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41.
Judith Bell Jørgen Hilden Francis Bowling John Pearn Arthur Brownlea Nicole Martina 《黑龙江环境通报》1986,6(1):1-11
From the public health point of view, several formal attempts have been made to measure the impact of prenatal diagnosis (PND) on the incidence of Down's Syndrome (DS), but the results have varied widely. The impact of PND (reduction in the birth rate of chromosomally abnormal neonates) is related to utilization rates but quantitative estimates of this have not been established. In a three-year (1981–1983) total population study from Queensland, Australia, we present results to measure the impact of a voluntary PND programme on the birth incidence of DS, and also other chromosomally abnormal births. Utilization rates for the PND service were 15·5 per cent in that population of mothers 35 years and over. Numbers and rates of all cases of chromosomal abnormalities are presented, subclassified by type of diagnosis–-either by PND or by clinical diagnosis after birth. For the total population, 7·3 per cent of cases of DS were detected prenatally, and 15·4 per cent of all chromosome abnormalities. (A method for measuring the impact of PND is described.) Using this in conjunction with our demographic data, we estimate that with a 15 per cent utilization rate of PND by older mothers, 14 per cent of DS births can be prevented in this age group, or a 5 per cent overall reduction can be achieved if mothers of all ages are considered. One index–-the ratio of the percentage of DS births which are preventable compared with the population utilization rates of PND–-has potential for widespread use. Queensland data for this ratio is 0·34, a figure consistent with that from other studies. Thus a 3·5 per cent drop in the overall DS birth rate may be expected for each 10 per cent increase in the utilization rates of PND for mothers of 35 years and over. A diagram is presented which may serve as a model for improved data collection and better impact estimates in the future. 相似文献
42.
Isolation and identification of intermediates from biodegradation of low chlorinated biphenyls (Delor-103) 总被引:4,自引:0,他引:4
Tríska J Kuncová G Macková M Nováková H Paasivirta J Lahtiperä M Vrchotová N 《Chemosphere》2004,54(6):725-733
Microorganism Pseudomonas species P2 metabolizes polychlorinated biphenyls (PCBs) and biphenyl, producing the whole spectrum of intermediates, among them coloured intermediates, which are suitable for the monitoring of PCBs degradation by optical sensors. Knowledge of chemical structures and conditions of development of colour metabolites is necessary for application of optical analytical methods. The main goal of this work was the isolation and identification of intermediates from the biodegradation of the mixture of low chlorinated biphenyls (Delor-103), which is based on the solid phase extraction (SPE) of the whole mixture using LiChrolut EN cartridges, then silylation of the extract as one way to the identification of one part of intermediates by GC-MS, and acetylation of the extract as a way for the further concentration and analysis of more polar chlorobiphenylols and chlorobiphenyldiols. The combination of SPE and following acetylation allows to obtain chlorobiphenylols and chlorobiphenyldiols as an almost pure fraction. The acetylation method could be also used instead SPE procedure with the same final concentration effect. Using the simulation mass spectrometry program, two new compounds, dihydrodihydroxytrichloro- and tetrahydrodihydroxytrichlorobiphenyl, as silylderivatives, were identified. 相似文献
43.
Kilian Weigand Kurt Weigand Mathias Schemmerer Martina Müller Juergen J. Wenzel 《Food and environmental virology》2018,10(2):167-175
In the last few years it has been realized that the hepatitis E virus (HEV) is endemic in most industrialized countries and that it is a zoonotic disease. Potential reservoirs for HEV have been identified to be wild boars and deers, but HEV has also been found in domestic pigs and other animals. Due to the probable spread of the virus via contaminated food or contact to infected animals, HEV antibodies are present in more than 16% of the German adult population and rates are increasing with age. We collected blood from 104 wild boars in southern Germany and the border region of Alsace. We found an anti-HEV seroprevalence of 11.5% in our cohort, using ELISA. Furthermore, we observed active infection in 3.85% of the animals by positive HEV PCR in the sera of the boars. In our cohort, no regional differences of seroprevalence or active infection were seen. Sequencing revealed rather close homology of some detected HEV sequences to genotypes isolated from patients in Germany. Hence wild boars are a potential source of HEV infection in Middle Europe and the rate of infectious animals is quite high. 相似文献
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45.
Mattia Falaschi Simone Giachello Elia Lo Parrino Martina Muraro Raoul Manenti Gentile Francesco Ficetola 《Conservation biology》2021,35(5):1530-1539
Many organisms live in networks of local populations connected by dispersing individuals, called spatially structured populations (SSPs), where the long-term persistence of the entire network is determined by the balance between 2 processes acting at the scale of local populations: extinction and colonization. When multiple threats act on an SSP, a comparison of the different factors determining local extinctions and colonizations is essential to plan sound conservation actions. We assessed the drivers of long-term population dynamics of multiple amphibian species at the regional scale. We used dynamic occupancy models within a Bayesian framework to identify the factors determining persistence and colonization of local populations. Because connectivity among patches is fundamental to SSPs dynamics, we considered 2 measures of connectivity acting on each focal patch: incidence of the focal species and incidence of invasive crayfish. We used meta-analysis to summarize the effect of different drivers at the community level. Persistence and colonization of local populations were jointly determined by factors acting at different scales. Persistence probability was positively related to the area and the permanence of wetlands, whereas it was negatively related to occurrence of fish. Colonization probability was highest in semipermanent wetlands and in sites with a high incidence of the focal species in nearby sites, whereas it showed a negative relationship with the incidence of invasive crayfish in the landscape. By analyzing long-term data on amphibian population dynamics, we found a strong effect of some classic features commonly used in SSP studies, such as patch area and focal species incidence. The presence of an invasive non-native species at the landscape scale emerged as one of the strongest drivers of colonization dynamics, suggesting that studies on SSPs should consider different connectivity measures more frequently, such as the incidence of predators, especially when dealing with biological invasions. 相似文献
46.
