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11.
12.
Juhani Smolander Kalev Kuklane Désirée Gavhed Håkan Nilsson 《International journal of occupational safety and ergonomics》2013,19(2):111-117
The aim of the study was to examine the effects of wearing an ice-vest (ca 1 kg) on physiological and subjective responses in fire fighters. The experiments were carried out on a treadmill in a hot-dry environment. The physical cooling effect of the ice-vest was measured with a thermal manikin. The ice-vest effectively reduced skin temperatures under the vest. On average, heart rate was 10 beats/min lower, the amount of sweating was reduced by 13%, and subjective sensations of effort and warmth were lower during work with the ice-vest compared to work without it. Thermal manikin tests indicated that the useful energy available from the vest for body cooling was rather high (58%). In conclusion, the ice-vest reduces physiological and subjective strain responses during heavy work in the heat, and may promote efficient work time by 10%. 相似文献
13.
Irma Järvelä MD Juhani Rapola Leena Peltonen Lea Puhakka Jouni Vesa Pirkko Ämmälä Riitta Salonen Markku Ryynänen Pertti Haring Aki Mustonen Pirkko Santavuori 《黑龙江环境通报》1991,11(5):323-328
Eleven fetuses at risk for the infantile form of neuronal ceroid lipofuscinosis (INCL, CLN1) were studied using DNA markers and the results were compared with the results of electron microscopy (EM) of chorionic villus specimens from pregnancies in the first or early second trimester of pregnancy. In four cases, the prenatal diagnosis was made independently with both methods, and in seven cases, the EM diagnosis was confirmed postnatally or from autopsy material using RFLP analysis. The two methods gave concordant results in all cases. The DNA analysis based on RFLP haplotypes also for the first time facilitates reliable carrier diagnostics. RFLP analysis based on polymorphic markers closely linked to the INCL locus is now available for prenatal diagnosis of this fatal brain disease, whose biochemical background is totally unknown and for which no treatment is available. 相似文献
14.
Accurate predictions of 13C NMR chemical shifts (standard error approximately 1.7 ppm) are achieved for a subset of chlorinated bornanes by empirical scaling of shifts from GIAO calculations with geometries obtained from HF/6-31G* calculations. The optimized molecular geometries were compared with X-ray structures for three of the toxaphene components most frequently detected in environmental samples (Parlar nos. 26, 50 and 62), and the concordance between the experimental and calculated values was found to be satisfactory. Taken overall, the results indicate that theoretical methods hold great promise for rationalizing 13C NMR chemical shifts in organohalogen compounds. However, it appeared that the DFT/GIAO shifts need to be empirically scaled to achieve good numerical agreement with experimental shifts in chlorinated bornanes. Obviously, there is a need to develop new computational methods to describe the large deshielding effects of chlorine atoms properly. 相似文献
15.
Rasilainen K Suksi J Ruskeeniemi T Pitkänen P Poteri A 《Journal of contaminant hydrology》2003,61(1-4):235-246
Uranium release observed in a rock matrix around water-carrying fractures was studied using U-series disequilibrium (USD) modelling and mass balance calculations. Several release scenarios were tested, with specific attention to the glacial aspects. The release appears to have occurred in two or three violent episodes during the last 300 ky. A release after the last glaciation can be excluded on mass flow grounds. Continuous release for more than 300 ky can be excluded on radioactive disequilibrium grounds. Repeated inflows of oxic glacial meltwater seem to have triggered the release episodes. 相似文献
16.
Friedrich Rinne 《Die Naturwissenschaften》1923,11(39):806-808
17.
