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71.
A quantitative method for cholinesterases in amniotic fluid using the non-specific substrate α naphthyl acetate and the cholinesterase-specific inhibitor, eserine, is described. This assay was used to test 671 samples of amniotic fluid. The diagnoses for fetal ONTDs, based on the levels of AChE + ChE, were compared with those made for the same samples by the AFP method. Correct diagnoses were made by both methods with amniotic fluid from 35 women carrying fetuses with ONTDs and 631 carrying normal fetuses. There were five false-positive test results for normal fetuses by both methods when the cut-off points were 5 standard deviations above the mean for AFP and above the upper limit of the normal range (7. 5 milliunits) for cholinesterase (AChE + ChE). None of the false-positive samples from either method had the acetylcholinesterase band of activity characteristic of ONTDs after gel electrophoresis. In addition to the above 671 samples, 37 pregnancies with serious fetal abnormalities other than ONTDs were tested. Two were identified by both the AFP and AChE + ChE methods, two more by AFP assay and one other by the AChE + ChE assay. 相似文献
72.
Kathleen Kreiss Michelle G. Gonzalez Kenneth L. Conright Alan R. Scheere 《Environment international》1982,8(1-6)
Dried detergent residue left in carpets after they were shampooed with underdiluted carpet shampoo caused respiratory irritation among most employees in an office building and among all staff members and most children in a day-care center. Symptoms included cough, dry throat, difficulty in breathing, nasal congestion, and headache. Eye irritation was also noted by day-care center staff members. Symptoms persisted for many weeks until the carpets were wet extracted. The major ingredient of the three shampoo products implicated in these two outbreaks and in a third similar report in sodium dodecyl sulfate, a respiratory irritant in mice. Unpublished occupational investigations suggest that soap dust exposure may be associated pulmonary function abnormalities in some exposed workers. Detergent dust is a newly recognized example of indoor air pollution and should be considered when patients or employees complain of building-specific respiratory or eye irritation. 相似文献
73.
Kathleen McNutt 《Journal of Environmental Policy & Planning》2018,20(6):769-780
ABSTRACTTheories of reflexive governance are closely linked with the claim that more traditional modes of coordination have been replaced by networked structures, allowing reflexivity to emerge and reflexive learning to function as a steering mechanism in rapidly changing policy contexts. This paper explores this connection between reflexivity, governance, learning and networks in societal transitions, focusing particularly on the claim that networks will deliver reflexive learning. Using network theories from both policy networks and network governance and a case study of the Canadian agricultural biotechnology (agbiotech) policy network, it suggests that the kind of learning produced in networks will be a function of network structure. In particular, higher order reflexive learning will be compromised by the inevitability of the political struggle for nodality or central place in networks and the ensuing distribution of opportunities for bridging and bonding activities. Networks such as the Canadian agbiotech policy network that may promote learning but not necessarily reflexive learning are increasingly disadvantaged in contemporary policy settings. 相似文献
74.
由于毒性评估项目很难与日渐增长的需要测试的污染物保持同步,所以较难将关注点集中在影响水生生态系统的最为生物相关的污染物上。由于评估潜在毒性污染物所造成的生物影响已被证明是有效的,内生性代谢物的研究(代谢组学)对于剔除那些较低可能造成生物影响的污染物或许有一定帮助,从而找出生物重要性最高的污染物。本研究在北美五大湖流域的18个地点针对置于笼中的黑头软口鲦(Pimephales promelas)进行实验。我们测定了水体温度和水样中的污染物浓度(目标污染物132种,检出86种),并使用1H-NMR谱测量了肝极性提取物中的内生性代谢物。利用偏最小二乘法回归来比对内生性代谢物的相对丰度与污染物浓度和环境温度。结果表明内生性极性代谢物的指标与最多49种污染物存在共同变化。因此我们认为至多52%的检出污染物与内生性代谢物变化的共同变化不显著,表明这些污染物很可能不会在这些地点造成可以检测到的影响。这是通过缩短对于实验地点有着潜在影响的污染物列表从而扫描出检出污染物生物相关性的第一步。类似的信息有助于风险评估者区分不同污染物的重要性并将重点毒性测试放在最为生物相关的污染物上。
精选自Nicol Janecko, Lucie Pokludova, Jana Blahova, Zdenka Svobodova, Ivan Literak. Linking field-based metabolomics and chemical analyses to prioritize contaminants of emerging concern in the Great Lakes basin. Environmental Toxicology and Chemistry: Volume 35, Issue 10, pages 2493–2502, October 2016.
DOI: 10.1002/etc.3409
详情请见http://onlinelibrary.wiley.com/doi/10.1002/etc.3409/full 相似文献
75.
Kathleen Walther Samuel E. Crickenberger Sergio Marchant Peter B. Marko Amy L. Moran 《Marine Biology》2013,160(10):2723-2732
For the antitropical gooseneck barnacle Pollicipes elegans, population-specific physiological temperature tolerance of larvae may serve as a barrier to larval dispersal across the warmest regions of the tropical Pacific Ocean. Thermal tolerance ranges of larvae of three different populations of P. elegans sampled in 2011 and 2012 (Mexico [MX], El Salvador [ES], and Peru [PE]) were investigated by measuring three indicators of physiological performance: swimming activity, oxygen consumption, and lethality or LT50. The thermal tolerance profiles, which include measurable optimum (maximum aerobic performance), pejus (“getting worse”) and pessimum (worst aerobic performance) ranges, of larvae from the three populations were consistent with their characteristic environmental temperatures. In MX, larvae live close to the upper border of their optimum during warm months and so have a limited capacity to tolerate higher-than-normal temperatures. Larvae from the ES population likewise appear to live within their optimum temperature range, but these larvae lack a detectable pessimum range, suggesting they would be unable to cope with temperatures above their pejus range. Larvae from PE have a broad optimum but no pejus range. Different thermal tolerance ranges provide strong evidence for population-dependent physiological adaptations in P. elegans. For the southern (PE) and northern (MX) P. elegans populations, high tropical temperatures are likely to be a strong direct physiological barrier to larval survival and dispersal, which is in contrast to the more thermally tolerant ES population. 相似文献
76.
