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221.
Benthic infauna were sampled from 251 Southern California Bight (SCB) mainland shelf sites in the summer of 1994. Sample sites were selected using a stratified random design, with the primary strata being depth zone, geography, and proximity to point and non-point discharges. Benthic infaunal condition was assessed using the Benthic Response Index (BRI), and by comparing dominant taxa and community parameters (e.g., number of taxa) among strata. Ninety-one percent of sediments in the SCB were found to contain healthy benthic communities. Most stations with altered benthos were located near river mouths, in Santa Monica Bay, or on the Palos Verdes Shelf. Deviations at sites with altered benthic communities were mostly limited to minor changes in species composition, rather than to large declines in diversity or abundance.  相似文献   
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Stormwater is one of the last major untapped urban water resources that can be exploited as an alternative water source in Australia. The information in the current Australian Guidelines for Water Recycling relating to stormwater harvesting and reuse only emphasises on a limited number of stormwater quality parameters. In order to supply stormwater as a source for higher value end-uses, a more comprehensive assessment on the potential public health risks has to be undertaken. Owing to the stochastic variations in rainfall, catchment hydrology and also the types of non-point pollution sources that can provide contaminants relating to different anthropogenic activities and catchment land uses, the characterisation of public health risks in stormwater is complex, tedious and not always possible through the conventional detection and analytical methods. In this study, a holistic approach was undertaken to assess the potential public health risks in urban stormwater samples from a medium-density residential catchment. A combined chemical–toxicological assessment was used to characterise the potential health risks arising from chemical contaminants, while a combination of standard culture methods and quantitative polymerase chain reaction (qPCR) methods was used for detection and quantification of faecal indicator bacteria (FIB) and pathogens in urban stormwater. Results showed that the concentration of chemical contaminants and associated toxicity were relatively low when benchmarked against other alternative water sources such as recycled wastewater. However, the concentrations of heavy metals particularly cadmium and lead have exceeded the Australian guideline values, indicating potential public health risks. Also, high numbers of FIB were detected in urban stormwater samples obtained from wet weather events. In addition, qPCR detection of human-related pathogens suggested there are frequent sewage ingressions into the urban stormwater runoff during wet weather events. Further water quality monitoring study will be conducted at different contrasting urban catchments in order to undertake a more comprehensive public health risk assessment for urban stormwater.  相似文献   
223.
Fetal echocardiography was used to identify a cardiac rhabdomyoma in the second trimester. The combination of this finding with a maternal history of Tuberous Sclerosis allowed the patient and her family to make a more educated decision regarding termination of the pregnancy. Post mortem examination of the fetus confirmed the prenatal findings. This case report demonstrates the importance of ultrasound evaluation of the fetus at risk of recurrence of a genetic syndrome in which one or more anatomical defects might be seen.  相似文献   
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We report a growth-retarded infant with congenital heart disease and maternal isodisomy for chromosome 16. Non-mosaic trisomy 16 was detected at mid-trimester chorionic villus sampling, performed because biochemical screening indicated an increased Down's syndrome risk. Further karyotyping analysis of the placenta, after delivery, showed a 50 per cent mosaic trisomy 16. The infant had an atrioventricular (A-V) canal defect, scoliosis, and several minor dysmorphic features. Although uniparental disomy for chromosome 16 has been reported previously, to our knowledge this is the first case of uniparental isodisomy for chromosome 16 which has been investigated with multiple DNA probes.  相似文献   
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A series of measurements of nicotine vapor and particle concentrations were carried out in a modern office building. The measurement program was designed to document the impact of the new smoking policy (e.g. smoking restricted to two specific areas) on air quality in various parts of the building. Measurements at over 30 locations examined areas where smoking was restricted, where smoking was permitted, and where an air handler shared the load of a designated smoking area. These measurements were taken at the same locations before and after the policy was implemented. The measurement results indicated that: After the policy was implemented, general employee exposure to nicotine vapor (as a surrogate for all environmental tobacco smoke) was reduced by about 98 percent on most floors. Other patterns related to spillover from designated smoking areas and changes in the designated smoking areas themselves are described in the paper. Substantial reductions in exposure to nicotine vapor were found even for those general office areas which had the highest concentrations after the policy was implemented.  相似文献   
227.
Contamination has occurred many non-indurated and bedrock systems wherein the groundwater flows almost exclusively through a network of connected, open fractures. The matrix surrounding the fractures often possesses porosity which allows contaminant diffusion into the matrix. If the diffusion rates are fast relative to the fracture groundwater velocity, transport effects may be predicted by considering the system to be an equivalent porous medium (EPM). The rapidity with which fracture/immobile-matrix equilibrium is established will be determined in part by the: fracture aperture (2b); interfracture spacing (2B); porosity in the immobile matrix im); and the matrix diffusion coefficient (D′). Two systems which are characterized by very different values of the above parameters have been studied by our laboratories. At Alkali Lake, Oregon, the EPM approach describes contaminant transport well. At Bayview Park, Ontario, the EPM approach is not appropriate. Several features of the two sites are compared to illustrate the different nature of these two sites. These features include: (1) natural characteristics of the groundwater systems; (2) contaminant distributions; (3) observed transport; and (4) computed fracture/immobile-matrix diffusion times.  相似文献   
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Objective: The objective of this study was to adapt a previously validated Canadian Culpability Scoring Tool (CCST) to Alberta police report data.

