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11.
Sustainability challenges rarely align with the conventional boundaries of our disciplines, institutions and means of communication. To address these challenges amid real-world complexity, we need to think holistically and collaborate across disciplines. In this paper, we synthesise three themes: (1) more integrated conceptual frameworks; (2) digital visual communication which provides fluid expression of complex ideas and perceptions; and (3) online networks which can empower sustainability initiatives and communicate them across social and institutional barriers at a global scale. Each of these tools can help to overcome persistent barriers to sustainability. When used together, they provide a strategic basis for the design of digital collaboration platforms for addressing sustainability challenges. Using design thinking, we developed a Synergy Map which identifies relationships among a number of barriers to sustainability and conceptual and digital tools which help to address them. The Map identifies the potential for synthesising these tools into effective digital artefacts. We provide several examples and identify characteristics of particular value for overcoming barriers to sustainability. Combining new theoretical developments in sustainability sciences with recent advances in communication and networking technologies offers substantial potential for advancing sustainability on multiple fronts.  相似文献   
12.
Regional Environmental Change - The repercussions of climate change will be felt in various ways throughout both natural and human systems in Sub-Saharan Africa. Climate change projections for this...  相似文献   
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Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an important cause of hereditary stroke. Mutations in the Notch3 gene are clearly causally linked to this progressive vascular disorder. Cerebral ischemic attacks, cognitive decline, strokes, and vascular dementia constitute the major manifestations of this disorder. This report details the prenatal detection of a Notch3 mutation in the fetus of a couple where the father had a known mutation in this gene. This is the first report of a prenatal diagnosis of CADASIL, and another example of a serious, highly penetrant, and relentlessly progressive degenerative genetic disorder presenting decades after birth and for which prenatal diagnosis is an option. Copyright © 2005 John Wiley & Sons, Ltd.  相似文献   
15.
Statistical power analysis has been used to determine the sensitivity of the mussel-watch programme in Hellenic seas, with particular focus placed on the data obtained for metal content in mussels from the Saronicos Gulf during the period 1985-1997. Sample collection was carried out quarterly. Soft tissues of 60-100 similarly sized mussels (Mytilus galloprovincialis) were pooled into six composite samples and analysed by Atomic Absorption Spectroscopy (AAS). The study concludes that the resolution of monitoring programmes employed thus far is sufficiently high to detect temporal trends related to changes in contaminant levels caused either by drastic environmental control (such as those imposed on point-source pollutants) or by sudden increases in contaminant load. However, the detection of more subtle trends, which may be expected in the near future as a result of global pollution-control policies, is likely to require the adoption of much more sensitive programmes. In addition, the review of up-to-date knowledge on metal biology in mussels suggests that factors related to growth and reproduction should be taken into account to remarkably increase the resolution of mussel-watch programmes. Indicative maximum values for components of error to be complied with during routine monitoring are suggested.  相似文献   
16.
Design disciplines have a long history of creating well-integrated solutions to challenges which are complex, uncertain and contested by multiple stakeholders. Society faces similar challenges in implementing the Sustainable Development Goals, so design methods hold much potential. While principles of good design are well established, there has been limited integration of design thinking with sustainability science. To advance this integration, we examine the process of designing MetaMAP: an interactive graphic tool for collaborating to understand social–ecological systems and design well-integrated solutions. MetaMAP was created using Research through Design methods which integrate creative and scientific thinking. By applying design thinking, researchers and practitioners from different backgrounds undertook multiple cycles of problem framing, solution development, testing and reflection. The testing was highly collaborative involving over 150 people from diverse disciplines in workshops, case studies, interviews and critique. Reflecting on this process, we discuss design principles and opportunities for integrating design thinking with sustainability science to help achieve Sustainable Development Goals.  相似文献   
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Geochemical and mineralogical changes were evaluated at a field Fe0-PRB at the Oak Ridge Y-12 site concerning operation performance during the treatment of U in high NO3- groundwater. In the 5-year study period, the Fe0 remained reactive as shown in pore-water monitoring data, where increases in pH and the removal of certain ionic species persisted. However, coring revealed varying degrees of cementation. After 3.8-year treatment, porosity reduction of up to 41.7% was obtained from mineralogical analysis on core samples collected at the upgradient gravel-Fe0 interface. Elsewhere, Fe0 filings were loose with some cementation. Fe0 corrosion and pore volume reduction at this site are more severe due to the presence of NO3- at a high level. Tracer tests indicate that hydraulic performance deteriorated: the flow distribution was heterogeneous and under the influence of interfacial cementation a large portion of water was diverted around the Fe0 and transported outside the PRB. Based on the equilibrium reductions of NO3- and SO4(2-) by Fe0 and mineral precipitation, geochemical modeling predicted a maximum of 49% porosity loss for 5 years of operation. Additionally, modeling showed a spatial distribution of mineral precipitate volumes, with the maximum advancing from the interface toward downgradient with time. This study suggests that water quality monitoring, coupled with hydraulic monitoring and geochemical modeling, can provide a low-cost method for assessing PRB performance.  相似文献   
19.
Geochemical and mineralogical changes were evaluated at a field Fe0-PRB at the Oak Ridge Y-12 site concerning operation performance during the treatment of U in high NO3- groundwater. In the 5-yr study period, the Fe0 remained reactive as shown in pore water monitoring data, where increases in pH and the removal of certain ionic species persisted. However, coring revealed varying degrees of cementation. After 3.8-yr treatment, porosity reduction of up to 41.7% was obtained from mineralogical analysis on core samples collected at the upgradient gravel-Fe0 interface. Elsewhere, Fe0 filings were loose with some cementation. Fe0 corrosion and pore volume reduction at this site are more severe due to the presence of NO3- at a high level. Tracer tests indicate that hydraulic performance deteriorated: the flow distribution was heterogeneous and under the influence of interfacial cementation a large portion of water was diverted around the Fe0 and transported outside the PRB. Based on the equilibrium reductions of NO3- and SO4(2-) by Fe0 and mineral precipitation, geochemical modeling predicted a maximum of 49% porosity loss for 5 yr of operation. Additionally, modeling showed a spatial distribution of mineral precipitate volumes, with the maximum advancing from the interface toward downgradient with time. This study suggests that water quality monitoring, coupled with hydraulic monitoring and geochemical modeling, can provide a low-cost method for assessing PRB performance.  相似文献   
20.
Polyethylene terephthalate bottles containing natural spring water were used to study the leaching effect of carbonyl compounds after one year storage under real conditions of exposure. Ultraviolet-B and ultraviolet-A spectra of direct sunlight were acquired during the experiment. Leaching of acetone, acetaldehyde, and formaldehyde reached steady state after 210 days of outdoor storage, with the following concentrations: 434 ± 22, 345 ± 18, and 94 ± 5 µg/L, respectively. The increase due to sunlight exposure in comparison with laboratory storage in the dark was around 10%, 16%, and 36%. The leaching process of all three carbonyl compounds was found to follow the first-order kinetics. Photo-degradation of Polyethylene terephthalate bottles and the appearance of carboxyl end-groups were followed by attenuated total reflectance infrared spectra. After 313 days of storage under direct sunlight, new peaks appeared in the regions of 1770–1920 cm?1 and 1685–1490 cm?1. Cations, anions, total dissolved solids, pH, and conductivity were also measured during the storage period. Additionally, microbiological measurements as well as statistical analyses were also carefully discussed.  相似文献   
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