Chantal Deden Kornelia Neveling Dimitra Zafeiropopoulou Christian Gilissen Rolph Pfundt Tuula Rinne Nicole de Leeuw Brigitte Faas Thatjana Gardeitchik Suzanne C. E. H. Sallevelt Aimee Paulussen Servi J. C. Stevens Esther Sikkel Mariet W. Elting Merel C. van Maarle Karin E. M. Diderich Nicole Corsten-Janssen Klaske D. Lichtenbelt Guus Lachmeijer Lisenka E. L. M. Vissers Helger G. Yntema Marcel Nelen Ilse Feenstra Wendy A. G. van Zelst-Stams 《黑龙江环境通报》2020,40(8):972-983
Objective
The purpose of this study was to explore the diagnostic yield and clinical utility of trio-based rapid whole exome sequencing (rWES) in pregnancies of fetuses with a wide range of congenital anomalies detected by ultrasound imaging.Methods
In this observational study, we analyzed the first 54 cases referred to our laboratory for prenatal rWES to support clinical decision making, after the sonographic detection of fetal congenital anomalies. The most common identified congenital anomalies were skeletal dysplasia (n = 20), multiple major fetal congenital anomalies (n = 17) and intracerebral structural anomalies (n = 7).Results
A conclusive diagnosis was identified in 18 of the 54 cases (33%). Pathogenic variants were detected most often in fetuses with skeletal dysplasia (n = 11) followed by fetuses with multiple major fetal congenital anomalies (n = 4) and intracerebral structural anomalies (n = 3). A survey, completed by the physicians for 37 of 54 cases, indicated that the rWES results impacted clinical decision making in 68% of cases.Conclusions
These results suggest that rWES improves prenatal diagnosis of fetuses with congenital anomalies, and has an important impact on prenatal and peripartum parental and clinical decision making. 相似文献18.
Juhani Smolander Kalev Kuklane Désirée Gavhed H?kan Nilsson Ingvar Holmér 《International journal of occupational safety and ergonomics》2004,10(2):111-117
The aim of the study was to examine the effects of wearing an ice-vest (ca 1 kg) on physiological and subjective responses in fire fighters. The experiments were carried out on a treadmill in a hot-dry environment. The physical cooling effect of the ice-vest was measured with a thermal manikin. The ice-vest effectively reduced skin temperatures under the vest. On average, heart rate was 10 beats/min lower, the amount of sweating was reduced by 13%, and subjective sensations of effort and warmth were lower during work with the ice-vest compared to work without it. Thermal manikin tests indicated that the useful energy available from the vest for body cooling was rather high (58%). In conclusion, the ice-vest reduces physiological and subjective strain responses during heavy work in the heat, and may promote efficient work time by 10%. 相似文献
19.
Pia Rinne 《Journal of Environmental Policy & Planning》2016,18(1):4-26
This article examines the continuities and changes in newspaper coverage of urban flood governance in Tabasco, southeastern Mexico, where highly destructive floods have made flood risks a socially sensitive and politically contested public issue. The analysis draws upon post-Foucauldian critical discourse analysis, paying special attention to different actors’ discursive strategies to further their agendas amid the shifting forms of environmental governance. We argue that in recent years, discourses that promote integrated flood governance, based on cultural adaptation and social resilience instead of technological control, have become prominent in the media presentation of flood governance. These discourses endorse neoliberal views of flood governance as an issue of public–private co-governance and civil self-responsibility while being reluctant to consider flood risk from the perspective of the uneven distribution of vulnerabilities or as an issue of human rights. 相似文献
20.
Pedestrian behavior and exit selection in evacuation of a corridor - An experimental study 总被引:1,自引:0,他引:1
Simo Heliövaara Juha-Matti KuusinenTuomo Rinne Timo KorhonenHarri Ehtamo 《Safety Science》2012,50(2):221-227
In this paper, we present an experiment whose purpose was to study evacuees’ exit selection under different behavioral objectives. The experiment was conducted in a corridor with two exits located asymmetrically. This geometry was used to make most participants face a nontrivial decision on which exit to use. We analyze the behavior on a macroscopic level using statistical methods. Our results suggest that the members of an evacuating crowd may not be able to make optimal decisions when assessing the fastest exit to evacuate. In addition, the egress time of the whole crowd turns out to be shorter when the evacuees behave egoistically instead of behaving cooperatively. This is an interesting result because many studies on real emergencies show that evacuees tend to cooperate and act altruistically. 相似文献