Second trimester prenatal diagnosis of the Jarcho-Levin syndrome

The Jarche–Levin syndrome (spondylothoracic dysostosis) is a rare autosomal recessive disorder characterized by a short neck, short trunk and a constricted thorax due to multiple rib and vertebral defects; other visceral malformations are occasionally present. Most cases die in infancy due to respiratory failure. In this report we describe two cases in one family from the United Kingdom. Prenatal diagnosis by ultrasound examination during the second trimester was successfully accomplished in the second case.     

Beyond the brink: STEM women and resourceful sensemaking after burnout

This paper attends to the burnout recovery experiences of women in science, technology, engineering, and mathematics (STEM) and qualitatively explores how these individuals renegotiate, reorient, and recalibrate their work trajectories after burnout; an ambiguous and shocking event that has been shown to cause lingering disruption for both individuals and organizations (Salvagioni et al., 2017). We bring together conservation of resources (COR) theory and a sensemaking approach, illustrating how attention to sensemaking reveals the dynamics of resource allocation during times of disruption and loss; that is, the relational negotiation of protecting, investing, and fostering resources, including and importantly to burnout, a recognizable sense of recovery. Our rich qualitative analysis and findings reveal three sensemaking plotlines (Combative, Regenerative, and Promissory) through which rituals of resource management take place. Insights from this study provide a theoretical exposition for the post-burnout experience, illuminating the black box between burnout and recovery. We present a number of theoretical and practical contributions in developing the scholarly vistas surrounding (post-)burnout studies and STEM careers that better conceptualize (i) how marginalized members in highly instituted settings experience the aftermath of burnout and (ii) the broader implications this has for the sustainability of workforces.     

Recent advances in econometric estimation of materials substitution

Interest in substituting reproducible inputs such as capital and labour for non-renewable materials is principally motivated by two factors — the short-run concern about supply disruptions on the part of producing countries and the long-run concern about the exhaustion of depletable natural resources. In this paper, techniques for estimating elasticities of substitution between inputs (ie between different materials or between material aggregates and other input aggregates) from production and cost functions are discussed, and the recent literature that makes use of these techniques is reviewed.     

The valuation of forest carbon services by Mexican citizens: the case of Guadalajara city and La Primavera biosphere reserve

Adequate demand for, and recognition of, forest carbon services is critical to success of market mechanisms for forestry-based conservation and climate change mitigation. National and voluntary carbon-offsetting schemes are emerging as alternatives to international compliance markets. We developed a choice experiment to explore determinants of local forest carbon-offset valuation. A total of 963 citizens from Guadalajara in Mexico were asked to consider a purchase of voluntary offsets from the neighbouring Biosphere Reserve of La Primavera and from two alternative more distant locations: La Michilía in the state of Durango and El Cielo in Tamaulipas. Surveys were applied in market stall sessions and online using two different sampling methods: the snowball technique and via a market research company. The local La Primavera site attracted higher participation and valuation than the more distant sites. However, groups particularly interested in climate change mitigation or cost may accept cost-efficient options in the distant sites. Mean implicit carbon prices obtained ranged from $6.79 to $15.67/tCO_2eq depending on the surveying methodology and profile of respondents. Survey application mode can significantly affect outcome of the experiment. Values from the market stall sessions were higher than those from the snowball and market research samples obtained online; this may be linked to greater cooperation associated with personal interaction and collective action. In agreement with the literature, we found that valuation of forest carbon offsets is associated with cognitive, ethical, behavioural, geographical and economic factors.     

Cycles in natural-resource commodity prices: An analysis of the frequency domain

A model is derived that relates price cycles to investment behavior in the mineral industries and predicts that these cycles will be roughly twice as long as the investment period (the period between the investment decision and the project completion). Spectral techniques are used to estimate the principal cycles in metal and fuel prices. For the metals, the estimated cycle lengths reinforce the model predictions. However, no significant cycles are found in the prices of the fuels. The lead-lag relationships between prices of different commodities are also investigated and are found to be significant for those that are jointly produced.     

Container contamination as a possible source of a diarrhoea outbreak in Abou Shouk camp, Darfur province, Sudan

Diarrhoea is one of the five major causes of death in an emergency setting and one of the three main causes of death in children (Curtis and Cairncross, 2003). In June 2004, an outbreak of shigellosis was confirmed in Abou Shouk camp in the Northern Darfur province of Sudan. As water testing showed no contamination, it was assumed that post-collection contamination was happening. The decision was taken to launch a programme of mass disinfection of all water containers in order to break the contamination cycle. Diarrhoea figures from the clinics showed a fall in cases following the cleaning campaign. It is extremely difficult to obtain good and statistically rigorous data in an emergency setting, the priority being to intervene rapidly to prevent further cases of diarrhoea. However, the results do appear to indicate that the disinfection programme has had an impact on the prevalence of bloody and watery diarrhoea.     

The lead content and isotopic composition of british coals and their implications for past and present releases of lead to the UK environment

More than 60 coal samples, predominantly from the principal coalfields of England and Wales (25) and Scotland (30), were analysed for lead by AAS and for stable lead isotopes by ICPMS. While the average lead content of Scottish coal, 23.9mg kg^–1, was more than double that of coal from England and Wales, 11.0mg kg^–1, the corresponding mean ²⁰⁶Pb/²⁰⁷Pb ratios (± 1 s.d.) were nearly identical, at 1.181±0.011 and 1.184±0.006, respectively. In the light of the lead isotopic signatures of British coals and of both indigenous (²⁰⁶Pb/²⁰⁷Pb 1.17) and imported Australian (²⁰⁶Pb/²⁰⁷Pb 1.04) lead ores, an approach based on estimated lead emissions from these sources and the deconvolution of the historical lead and ²⁰⁶Pb/²⁰⁷Pb records preserved in lake sediments, peat bogs and archival herbage material indicates that coal combustion became an increasingly significant contributor to atmospheric lead deposition in the UK during the period 1830–1930, especially after the onset of Englands decline as a major location of lead mining and smelting in the late19th Century. Since 1930 and the introduction of leaded petrol, the atmospheric ²⁰⁶Pb/²⁰⁷Pb ratio in the UK has been strongly influenced by carexhaust emissions of comparatively ²⁰⁶Pbdepleted lead of predominantly Australian origin, counterbalanced to some extent by coalcombustion emissions of lead, although these have fallen dramatically since the mid1950s. Nevertheless, with the introduction and substantial uptake of unleaded petrol in the UK during the last decade, even the declining releases from coal, along with contributions from other sources, are continuing to affect the atmospheric lead content and ²⁰⁶Pb/²⁰⁷Pb ratio.