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41.
Hiller Edgar Pilková Zuzana Filová Lenka Jurkovič Ľubomír Mihaljevič Martin Lacina Petr 《Environmental science and pollution research international》2021,28(5):5455-5471
Environmental Science and Pollution Research - It is well known that road transport emits various trace elements into the environment, which are deposited in soils in the vicinity of roads,... 相似文献
42.
Pavlova Ekaterina Pashkunova-Martic Irena Schaier Martin Petrova Emilia Gluhcheva Yordanka Dorkov Peter Helbich Thomas H. Keppler Bernhard Koellensperger Gunda Ivanova Juliana 《Environmental science and pollution research international》2021,28(6):6784-6795
Environmental Science and Pollution Research - In this study, we compare the effects of deferiprone (Def) and tetraethylammonium salt of salinomycinic acid (Sal) on lead (Pb)-induced toxicity in... 相似文献
43.
Anders Malmendal Jesper Givskov Sørensen Johannes Overgaard Martin Holmstrup Niels Chr. Nielsen Volker Loeschcke 《Die Naturwissenschaften》2013,100(5):417-427
We investigated the global metabolite response to artificial selection for tolerance to stressful conditions such as cold, heat, starvation, and desiccation, and for longevity in Drosophila melanogaster. Our findings were compared to data from other levels of biological organization, including gene expression, physiological traits, and organismal stress tolerance phenotype. Overall, we found that selection for environmental stress tolerance changes the metabolomic 1H NMR fingerprint largely in a similar manner independent of the trait selected for, indicating that experimental evolution led to a general stress selection response at the metabolomic level. Integrative analyses across data sets showed little similarity when general correlations between selection effects at the level of the metabolome and gene expression were compared. This is likely due to the fact that the changes caused by these selection regimes were rather mild and/or that the dominating determinants for gene expression and metabolite levels were different. However, expression of a number of genes was correlated with the metabolite data. Many of the identified genes were general stress response genes that are down-regulated in response to selection for some of the stresses in this study. Overall, the results illustrate that selection markedly alters the metabolite profile and that the coupling between different levels of biological organization indeed is present though not very strong for stress selection at this level. The results highlight the extreme complexity of environmental stress adaptation and the difficulty of extrapolating and interpreting responses across levels of biological organization. 相似文献
44.
Nicholas Tatrallyay Martin Stadelmann 《Mitigation and Adaptation Strategies for Global Change》2013,18(7):903-919
This study analyzes the effectiveness and efficiency of the two principal United Nations (UN) climate change mitigation finance mechanisms, the Clean Development Mechanism (CDM) and the Global Environment Facility (GEF). The realised abatement and costs of the two mechanisms in India and Brazil (using data from 28 GEF and 233 CDM project documents) are compared with theoretical marginal abatement cost curves, based on bottom-up technology studies. We find that both mechanisms have focused on negative and low-cost abatement potential but still leave substantial theoretical potential in this cost range untapped. CDM has more effectively harvested abatement potential of industrial gases and methane emissions, whereas GEF has more successfully targeted demand-side energy efficiency (EE) and transport emission reduction opportunities. CDM has excelled at capturing abatement potential in areas with a limited understanding of abatement, highlighting the shortcomings of theoretical estimates (such as Marginal Abatement Cost Curves) and the benefits of a market mechanism. In some sectors and technologies (particularly renewable energy), the two mechanisms overlapped, which suggests a need for better coordination in the future. 相似文献
45.
Power matters in closing the phenotyping gap 总被引:1,自引:0,他引:1
Meyer CW Elvert R Scherag A Ehrhardt N Gailus-Durner V Fuchs H Schäfer H Hrabé de Angelis M Heldmaier G Klingenspor M 《Die Naturwissenschaften》2007,94(5):401-406
Much of our understanding of physiology and metabolism is derived from investigating mouse mutants and transgenic mice, and
open-access platforms for standardized mouse phenotyping such as the German Mouse Clinic (GMC) are currently viewed as one
powerful tool for identifying novel gene-function relationships. Phenotyping or phenotypic screening involves the comparison of wild-type control mice with their mutant or transgenic littermates. In our study, we explored
the extent to which standardized phenotyping will succeed in detecting biologically relevant phenotypic differences in mice
generated and provided by different collaborators. We analyzed quantitative metabolic data (body mass, energy intake, and
energy metabolized) collected at the GMC under the current workflow, and used them for statistical power considerations. Our
results demonstrate that there is substantial variability in these parameters among lines of wild-type C57BL/6 (B6) mice from
different sources. Given this variable background noise in mice that serve as controls, subtle phenotypes in mutant or transgenic
littermates may be overlooked. Furthermore, a phenotype observed in one cohort of a mutant line may not be reproducible (to
the same extent) in mice coming from a different environment or supplier. In the light of these constraints, we encourage
researchers to incorporate information on intrastrain variability into future study planning, or to perform advanced hierarchical
analyses. Both will ultimately improve the detectability of novel phenotypes by phenotypic screening.
Carola W. Meyer and Ralf Elvert contributed equally to this work. 相似文献
46.