Methods: Police traffic collision reports from motor vehicle (MV) collisions in Calgary and Edmonton (Alberta, Canada) from 2010 to 2014 were used. Adaptation of the CCST was completed with input from personnel within Alberta Transportation, contributing to face and content validity. Two research assistants, given only the information necessary for scoring, evaluated 175 randomly selected MV–MV collisions. Interrater agreement was estimated using kappa (k) and reported with 95% confidence intervals (CIs). Discussion of disagreements between the research assistants and consultation from Alberta Transportation informed the algorithm used in the Alberta Motor Vehicle Collision Culpability Tool (AMVCCT). The AMVCCT was automated and applied to all motorists involved in collisions. Binary logistic regression was used to examine characteristics of the culpable and nonculpable drivers and their effects were reported using odds ratios (ORs) with 95% CIs.

Results: Interrater agreement for the random sample was excellent (k = 0.95; 95% CI, 0.92–0.99). Of those drivers hospitalized, 1,130 (37.54%) were rated not culpable and 1,880 (62.46%) were rated culpable. The odds of being culpable were higher for males than for females (OR = 1.43; 95% CI, 1.23–1.66). The odds of being culpable were higher in those impaired by alcohol than those considered “apparently normal” (OR = 61.10; 95% CI, 22.66–164.75). The odds of being deemed culpable, when compared with drivers >54 years old, were higher for those <25 years old (OR = 1.72; 95% CI, 1.35–2.20) and lower for those in the 40- to 54-year-old age group (OR = 0.78; 95% CI, 0.63–0.96). Driving between 12 a.m. and 6 a.m. resulted in higher odds of being culpable compare with all other 6-h time blocks. Direction and statistical significance remained consistent when applying the tool to all MV collisions. Sensitivity analysis including the removal of single vehicle collisions did not affect the direction or statistical significance of the main results.

Conclusions: The AMVCCT identified a culpable group that exhibited characteristics expected in drivers who are at fault in collisions. The age groups 25–39 and 40–54 demonstrated different results than the CCST. However, this is the only difference that exists in the findings of the AMVCCT compared to the CCST and could exist due to differences between the driving populations in Alberta and British Columbia. It is possible to adapt the CCST to provinces outside British Columbia and, in doing so, we can identify risk factors for collision contribution and not-at-fault drivers who represent the driving population.  相似文献   

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