Background and aim Grassy field margins have a high relevance in agricultural landscapes regarding the preservation of typical arthropod communities, their biodiversity and the ecological system functions linked with it. The structure of terrestrial communities is affected by anthropogenic impairment, which can lead to the replacement of sensitive by more tolerant species. The negative influence of pesticides on fauna and flora as well as the associated functional aspects (ecological system functions) and the reduction of biodiversity are undisputed since longer for agrarian systems and can also be assumed for grassy field margins due to spray-drift. The case study presented here examined the effect of influences related to utilization on the plant and arthropod communities of grassy field margins. Reference sites, on which due to missing farming in the direct surrounding countryside no utilization influences on the communities were present, were compared to non-target sites, on which these influences could not be excluded. Sites in three German macrochores were examined: in the Jülicher Börde, at the northeastern edge of the Leipziger low lands and in the area Mainfranken near Würzburg, all of them intensely used agricultural landscapes. Beside the vegetation, the epigeic arthropod communities of carabid beetles, spiders, springtails, hymenopterans, hover flies and ladybirds as well as abiotic parameters were included in the analysis. The aim of the study was the development of a statistical exclusion procedure which is capable to quantify the amount of variation in field community data which can be attributed to isolated factors. Special attention was paid to non-observable utilization impacts like undocumented pesticide application. The extraction of patterns of residual variance allowed for the uncovering of masked effects on a scale below the obvious abundance pattern. Materials and methods The variability in the species composition was visualized with the help of non-metric multi-dimensional scaling (NMDS). Indicator species analysis revealed those species which could be recognized as statistically significant indicators for local conditions. The relationship between the species composition and the environmental factors was statistically modeled by canonical correspondence analysis. By variance partitioning it was possible to extract the variance portion which could be bound to a set of covariables. For the remaining residual variance it could not be excluded that this resulted from a pesticide influence. Results The analyses based on the ecological distance (Bray-Curtis) showed that the communities in references sites and non-target sites could be clearly distinguished in all three landscapes. Based on the portions of variance which could be explained statistically by a utilization related influence, two different directions of reaction to the utilization related variables could be stated. On the one hand there were sensitive species, showing reduced abundances in the non-target sites, on the other hand there were species increasing in abundance in the non-target sites, recruiting from the group of strong competitors. Discussion By the use of residual variances a clear influence of utilization related parameters on the community of soil arthropods and vegetation could be shown. The observed abundances shifts between reference sites and non-target sites in the raw data were attributed to a multi-dimensional factor complex which could be split up by the use of partial ordination methods, quantifying the relationships to the utilization related parameters. It was demonstrated that special utilization correlated patterns could be found in the raw data after eliminating the influence of the covariables. Conclusions Utilization related influences in the non-target sites evened out the characteristic communities for the three landscapes towards a comprehensive, ubiquitous species composition. The hypothesis of decreasing abundance of sensitive species and the augmentation of tolerant species due to a potential pesticide influence could be underpinned and quantified. Sensitive species which showed a significant reduction in abundance between reference and non-target sites showed a much higher sensitivity to the influences and thus were assigned a higher indicator potential than tolerant species. From the group of the sensitive species Pardosa palustris and Poecilus cupreus could be isolated as two promising macrochore-specific indicator species for the masked effects. Recommendations and perspectives A macrochore-specific assessment of utilization effects was requested for future studies due to the different sensitivities of the species in the three landscapes. The elaboration and specifying of reference conditions for terrestrial agrarian systems is an important task for the future. The presented approach deduces a macrochore-specific, complex effect pattern of anthropogenic impairment on terrestrial species communities. It can be used to extract masked effects and by this facilitates a more sustainable use of e.g. plant protection products. Furthermore it provides an opportunity to validate evaluation systems for the effects of utilization impacts on terrestrial vegetation and arthropods. Additionally the species sensitivities with respect to the macrochores allow a regionalized assessment of ecotoxicological effects and the integration into spatially explicit effect assessment models. 相似文献
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48.
Diversity of chlorobiphenyl-metabolizing bacteria and their biphenyl dioxygenases in contaminated sediment 总被引:1,自引:0,他引:1
Bacteria and bacterial communities in sites contaminated with polychlorinated biphenyls have been extensively studied in the past decades. However, there are still major gaps in the knowledge of environmental processes, especially in the behavior of previously described bacteria in vitro, their real degradation abilities and the enzymes that are involved in the degradation processes. 相似文献
49.
50.
Maurike de Groot-van der Mooren Gert de Graaf Michel E Weijerman Mariette J. V Hoffer Jeroen Knijnenburg Anne-Marie M. F van der Kevie-Kersemaekers Angelique J. A Kooper Els Voorhoeve Birgit Sikkema-Raddatz Laura J. C. M van Zutven Malgorzata Ilona Srebniak Karin Huijsdens-van Amsterdam John J. M Engelen Dominique Smeets Anton H van Kaam Martina C Cornel 《黑龙江环境通报》2021,41(10):1351-1359