On December 1, 2000, new legislation came into force in Victoria, Australia, that involved a framework for the procedure to be followed by the police for the detection of drivers impaired by drugs other than alcohol. An integral part of the procedure is the use of performance tests known as the standardized field sobriety tests (SFSTs) and the analysis of blood samples for the presence of drugs other than alcohol. This paper outlines the new legislative framework and the drug impairment detection procedures currently in place in Victoria. This paper also evaluates the data collected using the framework for the first five years since implementation in Victoria. 相似文献
47.
U. Martin Persson Christian Azar 《Mitigation and Adaptation Strategies for Global Change》2007,12(7):1277-1304
The possibility of adopting national targets for carbon dioxide (CO2) emissions from tropical deforestation in a future international climate treaty has received increasing attention recently.
This attention has been prompted by proposals to this end and more intensified talks on possible commitments for developing
countries beyond the United Nations Framework Convention on Climate Change Kyoto Protocol. We analyze four main scientific
and political challenges associated with national targets for emissions from tropical deforestation: (1) reducing the uncertainties
in emission inventories, (2) preserving the environmental integrity of the treaty, (3) promoting political acceptance and
participation in the regime, and (4) providing economic incentives for reduced deforestation. We draw the following conclusions.
(1) Although there are large uncertainties in carbon flux from deforestation, these are in the same range as for other emissions
included in the current Kyoto protocol (i.e., non-CO2 GHGs), and they can be reduced. However, for forest degradation processes the uncertainties are larger. A large challenge
lies in building competence and institutions for monitoring the full spectrum of land use changes in developing countries.
(2 and 3) Setting targets for deforestation is difficult, and uncertainties in future emissions imply a risk of creating ‘tropical
hot air’. However, there are proposals that may sufficiently deal with this, and these proposals may also have the advantage
of making the targets more attractive, politically speaking. Moreover, we conclude that while a full carbon accounting system
will likely be politically unacceptable for tropical countries, the current carbon accounting system should be broadened to
include forest degradation in order to safeguard environmental integrity. (4) Doubts can be cast over the possible effect
a climate regime alone will have on deforestation rates, though little thorough analysis of this issue has been made.
相似文献
U. Martin PerssonEmail: |
48.
Today and in the Tertiary, the geographical distribution of castorids is limited throughout all of the northern continents.
Fossils of the Castoridae genus Steneofiber are abundant in many localities of Eurasia from the late Oligocene to Pliocene period. Recently, Steneofiber fossils were discovered in two localities of northern Thailand, Mae Moh and Chiang Muan coal mines, in layers of late middle
Miocene age. These discoveries represent the first records of castorids from Southeast Asia and correspond to their southernmost
known range. The focus of this study is to describe this new Thai species of Steneofiber and to define its wear stages from the molar occlusal surfaces by using micro-CT scan analysis. The CT scan technique permits
the analysis of the virtual occlusal surface changes from wear, allowing easier comparison to related species of Steneofiber cheek teeth without destroying the teeth. The new species, Steneofiber siamensis n. sp., can be distinguished from the other species of Steneofiber by several distinct characters, longer mesostriid on p4, presence of premesostria and metastria on P4, which are smaller
than most of the other known species. The occurrence of this new castorid also supports a subtropical to tropical paleoclimate
for these two localities of northern Thailand. 相似文献
49.
Most systems used to locate discrete gamma-ray sources involve systematically passing a detector over the search area while seeking a significant increase in the observed count-rate. This paper discusses the ways in which such systems may be designed to maximise the probability of locating a source. It is shown that optimised systems use a collimated, energy-discriminating detector and overlapping counting intervals determined by the scanning geometry and speed. 相似文献
50.
Leona Bohdalkova Martin Novak Frantisek Buzek Jakub Kreisinger Richard Bindler Katerina Pazderu Petra Pacherova 《Mitigation and Adaptation Strategies for Global Change》2014,19(7):997-1010
There are fears that global warming will lead to degradation of peatlands, higher emissions of greenhouse gases from peat, and accelerated warming. Anaerobic decomposition of organic soils produces methane (CH4), a potent greenhouse gas. Two peat bogs differing in mean annual temperature, Velke Darko (VD, Czech Republic, 7.2 °C), and Stor Åmyran (SA, Sweden, 4.0 °C), were selected for a comparative study of how organic soils in different climatic zones will respond to warmer and drier conditions. Twenty peat cores from each bog were incubated in growth chambers. Under present-day summer conditions, VD produced 14 times more CH4 than SA. Two different warming scenarios were used. Peat-core replicates were kept at temperatures of 11 versus 16 °C, and 11 versus 22 °C. From 11 to 16 °C, the CH4 production slightly decreased at SA, and slightly increased at VD. From 11 to 22 °C, the CH4 production increased 9 times at SA, but slightly decreased at VD. After an 8-month incubation, peat cores under drying conditions (water table at ?14 cm) were compared to samples with original water table (?2 cm). Drying conditions led to a steeper reduction in CH4 production at VD, compared to SA. The CH4 production decreased more than 100 times at VD. Then, the combined effect of simultaneous warming and drying at 11 and 22 °C was studied. We did not find any significant effect of interactions between increasing temperature and decreasing water table level. Overall, the warmer site VD responded more strongly to the simulated climate change than the colder site SA. 相似文献