background
The aim of this study was to describe the incidence of Congenital Diaphragmatic Hernia, CDH, associated with known or clinically suspected syndromes, and the postnatal outcomes from a large database for CDH.Methods
Data from the multicenter, multinational database on infants with CDH (Congenital Diaphragmatic Hernia Study Group Registry) born from 1996 to 2020 were analyzed. Patients with known or suspected syndromes were grouped and outcome data were analyzed and compared to those without syndromic features.Results
A total of 12,553 patients were entered in the registry during the study period, and 421 had reported known syndromes, representing 3.4% of all CDH cases in the registry. A total of 50 different associated syndromes were reported. In addition to those with clinically suspected genetic conditions, a total rate of genetic syndromes with CDH was 8.2%. The overall survival to discharge for syndromic CDH was 34% and for non-syndromic CDH was 76.7%. The most common were syndromes Fryns syndrome (19.7% of all syndromes, 17% survival), trisomy 18 or Edward syndrome (17.5%, 9% survival), trisomy 21 or Down syndrome (9%, 47% survival), trisomy 13 or Patau syndrome (6.7%, 14% survival), Cornelia de Lange syndrome (6.4% of all syndromes, 22% survival) and Pallister-Killian syndrome (5.5% of all syndromes, 39.1% survival). In addition, 379 cases had reported chromosomal anomalies and 233 cases had clinically suspected syndromes, based on two more dysmorphic features or malformations in addition to CDH, but without molecular diagnosis. The syndromic CDH group had lower birth weight and gestational age at birth and increased incidence of bilateral CDH (2.9%) and rates of non-repair (53%). The length of hospital stay was longer, and larger number of patients needed O2 at 30 days. Extracorporeal life support was used only in 15% of the cases. Those who underwent surgical repair had survival to discharge rates of 73%.Conclusion
Syndromic CDH is rare and only 3.4% of the reported cases of CDH have a known syndrome or association, but, if including patients with two dysmorphic features malformations, in addition to CDH, altogether as many as 8.2% have a diagnosed or suspected genetic condition. These children have with lower survival rates. Given higher rates of non-repair and decreased extracorporeal life support use, along with a high early mortality, decision-making regarding goals of care clearly influences outcomes. Survival varies depending on the genetic cause. Early genetic diagnosis is important and may influence the decision-making. 相似文献37.
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通过分析高速铁路噪声源及声屏障插入后的声传播特征,以Cadna/A噪声计算模式等为基础,建立了基于Cadna/A软件的高速铁路噪声预测模型。利用德国及我国建立在测试基础上的噪声源强数据及噪声预测模式对Cadna/A预测模型进行验证与修正,获得了与我国目前计算规范较一致的噪声预测结果。最后根据铁路声屏障特点,建立了铁路声屏障的Cadna/A计算模型,计算结果与实测结果差异较小。结果表明:只需对Cadna/A软件模型参数做适当验证性修正,该软件即可适用于我国高速铁路噪声环境影响的预测。同时,基于Cadna/A软件的铁路声屏障模型还可用于指导声屏障优化设计工作。 相似文献
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国家环境经济政策研究与试点项目技术组 《中国环境管理》2015,7(3):5-11
2014年是环境经济政策改革元年,环境经济政策建设取得了重要进展和突破。本文综合采用实地调研法、政策追踪法、政策计量分析法对2014年度我国重点环境经济政策的年度进展、成效与问题进行了系统评估与分析,在此基础上提出了下一步我国环境经济政策的改革方向和重点,以及要解决的关键问题。 相似文献