Kathleen Sherman-Morris 《Environmental Hazards》2013,12(4):201-210
Previous research has acknowledged the importance of mass media in shaping risk perception and as the channel through which people get information during and after disasters. There is still much more to know about the role mass media (but especially the television medium) plays in people's precautionary hazard behaviors. Close to 400 people were surveyed in the Memphis, TN television market about their knowledge and perception of the severe weather threat, and their past experiences with tornadoes and severe thunderstorms.The survey results show that respondents do develop a relationship with their local television weathercaster and also trust their weathercaster during severe weather. This relationship and trust can then predict the likelihood of taking shelter during severe weather. Ultimately, the case will be made that the findings may be useful to future hazards research in other locations. 相似文献
77.
Network theory is commonly used to reveal social interactions and the organisation of interconnected nodes—but has not yet been applied to animal invasions. Non-native species invasions are now considered one of the foremost threats to natural ecosystems and biodiversity. This is the first attempt to assess social network properties within a freshwater fish assemblage invaded by a non-native fish species. We show that invasive sunbleak Leucaspius delineatus is socially more strongly interconnected with native species than the native species with each other. The social networks also reveal characteristics of a ‘small world’ such as low clustering coefficients C and short path lengths L. The findings may indicate potential traits of successful invaders and the implication for the spread of pathogens between individuals within a group of animals that contain a non-native invasive species. The success of establishment and subsequent invasion may be highlighted not only by the capacity of the new species to adapt to the new environment, but also in its capacity to penetrate the social circle of the native community. 相似文献
78.
Kathleen E. Hunt Thomas P. Hahn John C. Wingfield 《Behavioral ecology and sociobiology》1999,45(5):360-369
In males of socially monogamous birds, plasma testosterone (T) typically declines to low levels during the parental phase.
Studies on multiple-brooded species indicate that high T may be incompatible with high-quality paternal care. The length of
the breeding season may affect the costs and benefits of high T and its effect on paternal care. We studied the effect of
experimentally elevated T on paternal care in a single-brooded species with a short breeding season, the Lapland longspur
(Calcarius lapponicus). We monitored T levels and parental behavior in 16 males with subcutaneous T implants, 14 males with empty implants, and
14 unimplanted males. We videotaped nests when nestlings were 2–3 days old and again at 4–5 days. T males with 2- to 3-day-old
young visited nests and fed young less often than control males, and the mates of the T males compensated with elevated visits
and feedings. However, when nestlings were 4–5 days old, T males visited their nests at normal rates – though feeding movements
remained below normal – and T females visited and fed at normal rates. Nestling mass and nest success were similar in both
groups. Overall, high T suppresses paternal care in Lapland longspur males. The partial improvement of paternal care when
nestlings are older, despite high T, may be related to the short 6-week breeding season of this arctic species, and the consequently
reduced benefits of sexual behavior late in the breeding season.
Received: 2 February 1998 / Accepted after revision: 2 November 1998 相似文献
79.
Dennis Ojima Luis Garcia E. Elgaali Kathleen Miller Timothy G. F. Kittel Jill Lackett 《Journal of the American Water Resources Association》1999,35(6):1443-1454
ABSTRACT: This paper reports on the current assessment of climate impacts on water resources, including aquatic ecosystems, agricultural demands, and water management, in the U.S. Great Plains. Climate change in the region may have profound effects on agricultural users, aquatic ecosystems, and urban and industrial users alike. In the central Great Plains Region, the potential impacts of climate changes include changes in winter snowfall and snow-melt, growing season rainfall amounts and intensities, minimum winter temperature, and summer time average temperature. Specifically, results from general circulation models indicate that both annual average temperatures and total annual precipitation will increase over the region. However, the seasonal patterns are not uniform. The combined effect of these changes in weather patterns and average seasonal climate will affect numerous sectors critical to the economic, social and ecological welfare of this region. Research is needed to better address the current competition among the water needs of agriculture, urban and industrial uses, and natural ecosystems, and then to look at potential changes. These diverse demands on water needs in this region compound the difficulty in managing water use and projecting the impact of climate changes among the various critical sectors in this region. 相似文献
80.
Bruce W. Hardy Kathleen Hall Jamieson 《Environmental Communication: A Journal of Nature and Culture》2017,11(2):205-217
Unusually cold winters, a slowing in upward global temperatures, or an increase in Arctic sea ice extent are often falsely cast as here-and-now disconfirmation of the scientific consensus on climate change. Such conclusions are examples of “end point bias,” the well documented psychological tendency to interpret a recent short-term fluctuation as a reversal of a long-term trend. End point bias poses a challenge to those trying to communicate cross-decade climate warming trends. In this study, we demonstrate that exposure to misleading scientific information on FoxNews.com that evokes end point bias can affect the beliefs of liberals and moderates as well as conservatives. We also show that the leveraging-involving-visualizing-analogizing communication model can reduce the effects of endpoint bias among moderates and liberals at the same time as it dampens both the ideological and endpoint biasing of conservatives. 相似文献